Bioscience Technology articles from December 2004

Bioscience Technology archives from December 2004

Antibody-Based microarray.
December 1, 2004... Panorama Ab Microarray Cell Signaling Kit is the first product in a new line from Sigma-Aldrich. Antibody microarrays are valuable when researching diseases in which growth, invasion and transmission may result from an abnormal network of cell...

Multi-detection plate reader.
December 1, 2004... SpectraMax M5 five-mode multi-detection microplate reader system has primary applications for fluorescence intensity, absorbance, luminescence, Time-Resolved Fluorescence (TRF) and Fluorescence Polarization (FP) assays. A triple-mode cuvette...

Microfluidic, automated electrophoresis.
December 1, 2004... Experion automated electrophoresis system (Bio-Rad Laboratories) uses LabChip microfluidic technology (Caliper Life Sciences) to speed 1-D protein and RNA separation and analysis. After basic sample preparation similar to traditional gel...

Single quadrupole mass spec for HPLC. (Bioanalytical Instrumentation Focus.
December 1, 2004... Finnigan Surveyor MSQ Plus single quadrupole LC/MS detector extends HPLC detection sensitivity and is designed for routine HPLC applications. Thermo Electron Corp., 800-532-4752, www.thermo.com Use Info LINK 4M1104 or Call 800-287-0633 ...

ADME calculation prediction software.(Bioinformatics Focus)
December 1, 2004... VolSurf predicts ADME (absorption), distribution, metabolism and excretion) properties of drug candidates. Inappropriate compounds are eliminated before substantial time and money are invested in drug candidate testing. Tripos, Inc.,...

Protein expression automation.(Proteomics Instruments & Reagents Focus)
December 1, 2004... Information management system OrchestratorIMS is fully compatible with cloning techniques such as Gateway, TOPO and traditional methods. A rules-based understanding of molecular biology allows identification of planned cloning strategies that...

PCR in 96-well format.(Editor's Choice)
December 1, 2004... The 7900HT Fast Real-Time PCR system provides results in approximately 35 minutes in a traditional 96-well format. Shortened thermal cycling times increase productivity for researchers utilizing serial workflows. The complete system includes a...

Parallel synthesis system.(Editor's Choice)
December 1, 2004... Designed for the chemist conducting parallel synthesis, the Omni-Reacto Station has a temperature range of -30 to 220 C. Modular design and integrated block heater/cooler ensure temperature uniformity and eliminate the mess of melting ice....

Charged Aerosol HPLC Detector.(Editor's Choice)
December 1, 2004... Corona Charged Aerosol Detector (CAD) offers a robust HPLC detection technology. HPLC column eluent is nebulized and the resulting droplets dry at ambient temperature producing analyte particles. A second stream of gas is positively charged as...

2-D electrophoresis system.(Editor's Choice)
December 1, 2004... a2DEoptimizer automates gel casting to user-defined gradients to improve reproducibility and enhance resolution of protein separations. Once a gradient has been designed and stored, gels are cast automatically, providing consisten results. The...

Bcrp Targeted Mutation Mouse.(Editor's Choice)
December 1, 2004... Recent studies indicate that the Bcrp Targeted Mutation Mouse from Taconic is a useful model for studies of in vivo drug disposition and the role of ATP-dependent transporters in inflammation. The Bcrp model carries a disruption in the...

Human sequence microarray.(Editor's Choice)
December 1, 2004... NimbleGen's ENCODE microarray contains more than 384,000 unique 50met probes selected from 30 megabases of human sequence data specified by the ENCODE Project Consortium. These probes are tiled, or spaced apart, every 38 bases. This creates a...

Isocratic separation of proteins using a thermal gradient.(Tools & Techniques)
December 1, 2004... Introduction HPLC analysis at elevated temperatures reduces analysis time and improves resolution. Reduced viscosity at elevated temperatures results in significantly lower backpressure, allowing for high flow rates and short analysis...

Multifunction microplate reader.(Bioanalytical Instruments Focus)
December 1, 2004... Multifunctional microplate reader PHERAstar provides sensitivity and quick read-times in plate formats up to 1536-wells, and non-radioactive detection modes including: fluorescence intensity (including FRET), time-resolved fluorescence...

Microwave synthesis using low-temperature chemistries.(Bioanalytical Instruments Focus)
December 1, 2004... Discover CoolMate microwave synthesis system performs sub-ambient temperature chemistries for temperature-sensitive reactions including carbohydrate chemistry and the formation of carbanions and other highly reactive intermediates. The system...

Gel documentation and image analysis.(Bioanalytical Instruments Focus)
December 1, 2004... [InGenius.sup.12] gel documentation system accurately analyzes close-banded gels with its fully integrated camera, universal darkroom, and imaging software. GeneFlash gel documentation system rests inside its own compact darkroom, downloading...

NMR 900-MHz superconducting magnet.(Bioanalytical Instruments Focus)
December 1, 2004... The 900 [US.sup.2] actively-shielded-900 MHz superconducting magnet for NMR applications combines proprietary UltraShield and UltraStabilized technologies to deliver a high fieldstrength, activelyshielded magnet. This technology reduces stray...

Process LC systems.(Bioanalytical Instruments Focus)
December 1, 2004... Two new bench-top Pilot Bioprocess LC systems (500 ml/min and 1 liter/min) for liquid chromatography feature sanitary flow paths. The cGMP systems are intended for biopurifications using Adaptive PAT blending (TechniKrom) for precise buffer...

Refractive index detector.(Bioanalytical Instruments Focus)
December 1, 2004... Optilab rEX refractive index detector combines semiconductor photodiode technology and proprietary computer algorithms. Users can view the full range of instrument detection at all times. The dn/dc of a solvent can be measured at the same...

Centrifugal evaporator.(Bioanalytical Instruments Focus)
December 1, 2004... EZ-2 HCl benchtop centrifugal evaporator provides an efficient and safe means of routinely removing strongly acidic chemicals from samples. Inert and corrosion-proof materials enable high concentrations of hydrochloric acid and other acid...

Single quadrupole mass spec.(Bioanalytical Instruments Focus)
December 1, 2004... Finnigan Surveyor MSQ Plus single quadrupole LC/MS detector extends HPLC detection sensitivity and is designed to run routine HPLC applications effectively. Unknown chromatographic peaks can appear during the development of drugs, chemicals,...

Flash chromatography system.(Bioanalytical Instruments Focus)
December 1, 2004... IntelliFlash 280 fully automated flash chromatography system is compact enough to fit within tight flume hoods, and minimize set-up time and maximizes purification results by integrating a pump, column, detector, collector and controls. The...

Imaging system.(Bioanalytical Instruments Focus)
December 1, 2004... FluorChem SP imaging system features a 4-megapixel resolution camera combined with software that enables quick acquisition of publication-quality chemiluminescent images. The instrument offers a low noise characteristic CCD and is also useful...

Proteomics analysis.(Bioanalytical Instruments Focus)
December 1, 2004... Proteineer-LC is an LC-ESI-MALDI systemfor LC-based expression proteomics workflows. Its manufacturer, Bruker Daltonics, also offers Top-Down Proteineer capability on the apex-Qe Q-q-FTMS mass spectrometry system. The products allow...

Scientist-moderated online forum.(Bioinformatics Focus)
December 1, 2004... The Scientist Solutions Board is an international, multi-disciplinary and scientist-moderated Internet forum. Scientists can globally exchange ideas, problem solve and develop collaborative relationships via the discussion board and centralized...

Lead opimization software provides analysis of large data sets.(Bioinformatics Focus)
December 1, 2004... LeadNavigator, a chemically intelligent analytics product, allows analysis of large sets of chemical and numerical data through a single, intuitive interface. The product is a component of LION Lead Engine, LION bioscience's cheminformatics...

Trace-viewing software for sequence analyses.(Bioinformatics Focus)
December 1, 2004... Geospiza has updated Geospiza FinchTV, a free, cross-platform trace viewing software utility for use in DNA sequencing analysis. The newly-enhanced version of the freely-downloadable FinchTV soft-ware now incorporates sequence editing, insert...

ADME calculation, prediction software.(Bioinformatics Focus)
December 1, 2004... VolSurf (Tripos, Inc.) predicts ADME (absorption, distribution, metabolism and excretion) properties of drug candidates. Driven by the failure rate of drug candidates in late stage development, VolSurf eliminates inappropriate compounds before...

Chromatography data management.(Bioinformatics Focus)
December 1, 2004... EZChrom Elite version 3.1.6 (from Scientific Software, Inc.) is a chromatography data system that has been enhanced for support for Windows 2003 Server and for Windows XP Native Mode Active Directories. This release incorporates enhancements to...

Biological pathway visualization and analysis software.(Bioinformatics Focus)
December 1, 2004... PathwayAssist 3.0 desktop software for visualization and analysis of biological pathways includes a database of 500,000+ molecular interactions for pathway data mining, significantly improved visualization tools, and wizards for data import and...

Visual computing system.(Bioinformatics Focus)
December 1, 2004... Silicon Graphics Prism Linux OS-based computers combine standards-based Intel Itanium 2 processors, the Linux operating environment, and advanced graphics technology to addressing demanding visual computing problems. Real-world applications...

Basic instrument/LIMS interface.(Bioinformatics Focus)
December 1, 2004... LimsLinkExpress (Labtronics, Inc.) provides basic instrument to LIMS interfacing for laboratories that don't require the extensive security features and sophisticated processing capabilities that are included in Labtronics' full LimsLink...

Chromatography data system.(Bioinformatics Focus)
December 1, 2004... PerkinElmer Inc. has introduced version 6.3 of the TotalChrom Chromatography Data System. Package features include IRIS 3-D spectral processing software, a package offering a fully 21 CFR Part 11 compliant architecture, automated processing and...

Super computer links multiple processors.(Bioinformatics Focus)
December 1, 2004... POWER5-based server system from IBM can be easily clustered for high performance supercomputing. The new p5-575, a thin, blade server-like system, uses multi-chip packaging technology innovations to provide high-speed connections between eight...

LIMS software integrates genomics, proteomics labs.(Bioinformatics Focus)
December 1, 2004... LS * LIMS Software from Applied Biosystems increases productivity by integrating Applied Biosystems and third-party instrument interfaces, including the Applied Biosystems 3730 and 3730x1 DNA Analyzers, the ABI PRISM 7900HT Sequence Detection...

Lead optimization program.(Bioinformatics Focus)
December 1, 2004... WABE 1.3 lead optimization program generates analogs with the same shape but more desirable electrostatics. WABE is useful for exploring the chemical space around a lead compound to elucidate candidates with improved drug profiles or novel...

Genome exploration software.(Bioinformatics Focus)
December 1, 2004... DeCypher software and reconfigurable hardware components improve SPU performance for BLAST, HMM, Smith-Waterman and gene modeling analyses, yet are easy to maintain and install. Each application is available as an individual, turnkey solution...

Bioinformatics web portal.(Bioinformatics Focus)
December 1, 2004... Bioinformatics Central is a Web portal that consolidates and provides access to Invitrogen's comprehensive collection of bioinformatics tools, including Vector desktop software, as well as free online tools for cloning, RNAi and primer design,...

Pre-coat reagents for CE.(Proteomics Instruments and Reagents Focus)
December 1, 2004... CE has struggled with limitations caused by lack of control over electroosmotic force and flow (EOF), a natural occurrence in CE separations. UltraTrol products address separation hurdles to overcome these limitations in biochemical separation...

Proteomics software provides 2D gel analysis.(Proteomics Instruments and Reagents Focus)
December 1, 2004... Dymension software accurately analyzes 2D gels in seconds. A spot finding algorithm results in minimal post editing being needed and couples with an automatic gel alignment process to speed the whole imaging process fight through to results and...

HPLC column for peptide mapping.(Proteomics Instruments and Reagents Focus)
December 1, 2004... Jupiter Proteo 90A-pore HPLC column is offered for the analysis of peptide maps. Peptide fragments produced in a tryptic digest of a protein often exhibit significantly complex patterns, differing markedly from protein to protein. The resulting...

Protein expression automation.(Proteomics Instruments and Reagents Focus)
December 1, 2004... Information management system OrchestratorIMS (pictured, from NextGen Sciences) is compatible with cloning techniques such as Gateway, TOPO and traditional methods, The software enables planning experiments at a PC, and then carrying out the...

Protein workstation.(Proteomics Instruments and Reagents Focus)
December 1, 2004... The Protein Portfolio Platform is a combination of proven automation, on-board intelligent imaging and information tracking tools. The workstations are optimized for a growing series of protein applications including phage display, library...

Automated protein purification system for small-scale research.(Proteomics Instruments and Reagents Focus)
December 1, 2004... AKTAxpress TWIN is a fully integrated protein purification system that delivers totally automated, multi-step purification of His- and GST-tagged proteins for small scale research. A smaller version of GE Healthcare's AKTAxpress high-throughput...

Fluorescent dyes.(Proteomics Instruments and Reagents Focus)
December 1, 2004... MFP fluorescent dyes are ready for coupling to proteins and nucleic acids, and span the wavelength spectrum from green to far red. They offer photostability, a strong absorption, high fluorescence quantum yield and good water solubility....

Recombinant mouse proteins.(Proteomics Instruments and Reagents Focus)
December 1, 2004... Recombinant mouse proteins MBL-1 and MBL-2 are available from R&D Systems. Mannan binding lectin (MBL) belongs to the collectin family of innate immune defense proteins that bind an array of carbohydrate patterns on pathogen surfaces. Collectin...

Agrobacterium transformation kit.(New Products)
December 1, 2004... Enabling researchers studying plant genomics and proteomics to transform DNA into Agrobacterium with a minimum of hands-on time, the Agrobacterium Transformation Kit contains a single transformation solution with which A.rhizogenes or...

Small microassay plates.(New Products)
December 1, 2004... Originally designed for tissue-typing applications, this HLA/Terasaki small microassay plates is commonly used for microbatch protein crystallography. Conical wells avoid the spread of droplets away from the center for optimized crystallization...

Panel-mount coupling bodies.(New Products)
December 1, 2004... Panel-Mount APC Coupling Bodies provide added flexibility and mounting options to create secure connections for applications that include water filtration; distillation equipment; commercial dispensing equipment for water, ice cream, and juice;...

Silicone-jacketed hose.(New Products)
December 1, 2004... Hose features a cover of pure silicone that encases stainless steel over-braided PTFE hose to protect against high temperatures during handling by resisting heat transfer from the stainless steel. AdvantaPure, 888-755-4370, www.advanta-pure.com...

Genomic DNA purification.(New Products)
December 1, 2004... NucleoSpin 96 and NucleoSpin 8 Tissue Kits process samples without phenolchloroform extractions. These kits handle multiples of eight samples, and facilitate 96-column plates. The columns contain silica membranes with high DNA-binding capacity....

Fiber optic illuminator.(New Products)
December 1, 2004... Alpha 1501 fiber optic illuminator produces 150 watts of cold illumination while heat-blocking guards keep the unit cool to the touch. Options include a dual gooseneck with focusable tips and a ring light. LW Scientific, 800-726-7345,...

RT-PCR mixes.(New Products)
December 1, 2004... RT-PCR Master Mix (2X) and FideliTaq RT-PCR Master Mix (2X) allow one-step RT-PCR reactions in a single tube. The ready-to-use mixes are available with Taq DNA Polymerase, optimized for routine detection, or FideliTaq DNA Polymerase, optimized...

Laboratory Hoods.(New Products)
December 1, 2004... Protector Premier Laboratory Hoods provide a molded, one piece, chemical-resistant fiberglass interior, and an exterior constructed of glacier white epoxy-coated steel that complements laboratory furniture. Clean-Sweep airflow slots allow clean...

Instrument interfacing online resource.(New Products)
December 1, 2004... The online Resource Library includes dozens of articles, white papers, and case studies that provide information and insight into all aspects of instrument interfacing. Popular white paper topics include "Planning a Successful Instrument...

Miniature translation stages.(New Products)
December 1, 2004... MFA series motorized miniature translation stages deliver 25-mm travel range, 100 nm minimum incremental motion, and repeatability of 300 nm (unidirectional), in a 20 mm X 45 mm X 140 mm package. The stages meet find applications including...

Confocal microscope Fr live cell imaging.(New Products)
December 1, 2004... Olympus FluoView FV1000 confocal microscope is offered for imaging live organisms with minimal specimen damage. The unit's SIM Scanner incorporates two independent, fully synchronized laser scanners for simultaneous laser stimulation and...

Temperature Transmitter.(New Products)
December 1, 2004... SERIES DX DeviceNet Temperature Transmitter, a compact, four-channel DIN mounted unit, brings smart sensing technology capabilities to sensor networks. It simplifies the installation process; reduces total installation costs; and collects,...

Precision balance.(New Products)
December 1, 2004... XP precision balance controls calibration, testing, and optimization. Color touch-screen technology combines clarity with a secure, informative terminal. Fast weighing cycle increases lab productivity concurrently with automation efficiency to...

Membrane test unit.(New Products)
December 1, 2004... DSS Pilot Unit Combi M39/M3.8 combines flat sheet and spiral wound designs. It consists of a DSS LabStak M39 and a housing for 3.8" spiral elements. The module has a flat sheet membrane area of 1 [m.sup.2] and a 3.8" spiral element with a...

Culture dishes.(New Products)
December 1, 2004... Culture dishes feature ultra-thin, gas permeable Lumox fluorocarbon film base to provide cell viability and homogeneous cell growth, even with problematic cells. Oxygen and C[O.sub.2] are exchanged across the surface of the film, simulating...

Digital CCD Camera.(New Products)
December 1, 2004... Digital CCD Camera offers quantum efficiency with 1390 X 1024 pixel resolution. Digital temperature compensation maintains noise performance at a constant level regardless of ambient temperature fluctuations. All functions are remotely...

50-mW diode lasers.(New Products)
December 1, 2004... The Radius 405 diode laser is a 50mW self-contained diode laser operating at 405 nm. The continuous-wave laser features a cylindrical housing with drive electronics and a cooling fan integrated within the laser head. This configuration, which...

Automatic biohazard waste can.(New Products)
December 1, 2004... The lid on the Scienceware Touch Free Automatic Waste Can closes automatically after disposal to keep users safe and contents secure. Bright orange color and a prominent biohazard warning label announce the contents and aid in separating and...

HPLC carts.(New Products)
December 1, 2004... High Performance Liquid Chromatography (HPLC) Carts efficiently stack up to 800 lbs of HPLC equipment while freeing benchtop space. Carts are offered in two sizes: one is based on a 24" X 30" platform (single experiment), while the other on a...

Automated software control.(New Products)
December 1, 2004... Polartherm total temperature control software operates remotely while maintaining communication with existing HPLC equipment. The unit takes advantage of temperature gradients during chromatographic runs, as it is capable of hot and cold...

Vibration control system.(New Products)
December 1, 2004... Portable 8000 Series vibration control system uses active feedback to achieve high levels of vibration isolation for high-resolution instruments such as and photo-imaging microscopes. It isolates all six possible translational and rotational...

Stainless filter housings.(New Products)
December 1, 2004... Millistak+[R] and Millistak+ HC 316L stainless steel filter housings streamline multiple stages of mammalian cell culture clarification into one efficient, cost-saving step. A compression mechanism produces consistent sealing pressure and fast...

Remote-controlled safety cabinets.(New Products)
December 1, 2004... Available in various widths, Heraeus[R] HERAsafe[R] KS Class II safety cabinets improve comfort and maximize contamination prevention. KS models set parameters remotely via handheld controller, which is used in conjunction with an eye-level...

Microwave fixation systems.(New Products)
December 1, 2004... Microwave Fixation System preserves levels of enzyme-regulated neurotransmitters and metabolic substances in the brain at concentrations that exist in the living tissue, while brain size and structure remain unchanged. Uniform fixation of the...

Personal screening synthesizer.(New Products)
December 1, 2004... Advantage Series 2410 personal screening synthesizer helps chemists who work with small amounts of material replicate the thermal and mixing conditions seen in larger production reactors. It provides efficient process development for new...

Peristaltic pumps.(New Products)
December 1, 2004... With NEMA 4X washdown sealed enclosures, 520 peristaltic pumps offer superior reliability and performance under harsh processing conditions. For metering, dosing, and transferring of corrosive or sensitive fluids, this series is suitable for...

Motor-driven XY stage.(New Products)
December 1, 2004... M-684 PIline XY-translation stage is a piezo-motor-driven system for microscopy applications where smooth and backlash-free, high-resolution motion and convenient control via joystick are required. These applications include biotechnology,...

Memmert incubators.(New Products)
December 1, 2004... Memmert BE and BP series incubators achieve precise temperature control from 5 C above ambient up to 70 C. Conditions for homogeneous Incubation temperatures are achieved by utilizing double doors and all-around heating. In sizes from 1.1 to...

Confocal microscope systems.(New Products)
December 1, 2004... Digital Eclipse C1-Plus Modular Confocal System features scan head optics that boost optical performance to 400 nm. The C1-Plus also includes faster image acquisition with bi-directional scanning, support for X and Y scan axes rotation and new...

Multi-barbed fittings of various materials.(New Products)
December 1, 2004... Thermobarb multi-barbed fittings find use in a variety of applications. They work well with tubing and hose made from soft materials such as PVC, silicone, polyurethane, TPR, and additional materials. These fittings are precision molded in...

Bioassay tray supports culture, screening.(New Products)
December 1, 2004... QTray bioassay tray supports large-scale culture and screening of bacterial and yeast libraries, and has been redeveloped for rapid workload management. Formation of condensation, following either media pouring or a change in temperature from...

Filtered Balance System.(New Products)
December 1, 2004... XPert Filtered Balance Systems protect users during weighing procedures by keeping powders and particulates contained and away from the operator. Interior depth of 23" accommodates large micro and analytical balances. Containment-enhancing...

Automated purification of viral nucleic acids.(New Products)
December 1, 2004... MagAttract Virus Mini M48 Kit provides a fully automated procedure for simultaneous purification of viral DNA and RNA from 400 [micro]1 serum and plasma for sensitive detection in downstream assays. Yields are linear, allowing quantitative...

DNA/RNA-free pipette tips and filtered pipette tips.(New Products)
December 1, 2004... BIO-CERT pipette tips and filtered pipette tips are offered for applications such PCR, DNA/RNA purification, sequencing, bioluminescence, ATP-detection, and others. The products are lot-tested for sterility and are free of DNA, RNase,...

Liquid handling products.(New Literature)
December 1, 2004... New edition of Biohit liquid handling catalog cover a selection of the company's products, as well as providing information on how to to look after pipettors and to consistently achieve the best pipetting results. Calibration service, technical...

FRET Probes.(New Literature)
December 1, 2004... FRET Probes brochure features a general overview of Fluorescence Resonance Energy Transfer (FRET) analysis. Eighty-plus products are covered, including classic FRET dyes, DABCYL Plu dyes, QX quenchers, FRET building blocks, and FRET protease...

Laboratory glassware.(New Literature)
December 1, 2004... Kimble and Kontes catalogs feature two laboratory glassware brands from the one source. Products for both chemistry and the life sciences, including a full range of both reusable and disposable products are featured in the 160 page Kimble...

Vibration control products.(New Literature)
December 1, 2004... Kinetic Systems announces the availability of their new 52-page User Guide detailing their complete line of high-performance vibration control equipment. The catalog introduces two new series of Active Electronic Vibration Isolation Systems and...