Bioscience Technology articles from August 2005

Bioscience Technology archives from August 2005

Online Conference covers strategies for assay development and screening.(EDITOR'S Note)
August 1, 2005... BioDiscovery Online Conference and Expo will be Webcast live on October 26th. Following the lead of this February's inaugural conference, the fall meeting will feature a group of distinguished researchers presenting talks on a number of topics...

Confocal laser fluorescence microscope.(EDITOR'S Choice: AUGUST'S TECHNOLOGY)
August 1, 2005... Digital ECLIPSE Clsi confocal laser fluorescence microscope system simultaneously acquires fluorescence spectra over a 320 nm wavelength range at 10 nm spectral resolution, or over smaller ranges at 5 nm or 2.5 nm spectral resolution. The...

Modified sequencing grade Pepsin.(EDITOR'S Choice: AUGUST'S TECHNOLOGY)
August 1, 2005... Highly purified Pepsin is modified to reduce autolysis, improve stability and simplify protein sequencing procedures. The modified Pepsin endoproteinase offers consistency of activity from lot to lot, specificity free from other...

Clone storage plates.(EDITOR'S Choice: AUGUST'S TECHNOLOGY)
August 1, 2005... EasyClone 384 plates (Whatman BioScience Group) are single, versatile devices that provide a simple way of storing clone samples. Clone samples can be stored in half-height plates at room temperature using the same technology that has preserved...

Quantum dot labels.(EDITOR'S Choice: AUGUST'S TECHNOLOGY)
August 1, 2005... T2 EviTag second generation luminescent label from Evident Technologies has a proprietary natural coating that increases flexibility, broadens applications and may possibly reduce testing costs in biological assays and other types of life...

High-content screening system.(EDITOR'S Choice: AUGUST'S TECHNOLOGY)
August 1, 2005... ImageXpress Micro, a modular, high-resolution CCD imager with upgradeable options such as laser auto-focus for rapid plate-scanning and transmitted light for bright field utility is offered with three new software packages. MetaXpress provides...

Hybrid mass spectrometer.(EDITOR'S Choice: AUGUST'S TECHNOLOGY)
August 1, 2005... LTQ Orbitrap a hybrid mass spectrometer is offered for small molecule research, drug discovery, proteomics, metabolite identification, and metabolomics. Combining Orbitrap electrostatic ion trap technology with a Finnigan LTQ front-end, the...

Analyze whole blood for white blood cells.(EDITOR'S Choice: AUGUST'S TECHNOLOGY)
August 1, 2005... New side scatter feature offered with the Guava EasyCyte system allows analysis of whole blood for different types of white blood cells, without having to stain or fix the cells. The granular structures in the cytoplasm of granulocytes, a type...

Molecular Imaging Software.(EDITOR'S Choice: AUGUST'S TECHNOLOGY)
August 1, 2005... Kodak Molecular Imaging Software V. 4.0, for the acquisition, quantitative analysis, manipulation, and databasing of scientific images, offers enhanced Region of Interest definition and analysis tools that include a Magic Wand, Peak Finder...

RNA research: reinvigorated by major breakthroughs.(Cover Story)
August 1, 2005... With the emergence of RNA interference (RNAi) as a powerful analytical tool in mammalian genetic screening, the discovery of strong correlations between the 217 known microRNAs (miRNAs) in the development and differentiation of tumors, and the...

Microplate stacker.(ARRAYS)
August 1, 2005... Self-contained automated plate handling capability is available for the Aj100 microarray spotter. Stacker module Aj020 handles up to 48 microplates without user intervention, and automates lid lifting to address sample evaporation during...

Personalized DNA microarrays.(ARRAYS)
August 1, 2005... The GEArray personalized microarray program (SuperArray Bioscience Corp.) allows individual tailoring of content on low-density microarrays with any set of human, mouse or rat genes. Customized microarrays utilize the same technology platform...

Microbial whole genome resequencing technology.(ARRAYS)
August 1, 2005... NimbleGen Systems offers a new technology for rapid microbial resequencing. The ability to identify the genetic variation between a reference genome and closely related microbial isolates is important for studying antibiotic resistance, the...

DualChip DNA Microarray.(ARRAYS)
August 1, 2005... DualChip Microarray Systems are offered for rapid gene expression analysis and pathway identification in toxicology, neuroscience, signal transduction, and research on aging using human or rat models. Xmer technology-based probes contain...

Microarray Processing System.(ARRAYS)
August 1, 2005... Little Dipper Microarray Processing System (SciGene) completely automates the steps used for processing DNA microarrays after hybridization. The system consists of a programmable rotary robotic arm that moves racks of arrays through five...

Whole rat genome array.(ARRAYS)
August 1, 2005... Whole-genome oligonucleotide microarray for the study of the rat contains probes for more than 41,000 genes and transcripts. The array provides the genome coverage, validated genomic content and sensitivity needed to assess the effect of...

Genomic DNA array labeling.(ARRAYS)
August 1, 2005... ULS (Universal Linkage System) arrayCGH Labeling Kits offer direct, non-enzymatic labeling of genomic DNA for microarray-based comparative genomic hybridization analysis. Including the ULS labeling molecule bound to a choice of fluorescent dye...

High throughput microarray polymer platforms.(ARRAYS)
August 1, 2005... Polymer platforms are offered for utilization with biochips, high throughput microarray (HTA) products include a standard format slide (Slide 1), a 12-well slide to simultaneously process 12 samples (Slide12), and a specialized 96-well HTA...

Electronic laboratory notebook.(BIOINFORMATICS)
August 1, 2005... E-Workbook is a comprehensive, extensible electror notebook (ELN) for scientists in any discipline. The underpinning the notebook allows drug discovery scientists, including chemists, biologists and pharmacologists, to record, share and report...

Software measures DNA damage.(BIOINFORMATICS)
August 1, 2005... Comet Assay IV interactive video-based software system measures DNA damage using single cell gel etectrophoresis (SCGE) Using a high-definition video camera attached to a microscope, the system provides real-time cell scoring by transferring a...

Chromatography data system.(BIOINFORMATICS)
August 1, 2005... Version 8.0 of the Atlas chromatography data system (CDS) provides enhancements in data acquisition and integration with LIMS. Improvements to the instrument control architecture enhance network resilience, and secure, robust communication has...

Metabolomics and biomarker profiling software.(BIOINFORMATICS)
August 1, 2005... Applied Biosystems, with MDS Sciex, has introduced MarkerView Software, a package for metabolomics and biomarker profiling analysis. The software allows researchers performing non-targeted metabolomics and protein biomarker profiling studies to...

Lab informatics software.(BIOINFORMATICS)
August 1, 2005... Benchware lab informatics product suite includes a range of packages. 3D Explorer provides chemical visualization and decision support capabilities. HTS DataMiner offers functionality dedicated to the location, definition and prioritization of...

Mounting medium.(VectaMount AQ aqueous)(Brief Article)
August 1, 2005... VectaMount AQ aqueous, hard-setting mounting medium is offered for use with AEC and other enzymatic substrates when products are soluble in alcohol or other organic solvents. The product is also compatible with other peroxidase and alkaline...

Human IL-4 Screening Set for ELISA development.
August 1, 2005... Human IL-4 Screening Set contains the basic components and protocol to develop 5 colorimetric sandwich ELISA plates for cytokine quantitation using 100 m l/well of cell culture supernate. Reagents include coating and detecting antibodies....

Phosphospecific antibodies.(IMMUNO KITS & REAGENTS)
August 1, 2005... BIODESIGN International has expanded its line of phosphospecific antibodies and antibodies to phosphorylated proteins. Phosphospecific antibodies are expensive, difficult to work with, and often require screening and testing of different...

T Cell Activation/Expansion Kit.(IMMUNO KITS & REAGENTS)
August 1, 2005... The T Cell Activation/Expansion Kit consists of Anti-Biotin MACSiBead particles and biotinylated antibodies against human CD2. CD3 and CD28. Particles loaded with biotinylated antibodies are used to mimic antigen-presenting cells and activate...

cAMP Phosphodiesterase Assay Kit.(Product Information)(Brief Article)
August 1, 2005... PDELight HTS cAMP Phosphodiesterase Assay Kit screens for phosphodiesterases in high throughput applications. The homogeneous assay uses bioluminescent detection. Phosphodiesterases are enzymes in the cell that act as gating mechanisms. Their...

Human p27 EIA Kit.(Product Information)(Brief Article)
August 1, 2005... Human Total [p27.sup.Kipl] Titer-Zyme EIA Kit quantitatively determines human p27 in cell lysates, p27Kipl is a member of a family of CDK inhibitors (CDIs) that bind to cyclin/ CDK complexes and arrest cell division. The biochemical has been...

Serum IgG Removal Kit.(Product Information)(Brief Article)
August 1, 2005... ProMax Serum IgG Removal Kit contains magnetically responsive ProMax IgG removal particles and serves as a binder/washer. The protocol removes IgG and enriches samples for less abundant serum proteins in 30 minutes or less. The system allows...

Renin Inhibitor Screening Assay.(IMMUNO KITS & REAGENTS)
August 1, 2005... Cayman Chemical Renin Inhibitor Screening Assay Kit is offered in a 96-well format for evaluating human renin inhibitors. The assay utilizes a renin-based synthetic peptide substrate which incorporates the fluorophore EDANS at one end and an...

Alzheimer's research tools.(IMMUNO KITS & REAGENTS)
August 1, 2005... The quest for the causative agent in Alzheimer's Disease has recently focused on the precursors of amyloid plaques. These precursors are part of an array of processed APP variants, Tau isoforms and secretase components that play a role in...

Ras GTPase ELISA.(Produt Infoamation)(Brief Article)
August 1, 2005... Ras GTPase Chemi ELISA detects and quantifies activated Ras. This ELISA-based kit is sensitive, and its high throughput format enables simultaneous screening of 1 to 96 samples in a single experiment. The kit is suited for the study of novel...

Mouse Interferon ELISA.(IMMUNO KITS & REAGENTS)
August 1, 2005... IFN and IFN-a are prototypical members of the type I interferon family. Produced by most cell types and upregulated with viral infection, they exhibit potent anti-viral activities. These Mouse Interferon (IFN) ELISA Kits can distinguish between...

Automated quantitative analysis of proteins: the assay is a microfluidic version of SDS-PAGE, where each step of the slab gel process--sample loading, electrophoresis, staining, destaining, and detection--is integrated into a microfluidic device.(APPLICATION NOTE)
August 1, 2005... As experimentation becomes more complex and broader in scope, it becomes infeasible to compare, analyze, and make decisions based on gel data alone. Microfluidic assays offer a quantitative alternative to SDS-PAGE. The LabChip 90 system...

Cell immortalization line.(ATCC)(Brief Article)
August 1, 2005... Products for cell immortalization enable researchers to use the same materials throughout a project without having to establish new cultures. Both immortalized cell lines and the tools for immortalizing cells are available. Telomerase reverse...

Nucleic acid sample detection.(Vidiera NsD Nucleic Sample Detection Platform )(Brief Article)
August 1, 2005... Vidiera NsD Nucleic Sample Detection Platform is offered for fully automated detection of nucleic acids, post amplification. The platform for molecular pathology labs separates DNA molecules by capillary electrophoresis (CE), with software...

On-line biomass monitoring.(Medical equipment)(Brief Article)
August 1, 2005... AberProbe can be used in most ports and top plates on conventional fermenters with mammalian, yeast, bacteria and fungal cells, yet it is optimized for use in microbial fermentations under highly aerated conditions. Combined with the Biomass...

Electronic pipettes.(Product information)(Brief Article)
August 1, 2005... BioPette E electronic pipettes feature a motorized piston drive and are simple to use. Single and multi-channel versions incorporate a high precision stepper motor and microprocessor to accurately monitor and control piston movement. A...

Multilabel microplate reader.(Chameleon multilabel microplate reader )(Brief Article)
August 1, 2005... Chameleon multilabel microplate reader is available with MikroWin instrument control and data analysis software. The optical design of this compact reader allows up to six measurement technologies: liquid scintillation counting, luminescence,...

Non-Invasive Blood Pressure monitoring for mice and rats.(NEW Technology)
August 1, 2005... Non-Invasive Blood Pressure (NIBP) Monitor tests 1, 2, 4 or 8 animals simultaneously with interchangeable platforms for mice and rats. With a built-in controller, a PDA or a PC, the unit is capable of measuring conditioned animals at about...

Digital histology platform.(MIRAX SCAN fully automated digital histology system )(Brief Article)
August 1, 2005... MIRAX SCAN fully automated digital histology system facilitates the process of assessing pathological specimens. An automated scanner produces a high-resolution, digitized data set (digital slide) of the specimen, providing diagnoses and...

Ultra-High Throughput Microwave Reaction System.(Product information)(Brief Article)
August 1, 2005... MARSXpress Ultra-High Throughput Microwave Reaction System processes up to 40 high-pressure vessels per run. The system offers adaptive, continuous temperature and pressure feedback control for all vessels without the need for temperature and...

Eicosanoid competitive ELISA.(Brief Article)
August 1, 2005... Prostaglandin E2 (PGE2), Leukotriene B4 (LTB4), Cyclic AMP and Cyclic GMP Competitive ELISA are based on the competition between eicosanoid in the standard or sample and alkaline phosphatase-coniugated eicosanoid, for a binding to a limited...

Purify microbial DNA.(NEW Technology)
August 1, 2005... WaterMaster DNA Purification Kit provides the liquid reagents needed to purify microbial DNA from any water source after passage through a filter. DNA can be purified from bacteria and eukaryotes, and can be used for restriction digests, PCR,...

Microscope series.(Accu-scope, Inc.'s product)(Brief Article)
August 1, 2005... The 3000 Series microscopes for digital imaging are available with either semi-plan or plan objectives, HWF10 x /18 mm eyepieces, and either a binocular or trinocular viewing head. Optional accessories are available for digital imaging, phase...

Fractionator System.(NEW Technology)
August 1, 2005... The flashPAGE Fractionator System is a revolutionary electrophoresis device for the rapid, streamlined purification of small nucleic acids, such as siRNAs and microRNAs. Small RNA and DNA molecules are purified in approximately 12 minutes. The...

DNA polymerase.(NEW Technology)
August 1, 2005... LA Taq Hot Start, for PCR amplification of long (up to 43 kb) DNA fragments, contains LA Taq, which possesses 3'-> 5' exonuclease activity and provides high fidelity (6.5x), plus a neutralizing monoclonal antibody to Taq. This antibody binds to...

Dual autosampler.(NEW Technology)
August 1, 2005... ExpressLC-800 rapid gradient system features expanded functionality that doubles its throughput. The software drivers and hardware accessories support CTC Analytics' Twin-PAL Autosampler, ensuring sample delivery at a pace that fully optimizes...

Reagent reservoirs.(NEW Technology)
August 1, 2005... Deep Well and Low Profile Reservoirs feature low-binding polypropylene construction and offer chemical and heat resistance for aggressive solvents. Pyramid Bottoms reduce reagent waste by providing a collection area for low dead volume....

Laboratory labeling system.(NEW Technology)
August 1, 2005... LABXPERT Labeling System enables users to label vials, vial tops, slides, well plates and other laboratory vessels. Built-in lab applications include vial templates, one-touch time and date stamp, auto serialization for fast alloquots, bar...

Enterolactone EIA kit, competitive assay.(NEW Technology)
August 1, 2005... Enterolactone, a mammalian lignan with an estrogen-like diphenolic structure, is produced by intestinal bacteria from two plant precursors (matairesinol and secoisolariciresinol) obtained in the diet. Enterolactone and other lignans and...

Protein gel electrophoresis.(NEW Technology)
August 1, 2005... Native NEXT GEL non-denaturing gel electrophoresis kit allows high resolution of proteins in their native conformation by an agarose-based gel format. Able to be run with both basic and acidic proteins, the kit is compatible with all supporting...