Life Sciences & Biotechnology Update articles from September 1998

Life Sciences & Biotechnology Update archives from September 1998

ECONOMICS, COST, AND INSURANCE INVOLVED WITH HOME HEALTH CARE
September 1, 1998... This report (from the ABI/Inform Database) concerns home health care and the economy of housing and service choices available to the elderly and disabled. It covers, for example: independent living; assisted independent living; continuing care;...

TRANSLATING HEALTH-CARE RESEARCH INTO ACTION
September 1, 1998... This (American Association of Health Plans) document presents the proceedings of a conference concerning the translation of health-care research into action (1997, New Orleans, LA). The overall objectives for this meeting were to: publicize...

EXAMINATION OF THE EFFECTS OF HOME-BASED EXERCISE IN PATIENTS WITH HEART FAILURE
September 1, 1998... This (University of California) randomized controlled study examines the effects of a 3-month supervised home-based aerobic and strength-training program on functional status, physical fitness, and quality of life in patients with New York Heart...

DIABETIC NEPHROPATHY IN A FAMILY-PRACTICE SETTING
September 1, 1998... This (Colorado Springs Osteopathic Foundation and Family Medicine Center) report concerns diabetic nephropathy in a family-practice setting. Diabetic nephropathy is a well known complication of both insulin-dependent and non-insulin-dependent...

ALTERING THE RESPONSE TO INFECTIONS INDUCED BY SEVERE INJURY: MULTIPLE ORGAN DYSFUNCTION SYNDROME (MODS)
September 1, 1998... This (University of Massachusetts Medical School) report concerns studies involving altering the response to infection induced by severe injury. Multiple organ dysfunction syndrome (MODS) is most frequent in trauma patients, and is a particular...

THE VECTOR-BORNE DISEASE, FILARIASIS, AND ITS ASSOCIATED ENVIRONMENTAL FACTORS
September 1, 1998... This (NASA) report concerns the vector-borne disease, filariasis, and associated environmental factors. Lymphatic filariasis persists as a major cause of clinical morbidity and a significant impediment to socioeconomic development in various...

PEPTIC ULCER DISEASE: PHYSICIANS' PRESCRIPTION PATTERNS FOLLOWING THE 1994 NIH CONSENSUS CONFERENCE ON HELICOBACTOR PYLORI INFECTION
September 1, 1998... This (Medical Technology and Practice Patterns Institute) study evaluates the prescribing patterns of physicians for the treatment of peptic ulcer disease (PUD). Its particular focus is whether recommendations of a Feb. 1994 NIH Consensus...

MEDICAL NUTRITION THERAPY FOR TREATING, CONTROLLING, AND PREVENTING DISEASES
September 1, 1998... This (Army War College) article concerns medical nutrition therapy as a means to treat, control, and prevent diseases. Medical nutrition therapy is a medically necessary and cost-effective means of treating, controlling, and preventing diseases....

RESEARCH ON MILITARY NUTRITION FACTORS LIMITING SOLDIER EFFECTIVENESS
September 1, 1998... This (Louisiana State University) study concerns research involving military nutrition factors limiting soldier effectiveness. To assess, maintain, or improve a soldier's physical/physiological/psychological capability to function effectively...

COGNITIVE HARDINESS AS A PSYCHOLOGICAL CONSTRUCT OF STRESS RESILIENCY
September 1, 1998... This (Air Force Institute of Technology) report concerns the effects of cognitive hardiness on stress, health, performance, and cardiovascular/neuroendocrine function. Cognitive hardiness is a psychological construct of stress resiliency, which...

MEDICAL COSTS AND PRODUCTIVITY LOSSES FROM BACTERIAL FOODBORNE DISEASES
September 1, 1998... This (Economic Research Service) report concerns the costs and productivity losses from bacterial foodborne diseases. Microbial pathogens in food cause an estimated 6.5-33 million cases of human illness, and up to 9,000 deaths, in the U.S. each...

QUALITY OF LIFE FOR TERMINALLY-ILL CANCER PATIENTS
September 1, 1998... This (University of Texas) document is a summary of a dissertation involving a functional assessment of cancer therapy-end of life (FACT-EOL). It assesses the quality of life of cancer patients having a life expectancy of six months or less....

BREAST CANCER DIAGNOSTICS: COMPUTER-AIDED CLASSIFICATION OF MALIGNANT AND BENIGN LESIONS ON MAMMOGRAMS
September 1, 1998... This (University of Michigan) report concerns computer- aided classification of malignant and benign lesions on mammograms. The first year of work involved: (1) database collection for mammograms containing masses and microcalcifications; (2)...

BREAST CARCINOMA INVASION: CELL-MATRIX INTERACTIONS
September 1, 1998... This (New York University Medical Center) report deals with cell-matrix interactions in breast carcinoma invasion. Transgenic mice carrying an activated form of the N-ras oncogene, under the control of the Mammary Tumor Virus Long Terminal Repeat...

IDENTIFYING BREAST CANCER GENES BY LOSS OF HETEROZYGOSITY
September 1, 1998... This (Medical Biology Institute) article concerns work to develop a novel genomic-subtraction method to rapidly identify all chromosomal regions that undergo loss of heterozygosity (LOH) in breast cancer. LOH is a major mechanism in the genomic...

BREAST DEVELOPMENT AND BREAST CANCER: TRANSGENIC ANALYSIS OF THE ROLE OF TRANSCRIPTION FACTOR AP-2
September 1, 1998... This (Yale University) article concerns transgenic analysis of the role of transcription factor AP-2 in breast development and breast cancer. One of the most prevalent alterations involving human breast cancer is overexpression of the c-erbB-2...

TRANSFORMING GROWTH-FACTOR-BETA (TGFB) RECEPTORS IN HUMAN BREAST CANCER
September 1, 1998... This (Yale University) project addresses three fundamental research issues: (1) Do molecular lesions of the genes involved in the TGFB signaling pathway contribute to the origin and/or progression of breast cancer? Changes in these genes are...

MAPPING A BREAST CARCINOMA TUMOR-SUPPRESSOR GENE TO CHROMOSOME 11P15.5
September 1, 1998... Loss of heterozygosity (LOH) on the short arm of chromosome 11 has been demonstrated in many cancers, suggesting the presence of a tumor suppressor gene. A number of studies have narrowed the region showing LOH in breast tumors to l1p15.5. The...

CARCINOGEN-INDUCED MICROENVIRONMENT IN BREAST CANCER: HOW ABNORMAL STROMAL-EPITHELIAL INTERACTIONS AFFECT THE PROGRESSION OF BREAST CANCER CELLS
September 1, 1998... These (University of California) studies address the question of how abnormal stromal-epithelial interactions affect the progression of breast cancer cells. Studies in the mouse mammary gland reveal that ionizing radiation, a known human breast...

HUMAN BREAST CANCER: REPRESENTATIONAL DIFFERENCE ANALYSIS
September 1, 1998... This (Johns Hopkins University) study concerns difference analysis of human breast cancer. The finding of homozygous deletions has been useful in localizing new tumor-suppressor genes and identifying the involvement of known suppressor genes....

USING POLYMERASE CHAIN REACTION (PCR) FOR GENE-BASED DETECTION OF MICROORGANISMS IN ENVIRONMENTAL SAMPLES
September 1, 1998... Contaminating microorganisms pose a serious potential risk to a crew's well being and water system integrity aboard the International Space Station (ISS). This (NASA) report concerns the development of a gene-based microbial monitor that...

TECHNOLOGY TRANSFER IN PHARMACEUTICAL RESEARCH, PRODUCTION, AND MANUFACTURE
September 1, 1998... This report (from the BioBusiness Database) concerns technology transfer in pharmaceuticals. It covers, for example: technology transfer in pharmaceutical research, production, and manufacture; technology transfer using genetic engineering to...

THE DESIGN AND APPLICATION OF BIOSENSORS AND BIOELECTRODES
September 1, 1998... This report (from the BioBusiness Database) concerns the development and use of biosensors and bioelectrodes in the food industry, environmental studies, and the medical field. It covers, among other topics: the sensitivity and specificity of...

THE USE OF ELECTRICITY AND MAGNETISM IN BIOLOGY AND MEDICINE
September 1, 1998... This (Institute of Electrical and Electronics Engineers) document presents abstracts of the papers presented at the Second World Congress for Electricity and Magnetism in Biology and Medicine. It covers four major areas: physical; biological;...

THE RELATIONSHIP BETWEEN APOPTOSIS AND ISCHEMIA
September 1, 1998... This report (from the Life Sciences Collection Database) concerns the imbalance of cell death and survival caused by apoptosis, leading to diseases and ischemic damage. It covers various mechanisms and pathways of apoptosis, including: hypoxia;...

CHLORINE AND CHLORINE DIOXIDE DISINFECTANTS
September 1, 1998... This report (from the Life Sciences Collection Database) concerns the antimicrobial properties of chlorine and chlorine dioxide. It covers, among other related topics: the use of chlorine for the inactivation of viruses, bacteria, and fungi in...

EFFECTS OF FEMALE SEX-HORMONE LEVELS ON THE OSSEOINTEGRATION OF DENTAL IMPLANTS
September 1, 1998... Successful rehabilitation of female service members suffering traumatic injuries to the maxillofacial region is both a physiologic and psychologic issue. This (Dwight David Eisenhower Army Medical Center) report concerns a clinical evaluation to...

THERAPEUTIC USES OF IODINE-131
September 1, 1998... This translation from Austria (International Atomic Energy Agency) presents and discusses the therapeutic uses of Iodine-131, its application, and proper procedures regarding its use. (Order this LIFE SCIENCES & BIOTECHNOLOGY UPDATE reviewed...

RELATIONSHIP BETWEEN LOW LEVELS OF TOXICANTS AND NEUROLOGICAL RESPONSES IN NEONATES
September 1, 1998... Exposure of humans to lethal or clearly harmful levels of toxicants is straightforward to assess. Counting the number of survivors, or enumerating injuries, provides an accurate and repeatable method for assessing toxicant effect. However,...

PROPOSED GUIDELINES FOR CARCINOGEN RISK ASSESSMENT
September 1, 1998... These (EPA) proposed guidelines provide an analytical framework for the incorporation of all relevant biological information, and the recognition of a variety of situations regarding cancer hazard. The guidelines are flexible enough to allow for...