Journal of Psychiatry and Neuroscience articles from January 2005

Journal of Psychiatry and Neuroscience archives from January 2005

The effects of nefazodone on women with seasonal affective disorder: clinical and polysomnographic analyses.(Research Paper/Article de recherche)
January 1, 2005... Objective: To outline the clinical and polysomnographic changes induced by nefazodone in patients with seasonal affective disorder. Methods: Twelve patients were enrolled, and 9 of them studied, in an open-label trial with objective and...

Increased occipital delta dipole density in major depressive disorder determined by magnetoencephalography.(Research Paper/Article de recherche)
January 1, 2005... Objective: To test the hypothesis that there is increased low-frequency activity located predominantly in the frontal lobe in patients with major depressive disorder using magnetoencephalography. Methods: We carried out an unmatched or separate...

Is initiation of smoking associated with the prodromal phase of schizophrenia?(Research Paper/Article de recherche)
January 1, 2005... Objective: Although the association between smoking and schizophrenia is well known, little attention has been paid to the time between initiation of smoking and onset of schizophrenia. Our goal was to study this putative temporal relation...

Adult metachromatic leukodystrophy: disorganized schizophrenia-like symptoms and postpartum depression in 2 sisters.(Research Paper/Article de recherche)
January 1, 2005... We describe the cases of 2 sisters with adult metachromatic leukodystrophy (MLD). Whereas one sister presented with disorganized schizophrenia-like symptoms as the initial manifestation of MLD, the other remained symptom free except for a...

Information-processing deficits and cognitive dysfunction in panic disorder.(Research Paper/Article de recherche)
January 1, 2005... Objective: The plasticity of the startle reflex, including prepulse inhibition (PPI) and habituation, provides operational measures of information processing that are abnormal in several neuropsychiatric disorders characterized by deficits in...

The effect of methionine and S-adenosylmethionine on S-adenosylmethionine levels in the rat brain.(Research Paper/Article de recherche)
January 1, 2005... Objective: S-Adenosylmethionine (SAMe) is a major methyl donor in the brain and is also an antidepressant with few reported side effects; however, SAMe is relatively expensive and unstable. Brain SAMe can be increased by giving methionine to...

Preliminary evidence for an association between aggressive and hostile behaviour and 3[alpha],5[alpha]-tetrahydroprogesterone plasma levels in schizophrenia.(Brief Report/Rapport sommaire)
January 1, 2005... Objective: Because it has been suggested that agents acting on the [gamma]-aminobutyric acid-A (GABAA) receptor complex, such as the neuroactive steroid 3[alpha],5[alpha]-tetrahydroprogesterone (3[alpha],5[alpha]-THP), may be biologic...

Object versus spatial visual mental imagery in patients with schizophrenia.(Brief Report/Rapport sommaire)
January 1, 2005... Objective: Recent research has revealed a larger impairment of object perceptual discrimination than of spatial perceptual discrimination in patients with schizophrenia. It has been suggested that mental imagery may share processing systems...

Quetiapine-induced hypothyroidism.(Letter to the Editors/Correspondance)(Letter to the Editor)
January 1, 2005... Quetiapine is an atypical antipsychotic drug with a greater affinity for serotonin-2A receptors than for dopamine-2 receptors. It has a favourable side-effect profile. We report the case of a patient who developed hypothyroidism after...

What is the optimal implementation of bright light therapy for seasonal affective disorder (SAD)?(Psychopharmacology for the Clinician/Psychopharmacologie pratique)
January 1, 2005... The first issue to address when considering light therapy is to identify those patients most likely to benefit from this particular modality. Whereas many patients with mood disorders will report some worsening of symptoms in fall and winter, a...

Depression and multiple sclerosis: a potential way to understand the biology of major depressive illness.(Editorial)(Editorial)
January 1, 2005... It has long been known that a variety of medical disorders may present with depressive symptoms or syndromes and that depression may influence the course of medical disorders. For example, depression is a risk factor for ischemic heart disease...