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Is bipolar disorder a mitochondrial disease?(Editorial Editorial)(Disease/Disorder overview)(Editorial)
May 1, 2007... While we continue to refine our understanding of the pathophysiology of bipolar disorder (BD), a considerable distance remains before we establish a complete picture of the relevant processes and pathways that result in this illness. Recently,...
Neuroimaging and genetics of borderline personality disorder: a review.(Disease/Disorder overview)
May 1, 2007... Borderline personality disorder (BPD) is a highly prevalent psychiatric disorder that carries a severe risk factor for adolescent and young adult suicide. Relatively little research has examined its biological etiology. Differences in the...
Monoamine oxidase-A polymorphisms might modify the association between the dopamine [D.sub.2] receptor gene and alcohol dependence.
May 1, 2007... Objective: Low monoamine oxidase (MAO) activity and the neurotransmitter dopamine are 2 important factors in the development of alcohol dependence. MAO is an important enzyme associated with the metabolism of biogenic amines. Therefore, the...
The Jock Cleghorn Prize.
May 1, 2007... This prize, which will consist of a cheque for $500, will be awarded by the CCNP for the best poster presentation by a research trainee (graduate student or clinical resident) at the Annual Meeting of the CCNP. All trainees/students who submit...
Electroconvulsive shock enhances striatal dopamine [D.sub.1] and [D.sub.3] receptor binding and improves motor performance in 6-OHDA-lesioned rats.(Research Paper Article de recherche)
May 1, 2007... Objective: Electroconvulsive therapy (ECT) is a widely used and effective treatment for mood disorders and appears to have positive effects on the motor symptoms of Parkinson's disease (PD), improving motor function for several weeks. Because...
Neuron somal size is decreased in the lateral amygdalar nucleus of subjects with bipolar disorder.
May 1, 2007... Objective: Morphometric studies of postmortem brains from subjects with mood disorders have reported altered density of glial cells in the amygdala; however, the nuclear regions have not been examined individually. Methods: We assessed the size...
L-Tyrosine to alleviate the effects of stress?
May 1, 2007... Stress is an inescapable part of human existence and in extreme forms can cause or exacerbate psychiatric disorders, including depression, schizophrenia and posttraumatic stress disorder. Many people feel that their level of stress is above the...
An event-related functional MRI study of working memory in euthymic bipolar disorder.(Research paper/Article de recherche)
May 1, 2007... Objective: Bipolar disorder (BD) is emerging as an illness marred by neurocognitive deficits, many of which do not resolve on recovery. Deficits affecting working memory (WM) in particular appear to be significant. WM comprises temporally...