Journal of Psychiatry and Neuroscience articles from January 2009

Journal of Psychiatry and Neuroscience archives from January 2009

Neural synchrony in patients with a first episode of schizophrenia: tracking relations with grey matter and symptom profile.(Researh Paper
January 1, 2009... Introduction The term "schizophrenia" was initially used by Bleuler (1) to refer to a disease process that produces a "splitting of the psychic functions." (2) Recent formulations have also focused on schizophrenia as a syndrome of...

Has the time come for clinical trials on the antidepressant effect of vitamin D?(Editorial)
January 1, 2009... A recent article in the Archives of General Psychiatry again raises the issue of vitamin D and depression. (1) In the largest study to date involving more than 1000 older adults, mean levels of 25-hydroxyvitamin D were significantly lower in...

Genotype over-diagnosis in amygdala responsiveness: affective processing in social anxiety disorder.(Reseach Paper / Article de recherche)(Clinical report)
January 1, 2009... Introduction The amygdala has long been associated with fear reactions and detection of danger signals. (1) Studies in animals and humans have confirmed that the amygdala is a critical structure in Pavlovian fear conditioning and that it...

A comparison of affected and unaffected relatives of patients with bipolar disorder using proton magnetic resonance spectroscopy.(Correction)(Correction notice)
January 1, 2009... In the print version of the article by T. Hajek, D. Bernier, C. Slaney, L. Propper, M. Schmidt, N. Carrey, G. MacQueen, A. Duffy and M. Alda (JPN 2008;33[6]:531-40]), the citations of references 22-36 in the text were incorrect. This affected...

Cascading effects of stressors and inflammatory immune system activation: implications for major depressive disorder.(2008 CCNP Heinz Lehmann Award paper)(Clinical report)
January 1, 2009... Introduction "What's the matter? You don't seem like yourself today." "Yeah. It's nothing. Don't worry about it." "Well, something's definitely bothering you." "I don't know. I'm just sort of feeling low." "Hmm.... Maybe...

A meta-analysis examining clinical predictors of hippocampal volume in patients with major depressive disorder.(Research Paper / Article de recherche)(Clinical report)
January 1, 2009... Introduction A number of factors implicate the hippocampus in the pathogenesis of major depressive disorder (MDD), including the fact that the hippocampus is a highly stress-sensitive brain region (1) and that MDD is a highly...

A new wave in the genetics of psychiatric disorders: the copy number variant tsunami.(Commentary / Commentaire)(Clinical report)
January 1, 2009... Because genes are major determinants of psychiatric disorders, our community is hoping that, as in many other branches of medicine, (1) molecular genetics will lead to important findings that will revolutionize our understanding of these...

High-frequency repetitive transcranial magnetic stimulation to the cerebellum and implicit processing of happy facial expressions.(Brief Report / Rapport sommaire)(Clinical report)
January 1, 2009... Introduction The concept that the cerebellum is implicated in the experience and regulation of emotions and mood was posited more than half a century ago. (1,2) The first empirical report of cerebellar involvement in the experience of...

JPN's top 10 Articles, December 2008 (based on Web views on PubMed Central).(Journal of Psychiatry and Neuroscience )(Brief article)
January 1, 2009... 1. Long-term lithium treatment and thyroid antibodies: a controlled study Baethge et al. J Psychiatry Neurosci 2005;30(6):423-27 2. Hippocampus and amygdala morphology in adults with attention-deficit hyperactivity disorder ...

The 31st Annual Meeting of the Canadian College of Neuropsychopharmacology: Toronto, Ontario, June 6-9, 2008.(CCNP News and Views / Nouvelles et opinions du CCNP)(Conference notes)
January 1, 2009... The 31st Annual Meeting of the Canadian College of Neuropsychopharmacology (CCNP) was held in Toronto, Ontario, June 6-9, 2008. This report summarizes the 3 CCNP award lectures, plenary lecture and 7 symposia. CCNP Heinz Lehmann Award...

Optimal use of antidepressants: When to act?(Psychopharmacology for the Clinician Psychopharmacologie pratique)
January 1, 2009... The information in this column is not intended as a definitive treatment strategy but as a suggested approach for clinicians treating patients with similar histories. Individual cases may vary and should be evaluated carefully before treatment...