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The rational use of medications in acute psychotic presentations--the case for less is more.(Psychopharmacology for the Clinician/Psychopharmacologie pratique)
May 1, 2006... A 22-year-old man was brought to the emergency department of a general hospital by his mother, because his behaviour had become progressively inappropriate. He was loud, verbally aggressive and stayed awake all night writing copious musical...
A rant against jargon and neologisms.(Editorial)(psychiatric research)(Editorial)
May 1, 2006... Shortly before he retired, Richard Smith, the editor for many years of BMJ, started an editorial with the statement "Today I'm in old fart mode." (1) I am grateful to him for having set the precedent, because today I am definitely in old fart...
Schizophrenia: an integrative approach to modelling a complex disorder.(Review Paper/Examen critique)(psychiatric research)
May 1, 2006... The discovery of candidate susceptibility genes for schizophrenia and the generation of mice lacking proteins that reproduce biochemical processes that are disrupted in this mental illness offer unprecedented opportunities for improved...
The search for new off-label indications for antidepressant, antianxiety, antipsychotic and anticonvulsant drugs.(Review Paper/Examen critique)(psychiatric research)(2004 CCNP Heinz Lehmann Award paper)
May 1, 2006... 2004 CCNP Heinz Lehmann Award Paper: Part I
Most drugs are prescribed for several illnesses, but it took several years for psychotropic drugs to have multiple clinical indications. Our search for serotonergic drugs in affective illnesses...
Interrelations between psychiatric symptoms and drug-induced movement disorder.(2004 CCNP Heinz Lehmann Award paper)
May 1, 2006... 2004 CCNP Heinz Lehmann Award Paper: Part II
After 30 years of clinical research into drug-induced movement disorder (DIMD), we are still facing unresolved issues regarding the interrelations between psychiatric symptoms and DIMD. Recently,...
"Missing links" in borderline personality disorder: loss of neural synchrony relates to lack of emotion regulation and impulse control.(Research Paper/Article de recherche)(psychiatric research)
May 1, 2006... Objective: Symptoms of borderline personality disorder (BPD) may reflect distinct breakdowns in the integration of posterior and frontal brain networks. We used a high temporal resolution measure (40-Hz gamma phase synchrony) of brain activity...
Downregulation in components of the mitochondrial electron transport chain in the postmortem frontal cortex of subjects with bipolar disorder.(Research Paper/Article de recherche)(psychiatric research)(includes statistical tables)
May 1, 2006... Objective: Many studies indicate a genetic predisposition to bipolar disorder (BD) and suggest that a number of abnormal genes are involved in its development. In this study, we used DNA microarray technology to analyze gene-expression profiles...
Canadian College of Neuropsychpharmacology/College canadien de neuropsychopharmacologie.(CCNP News and Views/Nouvelles et opinions du CCP)
May 1, 2006... 2006 Award Winners
Heinz Lehmann Award
Dr. L. Trevor Young is the recipient of the 2006 Canadian College of Neuropsychopharmacology (CCNP) Heinz Lehmann Award. Dr. Young is a Professor in the Department of Psychiatry at the University...