Brown University Psychopharmacology Update articles from March 2007

Brown University Psychopharmacology Update archives from March 2007

New medication paliperidone (Invega) approved for treatment of schizophrenia.(Newly Approved Antipsychotic)
March 1, 2007... precis * Newly approved paliperidone (Invega) extended-release (ER) appears to be effective in rapidly controlling symptoms of schizophrenia and improving personal and social functioning; can be used in patients with mild or moderate...

Citalopram shows limited effect on compulsive sexual behavior.(Sexual Dysfunction)(Clinical report)
March 1, 2007... precis * Researchers conducted a preliminary, double-blind, placebo-controlled evaluation of citalopram for treatment of compulsive sexual behavior (CSB) * Twenty-eight men who met the criteria for CSB participated in a 12-week...

Delirium associated with bupropion and fluoxetine.(Drug-Drug Interactions)
March 1, 2007... Bupropion (Wellbutrin, Zyban), an antidepressant chemically unrelated to other currently available antidepressants, has been shown to be effective in the management of treatment resistant depression and smoking cessation. Although it has a...

Quetiapine and quality of life in bipolar depression.(What's New in Research)(Clinical report)
March 1, 2007... In a new report on the effects of quetiapine (Seroquel) on quality of life (QOL) improvements in adults with bipolar depression, Endicott and colleagues write that despite the obvious impact of depressive symptoms on QOL, this aspect of...

IM aripiprazole for agitation in schizophrenia.(What's New in Research)
March 1, 2007... Supporting the results of an earlier dose-ranging study of intramuscular (IM) aripiprazole (Abilify) for acute agitation (Modell et al. 2004), Anrezina and colleagues report that IM aripiprazole is not only safe and effective but appears...

Study examines psychotropic drug use in children with MR.(News Notes)
March 1, 2007... Dutch researchers recently examined patterns of psychopharmacotherapy and the use of specific psychotropic drugs in children and adolescents with mental retardation (MR), with a focus on the factors related to use of specific classes of...

Comparing HAM-D-6 with HAM-D-17.(News Notes)(Brief article)
March 1, 2007... In a recently published report, Danish investigators write that a key factor behind the uncertainty regarding the optimal dose for achieving maximum antidepressant effect of selective serotonin reuptake inhibitors (SSRIs) or...

Hyperglycemia in a child treated with aripiprazole.(Case Report)
March 1, 2007... Patient: 7 years old, male Medications: methylphenidate (Metadate), aripiprazole (Abilify), atomoxetine (Strattera), insulin Case: The authors report the first case to their knowledge of a child developing hyperglycemia following...

Approval: paliperidone for schizophrenia.(From the FDA)(Brief article)
March 1, 2007... On December 20 the FDA approved the first new treatment for schizophrenia since 2003, the atypical antipsychotic Invega (paliperidone) extendedrelease (see story, page 1). Paliperidone is the principal active metabolite of risperidone. It is...

Approval: first generic Wellbutrin XR.(From the FDA)(Brief article)
March 1, 2007... On December 14 the FDA approved the first generic version of Wellbutrin XL (bupropion hydrochloride) Extended Release Tablets, indicated for the treatment of major depressive disorder in adults ages 18 and older. Bupropion Hydrochloride...