Journal of Psychiatry and Neuroscience articles from May 2009

Journal of Psychiatry and Neuroscience archives from May 2009

Moving past the "neuroncentric" perspective: a role for glia in neuropsychiatric disorders.(Editorial)(Report)
May 1, 2009... The development of neuropsychiatric disorders involves an array of different underlying mechanisms, many of which remain at the level of hypotheses and thus the centre of much debate. These mechanisms range from subtle changes in neurochemistry...

Influence of androgen receptor repeat polymorphisms on personality traits in men.(Research Paper/Article de recherche)(Report)
May 1, 2009... Introduction Testosterone influences the structure and function of the brain, both during development and in the adult organism, and is a key factor for the sexual differentiation of this organ. (1,2) Given this influence, it is reasonable...

Emotional learning during dissociative states in borderline personality disorder.(Research Paper/Article de recherche)(Clinical report)
May 1, 2009... Introduction Neurobiological findings (1-9) and clinical data (10,11) suggest that conditioning processes are inhibited by dissociation. Regarding neurobiological processes, the corticolimbic disconnection model of dissociation (12)...

Effects of sustained serotonin reuptake inhibition on the firing of dopamine neurons in the rat ventral tegmental area.(Research Paper/Article de recherche)(Report)
May 1, 2009... Introduction Selective serotonin (5-HT) reuptake inhibitors (SSRIs) are used as first-line drugs in the treatment of depression. However, only about one-third of depressed patients achieve remission within the first medication trial with...

Effects of gut microbiota on the brain: implications for psychiatry.(Commentary/Commentaire)(Report)
May 1, 2009... It may be surprising to learn that the human gastrointestinal tract is home to [10.sup.14] bacterial organisms. (1) In fact, there are more bacteria in the gut than there are somatic cells in the body. These resident bacteria are referred to as...

Dimethylated lysine 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures.(Brief Report/Rapport sommaire)(Report)
May 1, 2009... Introduction The efficient regulation of promoter activity is largely dependent on the coordinate assembly of multiple regulatory proteins. The signals required to focus this assembly on a given promoter at a precise time emanates from...

Treatment of comorbid tobacco use in people with serious mental illness.(Psychopharmacology for the Clinician/Psychopharmacologie pratique)(Report)
May 1, 2009... The information in this column is not intended as a definitive treatment strategy but as a suggested approach for clinicians treating patients with similar histories. Individual cases may vary and should be evaluated carefully before treatment...