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Drug Discovery & Technology News back issues
Huntington's Disrupts Brain Mitochondria.(Brief Article)
August 1, 2002... In a study published in the August issue of Nature Neuroscience, J. Timothy Greenamyre, professor, Department of Neurology, Emory University School of Medicine (1440 Clifton Rd., Atlanta, GA 30322; Tel: 404/727-5640, Fax: 404/727-0473), demonstrates how the mutant huntingtin protein, found...
DRUG TARGETS: Drug Resistance Patent Issued.(Paratek Pharmaceuticals Inc.)(Brief Article)
August 1, 2002... Paratek Pharmaceuticals, Inc. (75 Kneeland St., Boston, MA 02211; Tel: 617/275-0040, Fax: 617/275-0039; Website: www.Paratekpharm.com) has announced the issuance of U.S. Patent 6,346,391, entitled "Methods of Reducing Microbial Resistance to Drugs." The patent covers methods for inhibiting...
Thermogenesis May Be Key to Obesity.(Brief Article)
August 1, 2002... A study led by researchers at Beth Israel Deaconess Medical Center (330 Brookline Ave., Boston, MA 02215-5400) offers a new explanation for how the brain makes adjustments to the body's metabolic rate to prevent extra calories from turning into extra pounds. The findings appear in the...
Rat Model of Epilepsy Created.(Brief Article)
August 1, 2002... Blocking the transport of the neurotransmitter glutamate into nerve cells unexpectedly resulted in an animal model of epilepsy. Aware that extra amounts of the messenger can kill brain cells by overstimulating them, Johns Hopkins (5601 Loch Raven Blvd., No. 507, Baltimore, MD 21239-2905;...
BASIC SCIENCE: Lipid Activates Clot Formation.(medical research information)(Brief Article)
August 1, 2002... The lipid phosphatidylserine (PS), a cell membrane component, appears to activate the final step in the process of blood coagulation-the conversion of prothrombin to thrombin, according to research from the University of North Carolina, Chapel Hill (Chapel Hill, NC 27599; Tel: 919/962-2211;...