Journal of Psychiatry and Neuroscience articles from March 2007

Journal of Psychiatry and Neuroscience archives from March 2007

NMDA neurotransmission as a critical mediator of borderline personality disorder.(psychiatric research)(Introduction also in French)(includes tables)
March 1, 2007... Studies of the neurobehavioural components of borderline personality disorder (BPD) have shown that symptoms and behaviours of BPD are partly associated with disruptions in basic neurocognitive processes, in particular, in the executive...

Neurocognitive function in an extended Afrikaner-ancestry family with affective illness.(Brief report / Rapport sommaire)(Objective also in French)(Clinical report)
March 1, 2007... Objective: To characterize the neuropsychological profile of an extended family with unipolar depression (UPD) and other forms of affective illness. Method: We administered a battery of neuropsychological tasks measuring various aspects of...

Lack of association between the norepinephrine transporter gene and major depression in a Han Chinese population.(Research Paper / Article de recherche)(Objective also in French)(includes statistical tables)(Clinical report)
March 1, 2007... Objective: Although the physiological mechanisms contributing to the development of major depression remain unclear, several lines of evidence suggest that the catecholaminergic system involving the norepinephrine transporter (NET) is...

Mood-elevating effects of d-amphetamine and incentive salience: the effect of acute dopamine precursor depletion.(Research Paper/Article de recherche)(includes statistical table)(Objective also in French)(Clinical report)
March 1, 2007... Objective: Midbrain dopamine transmission is thought to regulate responses to rewarding drugs and drug-paired stimuli; however, the exact contribution, particularly in humans, remains unclear. In the present study, we tested whether decreasing...

Onset of confusion in the context of late-life depression.(Psychopharmacology for the Clinician / Psychopharmacologie pratique)
March 1, 2007... A 70-year-old woman with a long history of mood disorder presented to her psychiatrist complaining of increasing confusion. She had a history of recurrent depression since her mid-thirties and had been on and off various antidepressant drugs....

Folate and depression--a neglected problem.(Editorial)(psychiatric research)(Editorial)
March 1, 2007... Researchers are not immune to fashion. A wealth of data going back several decades relating serotonin function to the regulation of mood and the current emphasis on genetics in biological psychiatry research have resulted in an increasing...

In memoriam--Guy Debonnel, MD, CSPQ (1949-2006).(CCNP News and Views Nouvelles et opinions du CCNP)(Obituary)
March 1, 2007... Dr. Guy Debonnel passed away unexpectedly at his home in Montreal on November 4, 2006. The loss of this accomplished clinician-scientist at 57 years of age leaves an important gap in the Canadian neuroscience community. Dr. Debonnel was one of...

Imaging the serotonin transporter during major depressive disorder and antidepressant treatment.(psychiatric research)(Introduction also in French)(includes statistical tables)
March 1, 2007... 2005 CCNP Young Investigator Award Paper This paper focuses on serotonin transporter 5-HTT imaging to investigate major depressive disorder (MDD) and antidepressant occupancy. Such investigations have only recently been possible as a...