Bioscience Technology articles from April 2003

Bioscience Technology archives from April 2003

Compact, refrigerated centerifuge.
April 1, 2003... Model 5702 R centrifuge has a maximum speed of 3,000 Xg and offers a choice of fixed-angle or swing bucket rotors. Round bottom and conical tubes from 1.1 to 85 ml are accommodated, and 20 X 10 ml blood tubes or 30 X 15 ml conical tubes can be...

Imaging-based cellular assays.
April 1, 2003... FDSS imaging based plate reader for cell-based assays has a modular design that allows running either fluorescence based assays, such as intracellular calcium, membrane potential, and ion channel FRET, or flash luminescence based assays, such...

3D Stereo fluorescence microscopy.
April 1, 2003... Leica Fluo Combi, an accessory for the Leica MZ FLIII fluorescence microscope, outfits new or installed microscopes with both 3D stereo and high-resolution compound objectives. Easy, infocus and parcentric switching is provided from a 1 X Plan...

Microarray reagent systems.
April 1, 2003... Pronto![TM] cDNA and Universal Microarray Reagent Systems, for printing and hybridizing cDNA and long oligonucleotide arrays, offer a complete microarray solution from printing through hybridization. Reagents are optimized for use with Corning...

Electronic pipettes. (Pipettor Focus).
April 1, 2003... SofTouch Electronic Pipettes feature a feather-touch button and perform multiple liquid handling functions, including pipetting, reverse pipetting, multiple dispensing, sequenced dispensing, diluting, and mixing. Four single channel pipette...

SPR-MS proteomics research system. (Editor's Choice).
April 1, 2003... The Biacore[R] 3000 SPR-based (surface plasmon resonance) research system, for the study of biomolecular interactions, has been made more powerful through the incorporation of automated and increased capacity recovery functionality and direct...

Research bioreactor. (Editor's Choice).
April 1, 2003... The Biostat[R] i modular bioprocess system, an enhanced, entry-level research tool, is capable of running one or two experiments simultaneously. Low maintenace single-walled spinner flasks or stirre-tanks may be used, which increases the...

Soil DNA isolation.
April 1, 2003... The UltraClean-htp[TM] 96 Well Soil DNA Kit purifies cellular or microbial genomic DNA from 96 soil samples at one time. The kit efficiently lyses microbes, spores or fungi utilizing bead beating technology on a high-velocity shaker. Released...

Ductless hood.
April 1, 2003... Aura[TM] Ductless Fume Enclosures protect workers from hazardous fumes, odors and particulates. Units can be fitted with both HEPA and carbon filters, and custom units are available for enclosing virtually any size equipment. Maximum protection...

Mouse Housing. (Editor's Choice).
April 1, 2003... The Mouse House[TM] is an enrichment device used to create an environment that encourages a wide range of natural mouse behaviors such as jumping, climbing, squeezing through holes and sleeping during daylight hours. Abnormal stereotyped...

Portable incubator for production scale roller systems. (Editor's Choice).
April 1, 2003... The Breeder[TM] soft-sided, portable incubator, for use with large scale, multiple deck roller culture systems, is a less expensive alternative to standard hard-sided incubators. Space is utilized flexibly in the cell culture laboratory. With a...

Microdispenser. (New Products).
April 1, 2003... Redesigned Hydra[R] II Microdispenser offers a lightweight urethane plastic housing, pipetting speed control, interactive backlit liquid crystal display and new intuitive programming controls. It can be configured with 96 100, 290, 580 and...

DNA isolation. (New Products).
April 1, 2003... NucPrep[TM] isolates high-quality DNA from a wide variety of plant and animal tissues: This formulated chemistry purifies 96 samples of DNA from plant tissue, and both digests and purifies DNA from any animal tissue in 2.5 hours or less. It...

Cancer and apoptosis antibodies and antigens. (New Products).
April 1, 2003... Biodesign International offers a comprehensive line of monoclonal antibodies, polyclonal antibodies and purified antigens related to cancer and apoptosis. Products include: activating transcription factor-1 thru 3, Bax, cancer markers to...

Solvent reservoir. (New Products).
April 1, 2003... "Bottomless solvent reservoir" a 1L pump package, replaces a solvent reservoir, reducing problems associated with flash purification. With a built-in pump system, the reservoir replacement eliminates allows uninterrupted purification using...

Biological safety cabinets. (New Products).
April 1, 2003... ESCO Biological Cabinets provide pre-filter and HEPA filters that are 99.999% efficient for 0.3 micron and provide better than class 100 clean air. Spacious interior has a stainless steel work surface with an ergonomic sloping front edge....

MMP observation kit. (New Products).
April 1, 2003... MMP in situ Zymo-Film is offered for the observation of the enzyme activity of matrix metalloproteinases (MMPs) in tissue specimens, which are known as an indicator of carcinogenesis and other physiological conditions. It is composed of a layer...

ATP-Dependent DNase. (New Products).
April 1, 2003... Plasmid-Safe[TM] ATP-Dependent DNase selectively digests contaminating chromosomal DNA, which is not effectively removed from plasmid preps by columns or resins. The result is cleaner plasmid preps, a greatly reduced chance of cloning E. coli...

Freezers. (New Products).
April 1, 2003... VIP (Vacuum Insulation Panel) freezers increase capacity without increasing floor space requirements. Highly efficient insulating materials allow wall thickness to be reduced and capacity increased. Five freezer models are offered, including...

Carpal tunnel syndrome: a rising statistic among laboratory workers. (Tools & Techniques).
April 1, 2003... Introduction Ergonomic injuries are widely recognized as a major factor in work place health. About one-third of all occupational injuries and illnesses stem from over exertion and/or repetitive motion. The cost to industry in workers'...

Optimization of RNA amplification for array analysis: protocols amplify rare RNAs for array analysis. (Tools & Techniques).
April 1, 2003... Introduction Experiments involving glass microarrays typically require as much as 20 [micro]g of total RNA or 2 [micro]g of poly(A) RNA for cDNA labeling and subsequent hybridization. However, obtaining sufficient amounts of RNA for array...

Particle characterization. (New Products).
April 1, 2003... Multisizer[TM] 3 meets and exceeds new ISO Standards for particle sizing, providing complete audit trails for each step. The instrument is CFR Part 11 compliant. High-speed digitalization of the signal allows the use of pulse area analysis and...

Vertical Array Loader. (New Products).
April 1, 2003... Vertical Array Loader (VAL) expands the capabilities of the CRS Dimension4[TM] automation platform to provide fast, random access to microplates in vertical shelves, instruments with multiple nests, and stacked instruments. It consists of an...

1536-well NanoWell plates. (New Products).
April 1, 2003... NanoWell 1536-well assay plate, for high and ultra high throughput screening, features a round well design that prevents wicking and cross-contamination. Cyclo-olefin copolymer (COC) is solvent resistant and cell growth-compatible, with low...

Tissue Microarray Analysis Service. (New Products).
April 1, 2003... High-Throughput Tissue Microarray (TMA) Laboratory Service is capable of analyzing TMAs 700% faster than the current industry standard. Using proprietary TMA software, coupled with multiple digital microscopes, provides high-throughput slide...

Protein identification software. (New Products).
April 1, 2003... ProteinLynx[TM] Global SERVER 2.0 suite is now available on the IBM[R] eServer pSeries 630. The IBM eServer is equipped with IBM POWER4 microprocessors, the first "server on a chip," containing two one-gigahertz processors and self-healing...

Genetic predisposition kits. (New Products).
April 1, 2003... This family of genetic predisposition kits is for a range of diseases, which includes simple microplate assays for high volume testing for 1-3 mutations and novel multiplex strip test for 3-40 mutations. The assays can be performed in 5 hours...

Totally automated peptide synthesizer. (New Products).
April 1, 2003... Apogee totally automated peptide synthesizer allows new or experienced peptide chemists alike can prepare peptides up to 50 amino acids long as easily as short sequences. Simple-to-use software, featuring preprogrammed Fast Boc and Fast Fmoc...

Biological safety cabinet. (New Products).
April 1, 2003... SterilchemGARD[R] III Advance[degrees] ergonomically enhanced biological safety cabinet is offered for Class II, Type B2 installations where total-exhaust is required. The cabinet avoids air re-circulation and generates 100% exhaust to protect...

Automated molecular biological workstation. (New Products).
April 1, 2003... The Brooks-PRI Automation, Inc. Nanoliter Scale Reactor (NLSR) workstation incorporates the Nano-Pipettor (NP), which processes 96 reactions in parallel and suits numerous biological applications. Using only nanoliters of reagent per reaction,...

Dye terminator removal resin. (New Products).
April 1, 2003... MagDTW[TM] dye terminator removal technology is an improved DNA sequencing reaction clean-up method that generates high-quality data. Sequencing reaction products are adsorbed to magnetic particles, washed with alcohol, and eluted in water. The...

Modeling, simulation software. (New Products).
April 1, 2003... Accelrys, a wholly owned subsidiary of Pharmacopeia, Inc. has released Cerius2 4.8 modeling and simulation environment for SGI IRIX workstations and other servers. Scientific application modules in this release provide new chemical libraries...

Cautery System. (New Products).
April 1, 2003... Gemini Cautery System 1 can cauterize at both low and high temperature. System requires 1 (1300 F/704 C) or 2 batteries (2200 F/1204 C) to operate. When using low temperature a spacer is provided to hold the place of the second battery. The...

Online bibliographic record resource. (New Products).
April 1, 2003... An enhanced version of EMBASE.com (www.embase.com), version 3.0, is now available. It allows users to search more than 15 million EMBASE and MEDLINE bibliographic records simultaneously using an intuitive search interface. Linking enables users...

a non-radioactive, colorimetric ELISA for MAP kinase activity: unbound biotinylated substrate allows determination of endogenous MAPK activity levels. (Tools & Techniques).
April 1, 2003... Introduction The mitogen-activated protein kinase (MAPK) cascade is an evolutionarily conserved signaling pathway that controls fundamental cellular processes such as proliferation, differentiation, survival and apoptosis in all...

384-Well DNA Binding filter plates. (New Products).
April 1, 2003... Easy to automate method for PCR purification using the Whatman 384-Well DNA Binding microplate. The plate contains a membrane engineered for the high throughput preparation of doublestranded DNA. The protocol for PCR cleanup incorporates a high...

Antibodies to stem cell markers. (New Products).
April 1, 2003... CHEMICON International, Incorporated has announced the availability of new reagents for the identification of pluripotent stem cell markers. These include monoclonal antibodies to Stage-Specific Embryonic Antigen 1, Stage-Specific Embryonic...

C18 for SPE. (New Products).
April 1, 2003... Prevail[TM] C18 is waterwettable and does not require organic solvent preconditioning; it accepts aqueous samples directly. Eliminating the organic preconditioning step reduces the use of solvents. The C18 for SPE is a silica-based C18 sorbent,...

Ultra high throughput genotyping system. (New Products).
April 1, 2003... SNPlex a reagent and software product facilitates ultra high throughput genotyping using the Applied Biosystems 3730xl and 3730 DNA Analyzers. The system uses multiplexing (multiple reactions in a single tube or well) to rapidly identify large...

Uniform magnetic microspheres. (New Products).
April 1, 2003... COMPEL[TM] uniform superparamagnetic microspheres are available in diameters of 3, 6, and 8 mm. For applications that demand uniform bead response, such as miniaturized bioassays and separations, the monodisperse spheres are composed of...

Liquid handling platform. (New Products).
April 1, 2003... Sciclone ALH 3000 aspirates and dispenses in 96, 384, and 1536 well formats. System updates include Sciclone Software (V3.0) instrument control program. System integrators and assay developers will benefit from the intuitive graphical user...

Transgenic support services. (New Products).
April 1, 2003... Harlan transgenic support services include breeding and shipping specific models when required, or maintaining animals shipped to us as an exclusive colony in isolators animals to be delivered as needed. Strict confidentiality is maintained...

Flexible butyl rubber hose. (New Products).
April 1, 2003... APBWF hose is offered for high purity applications in which flexibility is important. With a smooth, odorless, white chlorobutyl rubber core, the hose is suitable for a wide variety of applications. Features include FDA-sanctioned ingredients,...

Color digital camera. (New Products).
April 1, 2003... Insight 3-Shot color digital camera offers high-resolution qualitative capture of brightfield and bright fluorescence images. This camera uses a liquid crystal filter to measure red, green and blue at every pixel location. The system utilizes a...

SiRNA transfection reagent. (New Products).
April 1, 2003... GeneEraser[TM] siRNA transfection reagent has demonstrated high transfection efficiency of siRNA in a variety of mammalian cell lines, as well as reduced levels of cell damage. Supplied in a single, ready-to-use vial, the reagent and the siRNA...

Chromatography data handling software. (New Products).
April 1, 2003... EZStart[TM] Software chromatography software provides software control of LC or GC instruments as well as control of data acquisition, data processing, postrun analysis, and reporting. Software wizards guide users to create methods and...

96-Well Plate line. (New Products).
April 1, 2003... The NUNC DeepWell Plate line now includes both sterile and non-sterile versions in 1 ml and 2 ml capacities. Molded of chemically resistant polypropylene, the plates have cylindrical round bottom well configurations in a standard 96-well...

Electrophoresis Power Supplies. (New Products).
April 1, 2003... Power Station Electrophoresis Power Supplies are microprocessor-controlled units with four sets of output terminals. Output can be set for constant voltage or constant current with automatic crossover. Digital timer can be set fro periods from...

Muli-element probe for ultrasonic liquid processing. (New Products).
April 1, 2003... Multi-element ultrasonic liquid processing probe takes the place of standard 20 kHz probe and processes four (250 ml-10 ml) samples simultaneously. The probe consists of a four-element coupler and four 3 mm stepped microtips. The energy...

Recombinant Human NKG2D/Fc Chimera. (New Products).
April 1, 2003... Recombinant Human NKG2D/Fc Chimera and MICA/Fc Chimera MICA (MHC class I chain-related gene A) are transmembrane glycoproteins that function as a ligand for human NKG2D, a type II transmembrane glycoprotein containing an extracellular...

Reagents for investigation of DNA damage. (New Products).
April 1, 2003... Rockland Immunochemicals has developed a series of phospho specific antibodies to ATM protein kinase. ATM, the gene mutated in the hereditary disease ataxia-telangiectasia, codes for a protein kinase that acts as a master regulator of cellular...

Ultra/microcentrifuges. (New Products).
April 1, 2003... SORVALL[R] Discovery[TM] SE floor model ultracentrifuges and micro-ultracentrifuges offer top speeds of 100,000 rpm. Operator interface includes an intuitive keypad and large LCD, for easy set-up of routine spins and access to advanced...

Antibody labeling kits. (New Products).
April 1, 2003... Zenon[TM] antibody-labeling kits, for use with mouse Ig[G.sub.2a], mouse Ig[G.sub.2b], and rabbit IgG primary antibodies, provide a fast, versatile and reliable method for producing antibody conjugates, even with very small (sub-microgram)...

Stealth 3 pins and corresponding microarrays. (Microarrays).
April 1, 2003... (Top panel) SMP3 Pin with a regular uptake channel (top left), an SMP3B Pin with a "bubble" uptake channel (top center), and an SMP3XB Pin with an "extended bubble" channel (top right). The SMP3, SMP3B and SMP3XB pins load 0.25 [micro]l, 0.60...

Array supplies, scanners, services. (Microarrays).
April 1, 2003... Sunergia Medical offers robust and flexible high-throughput genotyping services and products for genome-wide mutation and SNP detection and re-sequencing based on APEX technology through custom genotyping service and technology transfer....

Mouse genome array. (Microarrays).
April 1, 2003... CodeLink[TM] UniSet Mouse 1 Bioarray contains DNA probes spotted onto a specially prepared glass slide, with each probe representing one of about 10,000 mouse genes. By adding an RNA sample prepared from mouse tissue to the bioarray, scientists...

Microarray slides. (Microarrays).
April 1, 2003... Vivid[TM] microarray slides are constructed of a glass base with a membrane printing area. Unique membrane construction offers increased surface area and low background. Use of membrane slides as a microarray substrate facilitates high binding...

RNA amplification for array analysis. (Microarrays).
April 1, 2003... The MessageAmp[TM] aRNA Kit selects and amplifies mRNA from a total RNA or poly(A) sample, resulting in a 1000 fold amplification of the RNA target for array analysis. A complete kit based on Eberwine's patented procedure, MessageAmp is...

Ceramic microarray pins. (Microarrays).
April 1, 2003... Apogent Discoveries MicroSpot[TM] C ceramic pins make it easier to print quality microarrays. The ceramic pins are used with the MicroGrid[TM] arrayer to provide improved spot morphology, up to 5 times more spots per source visit, and require...

Tissue microarray system. (Microarrays).
April 1, 2003... Discovery-TMA high-speed automated optical platform and integrated software system is optimized for the acquisition, processing and analysis of images from tissue microarrays. The system brings high content screening technology to tissue...

Array analysis software. (Microarrays).
April 1, 2003... Insightful Corporation's ArrayAnalyzer[TM]. an adaptable microarray analysis module for the S-PLUS[R] data analysis software package, is the result of collaboration with the BioConductor Project, a team of academic researchers in the field of...

Small protein analysis assay. (Microarrays).
April 1, 2003... The Protein 50 LabChip[R] kit, from Agilent Technologies Incorporated and Caliper Technologies Corporation, automates the sizing and quantitation of proteins ranging in size from 5 to 50 kiloDaltons. Used together with the Agilent 2100...

Protein microarray technology. (Microarrays).
April 1, 2003... Versalinx[TM] Protein Microarray Technology, based upon a small molecule, synthetic affinity surface chemistry, expedites the creation of peptide arrays. Peptide arrays allow the efficient screening of large numbers of different peptides in...

Human breast cancer tissue microarrays. (Microarrays).
April 1, 2003... Human breast cancer tissue microarrays (TMA) are offered for high throughput screening of the in situ gene expression for target validation. The arrays may be used for differential gene expression profiling. A variety of tumors and different...

Plastic human 12K microarray. (Microarrays).
April 1, 2003... The Atlas[TM] Plastic Human 12K Microarray contains sequences from nearly 12,000 genes printed in duplicate on a plastic support surface. Like nylon arrays, these plastic microarrays require no special equipment for imaging; like glass arrays,...

Microarray reagent systems. (Microarrays).
April 1, 2003... Corning Incorporated, Life Sciences has introduced Pronto![TM] cDNA and Universal Microarray Reagent Systems for printing and hybridizing cDNA and long oligonucleotide arrays. The systems offer a complete microarray solution from printing...

Array-Ready Oligo Sets. (Microarrays).
April 1, 2003... Qiagen Operon continually develops Array-Rely Oligo Sets[TM] for differential gene expression analysis and now adds the arabidopsis. Candida albicans, Caenorhabditis elegans, and Drosophila melanogaster genomes to its existing product line...

Streptavidin slides for proteome microarrays. (Microarrays).
April 1, 2003... XENOSLIDE series of microscope slides are offered for use in producing proteome microarrays. The XEONSLIDE[TM] S has cavalently attached streptavidin for binding biotin labeled molecules. The slides have high binding capacity, low background...

Cell function genomic arrays. (Microarrays).
April 1, 2003... OriGene[R] SmartArray[TM] gene chips contain pre-selected groups of genes in the form of PCR fragments (400-700 bp). These selected genes are functionally related and are involved in the same regulatory pathway. For example, SmartSet 5 contains...

Genomic arrays, detection system. (Microarrays).
April 1, 2003... The MGX 4D array, based on patented Flow-thru[TM] technology, utilizes a porous substrate constructed of microchannels. Oligonucleotide probes are spotted and bound all along the inner surface of the channels. Hybridization occurs aided by a...

Array analysis software. (Microarrays).
April 1, 2003... VersArray[TM] analysis software features a spot finding and gridding wizard. Functionality includes automatic rotation, grid, subgrid and spot finding in method development for further productivity and convenience. Background subtraction, image...

Rat microarrays. (Microarrays).
April 1, 2003... MWG Biotech offers three Pan[R] arrays--a Rat 10K Array, a Rat 5K Array, and a Rat Liver Array--for investigating one of the most important model organisms in toxicogenomics and life science research. The new 10K Array contains gene-specific...

Cancer antibody array. (Microarrays).
April 1, 2003... Spendlove Research Foundation has refined a miniaturized antibody array system capable of simultaneously quantifying up to 24 different cancer markers within a single well of a microtiter plate using 3-microliters of sample per well. All cancer...

Plate handling and sealing module. (New Products).
April 1, 2003... The PlateServer[TM] module provides automated plate management for assay systems used in drug discovery applications. It performs all operations within an inert environment, maximizing compound integrity and extending compound library life. It...

Vacuum, Prep Tool for genetic analysis workstation. (New Products).
April 1, 2003... Pyrosequencing[TM] Vacuum Prep Tool is available for all of the company's 96-well format genetic analysis systems. The new tool extends the benefits of batch processing 96 post-PCR samples in less than 15 minutes to PSQ[TM]96MA and PSQ[TM]96...

Ephrin antibody sampler pack. (New Products).
April 1, 2003... Zymed Laboratories offers a full line of ephrin and Eph receptor antibodies: polyclonal antibodies against ephrin-A1, -A2, -A4, -B1, and -B3, as well as EphA2, EphA3, EphA4, and EphB4 receptors are all available. The Sampler Pack is an...

Mounting Medium. (New Products).
April 1, 2003... VECTASHIELD[R] HarduSet[TM] Mounting Medium, for fluorescently stained tissue sections and cells, provides protection from photobleaching and fading, and hardens. Handling and storage of mounted sections is easy, and no sealing of coverslips is...

Bottle caps for aggressive fluid transfer. (New Products).
April 1, 2003... Customized inert bottle caps produce a system capable of sparging, filtering and transferring highly aggressive fluids from storage bottles to the inlets of an automated chromatography instrument. The PTFE bottle cap offers one inlet and three...

Granzyme antibodies. (New Products).
April 1, 2003... Granzymes kill by forcing target cells to go into apoptosis. The measurement of granzymes in a variety of clinical conditions may open up new insights in health and disease. Granzymes are exogenous serine proteinases (enzymes) that are released...

SiRNA Expression Vectors. (New Products).
April 1, 2003... The pSilencer[TM] siRNA Expression Vectors with antibiotic selectable markers are for transient and long-term gene silencing studies. These vectors express siRNA within mammalian cells using either a U6 or H 1 polymerase III promoter. Versions...

Continuously adjustable micropipettes. (Pipettors).
April 1, 2003... Accupet continuously adjustable micropipettes, for liquid measurements from 2-20, 20-200 and 100-1000 microliters, feature a DirectVue[TM] Volume Indicator for easy viewing of volume settings during use and optional plunger button volume...

Liquid handling products. (Pipettors).
April 1, 2003... USA Scientific. Inc. offers a full linc of liquid handling products, including pipettors, repeating pipettors, pipet controllers, and disposable tips. Pipettors are available in single and multi-channel styles, for manual or electronic...

Air-displacement pipette. (Pipettors).
April 1, 2003... MiniPet air-displacement micropipette is a cost-effective alternative to bulb pipets, capillaries and traditional laboratory pipets. The product handles thousands of pipette steps using generic disposable tips. The brightly colored...

Pipettes, tips, service. (Pipettors).
April 1, 2003... Brinkmann[TM] Instruments, Incorporated offers the Eppendorf Research[R] Family of Pipettes, which includes fixed-volume, adjustable-volume, and multichannel models as well as the electronic Eppendorf Research pro Pipette. A single system...