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Advances in neurobiology, assessment and treatment of female-specific mood disorders: papers from a symposium presented at the joint congress of the Collegium Internationale Neuro-Psychopharmacologicum and the Canadian College of Neuropsychopharmacology, Chicago, July 11, 2006.(Editorial)(Clinical report)
July 1, 2008... Depression is currently one of the leading causes of disability on the global burden of disease list worldwide and is predicted to rank second by the year 2020. (1) The morbidity associated with mood disorders in women is even greater. Not only...
Premenstrual dysphoric disorder: burden of illness and treatment update.(Disease/Disorder overview)
July 1, 2008... Five percent of menstruating women have severe premenstrual symptoms and impairment of functioning defined as premenstrual dysphoric disorder (PMDD). Clinically significant premenstrual symptoms occur in at least an additional 20% of...
Perinatal depression: treatment options and dilemmas.(Disease/Disorder overview)
July 1, 2008... The treatment of depression during pregnancy and the postpartum period raises unique concerns about safety for the developing fetus and the infant. An increasing number of studies suggest adverse effects from untreated stress, anxiety and...
Sex steroid-related candidate genes in psychiatric disorders.(Clinical report)
July 1, 2008... Sex steroids readily pass the blood-brain barrier, and receptors for them are abundant in brain areas important for the regulation of emotions, cognition and behaviour. Animal experiments have revealed both important early effects of these...
Reproductive hormone sensitivity and risk for depression across the female life cycle: a continuum of vulnerability?(Clinical report)
July 1, 2008... Throughout most of their lives, women are at greater risk for depression than men. Hormones and neurotransmitters share common pathways and receptor sites in areas of the brain linked to mood, particularly through the hypothalamic-pituitary-...
Short telomeres in patients with chronic schizophrenia who show a poor response to treatment.(Correction)(Correction notice)
July 1, 2008... In the print and online versions of the article by Wu-Yang Yu, Hsueh-Wen Chang, Ching-Hua Lin and Chung-Lung Cho (JPN 2008;33[3]:244-7]), the contributors' information stated in error that Drs. Yu and Cho contributed equally to the work. The...
A new, female-specific irritability rating scale.(Research Paper/Article de recherche)(Clinical report)
July 1, 2008... Objective: Irritability is a prominent symptom in the spectrum of female-specific mood disorders, and in some women, irritability is serious enough to disrupt their lives and warrant treatment. The objective of this research was to develop a...
Canadian College of Neuropsychopharmacology/College canadien de neuropsychopharmacologie: 2008 award winners.(CCNP News and Views/Nouvelles et opinions du CCNP)
July 1, 2008... Heinz Lehmann Award
Dr. William Honer is the recipient of the 2008 Canadian College of Neuropsychopharmacology (CCNP) Heinz Lehmann Award. Dr. Honer is a Professor of Psychiatry at the University of British Columbia and a Jack Bell Chair...
Treating depression during pregnancy.(Psychopharmacology for the Clinician/Psychopharmacologie pratique)(Clinical report)
July 1, 2008... The information in this column is not intended as a definitive treatment strategy but as a suggested approach for clinicians treating patients with similar histories. Individual cases may vary and should be evaluated carefully before treatment...