Clinical and Investigative Medicine articles from December 2004

Clinical and Investigative Medicine archives from December 2004

The Canadian Clinical Research Initiative: transforming Canadian clinical research capacity.(Editor's Page)(Editorial)
December 1, 2004... The accelerating pace of discovery in basic biomedical research produces an avalanche of new knowledge about the human body and its functions, from the human genome, to basic molecular and cellular processes, to the mechanisms of health and...

Canadian Society for Clinical Investigation's Young Investigator Awards: the 2004 winners.(News And Newsmakers)
December 1, 2004... Rohit Bose is in year 6 of the MD/PhD program at the University of Toronto. He is working in Dr. Jeff Wrana's lab at the Samuel Lunenfeld Research Institute at Mount Sinai Hospital, studying the role of tumour-secreted transforming growth...

Waiting time in relation to wait-list size at registration: statistical analysis of a waiting-list registry.(Original Research)
December 1, 2004... Abstract Objective: To examine the relationship between the length of a waiting list for elective vascular surgery and the delay before undergoing the operation. Methods: We undertook a prospective cohort study of patients registered on...

8-Isoprostaglandin F2 alpha: a potential index of lipid peroxidation in systemic lupus erythematosus.(Original Research)
December 1, 2004... Abstract Background: Lipid peroxidation is a central feature of oxidant injury that leads to the vascular disease associated with systemic lupus erythematosus (SLE). In the past, lipid peroxidation has been difficult to measure. Because...

Assessment of the information needs and use of information resources on complementary and alternative medicine by Alberta family physicians.(Original Research)
December 1, 2004... Abstract Background: The public's increasing use of complementary and alternative medicine (CAM) poses unique challenges for primary care physicians in knowledge and patient communication. The objective of our study was to assess Alberta...

A study of warning letters issued to institutional review boards by the United States Food and Drug Administration.(Original Research)
December 1, 2004... Abstract Purpose: This study explores the ethical issues contained in warning letters (WLs) issued to institutional review boards (IRBs) by the United States Food and Drug Administration (FDA). Methods: The online FDA Warning Letter Index...

Dissecting the "end game": clinical relevance, molecular mechanisms and laboratory assessment of apoptosis.
December 1, 2004... Abstract Background: Apoptosis, the process of cell death, is a complex subject. In this review we highlight recent developments in the regulation and dysregulation of apoptosis in health and disease and summarize common laboratory...