Journal of Psychiatry and Neuroscience articles from March 2008

Journal of Psychiatry and Neuroscience archives from March 2008

Implication of the polyamine system in mental disorders.(Review Paper
March 1, 2008... The polyamine pathway has an essential role in many cellular functions and has been implicated in several pathological conditions. Accumulating evidence suggests that the polyamine system also plays a role in the etiology and pathology of...

The auditory-visual integration of anger is impaired in alcoholism: an event-related potentials study.(Research Paper / Article de recherche)(Clinical report)
March 1, 2008... Objectives: Chronic alcoholism leads to impaired visual and auditory processing of emotions, but the cross-modal (auditory-visual) processing of emotional stimuli has not yet been explored. Our objectives were to describe the...

Serotonin transporter genotype interacts with paroxetine plasma levels to influence depression treatment response in geriatric patients.(Research Paper / Article de recherche)(Clinical report)
March 1, 2008... Objective: To investigate whether variable antidepressant response may be influenced by an interaction between the serotonin transporter promoter polymorphism (5-HTTLPR) and antidepressant concentration. Methods: Elderly subjects with...

Serotonin receptor subtype and p11 mRNA expression in stress-relevant brain regions of suicide and control subjects.(Research Paper / Article de recherche)(Report)
March 1, 2008... Objective: Studies comparing people suffering from depression who commited suicide with control subjects have yielded inconsistent results regarding serotonin (5-HT) involvement in pathology, possibly owing to procedural factors. Our objective...

Rostral anterior cingulate volume predicts treatment response to cognitive-behavioural therapy for posttraumatic stress disorder.(Clinical report)
March 1, 2008... Objective: To index the extent to which treatment response in posttraumatic stress disorder (PTSD) is predicted by rostral anterior cingulate cortex (rACC) volume. Method: We used structural magnetic resonance imaging in a 1.5 T scanner to...

Psychopharmacology for the Clinician / Psychopharmacologie pratique.(Clinical report)
March 1, 2008... The information in this column is not intended as a definitive treatment strategy but as a suggested approach for clinicians treating patients with similar histories. Individual cases may vary and should be evaluated carefully before treatment...

Do antidepressants really work?(Editorial)
March 1, 2008... In the Jan. 17, 2008, issue of the New England Journal of Medicine, a "special article" described the selective publication of antidepressant trials and its influence on the apparent efficacy of such medications. (1) It was shown that 22 of the...

Reduced subgenual cingulate volumes in mood disorders: a meta-analysis.(Disease/Disorder overview)
March 1, 2008... Objective: Converging evidence suggests that the subgenual cingulate (SGC) is implicated in regulation of mood and in the pathophysiology of mood disorders. Our objective was to carry out the first meta-analysis of SGC volumes in patients with...