Journal of Psychiatry and Neuroscience articles from May 2005

Journal of Psychiatry and Neuroscience archives from May 2005

Loudness dependence of the auditory evoked potential and response to antidepressants in Chinese patients with major depression.(Research Paper/Article de recherche)
May 1, 2005... Objective: To investigate the loudness dependence of the auditory evoked potential (LDAEP) in predicting response to treatment for major depression. Methods: One hundred patients of Chinese ethnicity with major depression were divided into 2...

Universities, governments and industry: can the essential nature of universities survive the drive to commercialize?(Editorial)(Editorial)
May 1, 2005... Having spent 40 years in universities, I have had sufficient time to consider some of the idiosyncrasies, foibles and problems of these academic institutions. The purpose of this editorial is to discuss the current state of university research...

Selective GABAergic treatment for panic? Investigations in experimental panic induction and panic disorder.
May 1, 2005... [gamma]-Aminobutyric acid (GABA) is the most important inhibitory neurotransmitter in the central nervous system (CNS). It exerts its rapid inhibitory action mostly through [GABA.sub.A] receptors, which are targets for benzodiazepines,...

Is the cerebellum relevant in the circuitry of neuropsychiatric disorders?
May 1, 2005... Contemporary mechanistic models of several psychiatric disorders propose abnormalities in the structure and function of distinct neural networks. The cerebellum has both anatomic and functional connections to the prefrontal cortex, the...

Comorbidity and pathophysiology of obsessive-compulsive disorder in schizophrenia: is there evidence for a schizo-obsessive subtype of schizophrenia?
May 1, 2005... Epidemiologic and neurobiologic evidence suggests that patients with comorbid obsessive-compulsive disorder (OCD) and schizophrenia may represent a special category among patients with schizophrenia. Efforts to examine the neurobiology of this...

Amitriptyline and fluoxetine protect PC12 cells from cell death induced by hydrogen peroxide.(Research Paper/Article de recherche)
May 1, 2005... Objective: To investigate the potential protective effects of amitriptyline and fluoxetine in a catecholamine cell model. Methods: Cultured rat pheochromocytoma (PC12) cells were pretreated with amitriptyline or fluoxetine for 24 or 48 hours...

What are the treatment options for comorbid alcohol abuse and depressive disorders?(Psychopharmacology for the Clinician/Psychopharmacologie pratique)
May 1, 2005... Alcohol, probably one of the oldest mood-enhancing drugs discovered by humans, can induce depression. Levels of serotonin (5-HT) and its metabolites are low in some brain regions of alcohol-preferring rats and in the cerebrospinal fluid of...