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Pregnancy, depression, antidepressants and breast-feeding.(Editorial)(psychiatric research)
July 1, 2006... "Pregnancy protects against depression." This is a common belief, perhaps based in part on some women experiencing a heightened feeling of emotional well-being during pregnancy. However, the evidence indicates otherwise. In particular,...
Correction.(Correction notice)
July 1, 2006... The following article should have been cited as reference 16 instead of the article that is currently cited in a recent Journal of Psychiatry and Neuroscience article by Sidney H. Kennedy, Henning F. Andersen and Raymond W. Lam (Efficacy of...
The role of neurotensin in central nervous system pathophysiology: what is the evidence?(psychiatric research)
July 1, 2006... The peptide neurotensin has been studied for more than 30 years. Although it is widely distributed in the central and peripheral nervous systems, neurotensin has been more intensely studied with regard to its interactions with the central...
The effect of lithium on the adrenoceptor-mediated second messenger system in the rat brain.(Research Paper)(psychiatric research)(includes statistical tables)
July 1, 2006... Objective: Lithium remains the most widely used treatment for bipolar disorder; however, the molecular mechanisms underlying its therapeutic actions have not been fully elucidated. We studied the in-vivo effect of lithium on the density of...
Social behaviour and mood in everyday life: the effects of tryptophan in quarrelsome individuals.(Research Paper)(psychiatric research)(includes statistical table)
July 1, 2006... Objective: We hypothesized that increasing brain serotonin in healthy individuals with high scores on 2 self-report measures of trait quarrelsomeness would reduce quarrelsome behaviours and enhance agreeable behaviours when measured...
Increased olfactory sensitivity in euthymic patients with bipolar disorder with event-related episodes compared with patients with bipolar disorder without such episodes.(Research Paper)(psychiatric research)(includes statistical tables)
July 1, 2006... Objective: Some patients with bipolar disorder experience mood episodes following emotional life events, whereas others do not. There is evidence that orbitofrontal hypoactivity may be related to this, because the orbitofrontal cortex is...
Levomepromazine versus chlorpromazine in treatment-resistant schizophrenia: a double-blind randomized trial.(Research Paper)(psychiatric research)(includes statistical tables)
July 1, 2006... Objective: We compared the effect of levomepromazine (LMP) with chlorpromazine (CPZ) in treatment-resistant schizophrenia (TRS). Methods: We carried out a double-blind, parallel group study (n= 19/arm) with balanced randomization in blocks of 4...
Treating depression with selective norepinephrine reuptake inhibitors:.(Psychopharmacology for the Clinician Psychopharmacologie pratique)
July 1, 2006... Mr. A is 55-year-old patient with depression who only had a partial response to bupropion, 300 mg/d. Upon referral, his symptoms were of moderate intensity (Hamilton 17-item scale: 23), and he was not taking any antidepressants. He was randomly...