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Glyceraldehyde-3-phosphate dehydrogenase as a target for small-molecule disease-modifying therapies in human neurodegenerative disorders.(Commentary/Commentaire)
September 1, 2004... Recent articles have highlighted numerous additional functions of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) that are independent of its well-documented glycolytic function. One of the most intriguing of these functions is as an initiator...
Implication des genes du syteme serotoninergique dans la vulnerabilite aux conduites suicidaires.(Review Paper/Examen cretique)
September 1, 2004... Les conduites suicidaires (CS) sont de determinisme complexe et multi-factoriel. Au sein des nombreux facteurs de risque qui ont ete identifies, les etudes de genetique epidemiologique (etudes familiales, de jumeaux et d'adoption) suggerent...
Mother to infant or infant to mother? Reciprocal regulation of responsiveness to stress in rodents and the implications for humans.(Review Paper/Examen cretique)
September 1, 2004... Optimal early development in most species is dependent upon a stable relationship between the mother and her infant. The research described here focuses on the reciprocal nature of this dyad in rodents and humans, with respect to the regulation...
Peripheral thyroid hormones and response to selective serotonin reuptake inhibitors.(Research Paper/Article de recherche)
September 1, 2004... Objective: To examine the relation between baseline measurements of thyroid function and response to selective serotonin reuptake inhibitors (SSRIs) and to consider the effect of these antidepressants on thyroid hormone levels. Methods:...
American Psychiatric Association honours founding member of the Canadian College of Neuropsychopharmacology.(CCNP News and Views\Nouvelles et opinions du CCNP)(Brief Article)
September 1, 2004... The Canadian College of Neuropsychopharmacology (CCNP) and the editorial board of the Journal of Psychiatry & Neuroscience (JPN) are proud to announce that Dr. Yvon D. Lapierre, Editor Emeritus of the journal and founding member of the CCNP,...
Psychopharmacology for the clinician/psychopharmacologie pratique.(Letter to the Editor)
September 1, 2004... To submit questions for this regular feature, please send them to the Journal of Psychiatry & Neuroscience / Revue de psychiatrie & de neuroscience, Canadian Medical Association, 1867 Alta Vista Dr., Ottawa ON K1G 3Y6, Canada; fax 613 729-9545;...
Ethical conduct of journal editors.(Editorial)(Editorial)
September 1, 2004... During the past decade, there has been increasing concern about scientific misconduct. Using the keyword "misconduct," the number of articles retrieved on MEDLINE averaged 100 per year for the decade 1993-2002 compared with an average of 28 per...