Journal of Psychiatry and Neuroscience articles from July 2005

Journal of Psychiatry and Neuroscience archives from July 2005

On the selection and use of atypical antipsychotics in the management of nonpsychotic mood and anxiety disorders.(Psychopharmacology for the Clinician/Psychopharmacologie pratique)
July 1, 2005... A female patient in her late 20s had suffered from severe obsessive-compulsive disorder from childhood. Her obsessions were mainly about the contamination of her apartment on her return from public places. She carried out cleaning rituals that...

Evidence for the activity of lamotrigine at 5-H[T.sub.1A] receptors in the mouse forced swimming test.(Research Paper/Article de recherche)
July 1, 2005... Background: The antiepileptic drug lamotrigine is effective in the treatment of focal epilepsies. It is thought to act by inhibition of glutamate release through blockade of voltage-sensitive sodium channels and stabilization of the neuronal...

Responsiveness of 5-H[T.sub.1A] and 5-H[T.sub.2] receptors in the rat orbitofrontal cortex after long-term serotonin reuptake inhibition.(Research Paper/Article de recherche)
July 1, 2005... Background: The only antidepressant drugs that are effective in the treatment of obsessive-compulsive disorder (OCD) are those that effectively block the reuptake of serotonin (5-hydroxytryptamine; 5-HT). In humans, positron emission tomography...

Chromatin, DNA methylation and neuron gene regulation--the purpose of the package.(Review Paper/Examen critique)
July 1, 2005... The accessibility of cognate binding sites within a gene promoter can be modified by the condensation or relaxation of local chromatin structure. Local chromatin structure is in turn programmed by covalent modifications of cytosine bases in DNA...

Sleep and perinatal mood disorders: a critical review.(Review Paper/Examen critique)
July 1, 2005... Pregnancy and the postpartum period are recognized as times of vulnerability to mood disorders, including postpartum depression and psychosis. Recently, changes in sleep physiology and sleep deprivation have been proposed as having roles in...

Neuropsychiatric manifestations of HIV infection and AIDS.(Review Paper/Examen critique)
July 1, 2005... As the life expectancy of people living with HIV infection has increased (through recent advances in antiretroviral therapy), clinicians have been more likely to encounter neuropsychiatric manifestations of the disease. Some patients present...

In memoriam--Pavel Hrdina, MD, PhD (1929-2005).(CCNP New and Views/Nouvelles et opinions du CCNP)(Obituary)
July 1, 2005... Pavel Hrdina, a founding member of the Canadian College of Neuropsychopharmacology (CCNP) and former Associate Editor of the Journal of Psychiatry & Neuroscience, was born in Uzhorod, Czeckoslovakia (now Slovakia), on Oct. 3, 1929, and passed...

Atypical antipsychotics for mood and anxiety disorders: safe and effective adjuncts?(Editorial)
July 1, 2005... In the past, typical antipsychotic medications were commonly used with antidepressant drugs for the treatment of severe depression accompanied by psychotic symptoms. When the atypical antipsychotics became available, clinicians started to use...