Journal of Psychiatry and Neuroscience articles

Recent articles from Journal of Psychiatry and Neuroscience

Moving past the "neuroncentric" perspective: a role for glia in neuropsychiatric disorders.(Editorial)(Report)
May 1, 2009... The development of neuropsychiatric disorders involves an array of different underlying mechanisms, many of which remain at the level of hypotheses and thus the centre of much debate. These mechanisms range from subtle changes in neurochemistry (e.g., the monoamine hypothesis of depression)...

Influence of androgen receptor repeat polymorphisms on personality traits in men.(Research Paper/Article de recherche)(Report)
May 1, 2009... Introduction Testosterone influences the structure and function of the brain, both during development and in the adult organism, and is a key factor for the sexual differentiation of this organ. (1,2) Given this influence, it is reasonable to assume that testosterone may be of importance...

Emotional learning during dissociative states in borderline personality disorder.(Research Paper/Article de recherche)(Clinical report)
May 1, 2009... Introduction Neurobiological findings (1-9) and clinical data (10,11) suggest that conditioning processes are inhibited by dissociation. Regarding neurobiological processes, the corticolimbic disconnection model of dissociation (12) hypothesizes that the medial prefrontal cortex inhibits...

Effects of sustained serotonin reuptake inhibition on the firing of dopamine neurons in the rat ventral tegmental area.(Research Paper/Article de recherche)(Report)
May 1, 2009... Introduction Selective serotonin (5-HT) reuptake inhibitors (SSRIs) are used as first-line drugs in the treatment of depression. However, only about one-third of depressed patients achieve remission within the first medication trial with an SSRI. (1) Different possibilities have been...

Effects of gut microbiota on the brain: implications for psychiatry.(Commentary/Commentaire)(Report)
May 1, 2009... It may be surprising to learn that the human gastrointestinal tract is home to [10.sup.14] bacterial organisms. (1) In fact, there are more bacteria in the gut than there are somatic cells in the body. These resident bacteria are referred to as commensal microbiota, and their arrival during...