Life Sciences & Biotechnology Update articles from May 2001

Life Sciences & Biotechnology Update archives from May 2001

MODELS OF INTEGRATED LONG-TERM CARE AND RURAL APPLICATIONS.
May 1, 2001... This (University of Kentucky Medical Center) report contains abstracts and an executive summary of a conference (1999) on integrated models of long-term care and rural applications. The conference brought researchers, policy makers, and...

PRIMARY CARE PREVENTIVE-SERVICES DELIVERY AND COMPETING DEMANDS.
May 1, 2001... This (University of Nebraska Medical Center) report addresses preventive-services and competing demands in primary care. Otherwise effective approaches to quality improvement often fail to effect change when implemented in primary care...

HEALTH-CARE WORKFORCE ISSUES, OPTIONS, AND CONSEQUENCES.
May 1, 2001... This (Agency for Health Care Policy and Research) document contains the proceedings of a workshop dealing with health-care workforce issues, options, and consequences (1999, Philadelphia, PA). The workshop was held primarily for state and...

SEARCHING FOR QUALITY IN MEDICAL CARE.
May 1, 2001... This (Maine Medical Assessment Foundation) project is designed to demonstrate the replicability and utility of the study group model -- which had already existed in Maine for many years -- for the effective dissemination of research findings,...

PRIMARY CARE PHYSICIANS PARTICIPATION IN MANAGED CARE.
May 1, 2001... This (University of California) study uses a longitudinal mailed survey of primary care physicians, before and after the expansion of Medicaid managed care in 13 urban California counties, to determine whether the expansion is associated with...

PREVENTION OF WORKER ILLNESS WITHIN THE DOE COMPLEX.
May 1, 2001... This (Oak Ridge National Laboratory) report details the mission to prevent worker illness by fostering outstanding occupational medicine and medical surveillance programs within the DOE complex. It describes the major activities and...

HEALTH ECONOMICS PRINCIPLES FOR DEVELOPING COUNTRIES.
May 1, 2001... This (World Bank Group) volume concerns principles of health economics for developing countries. Health indicators in developing countries have shown significant improvement in the last 50 years. People are living longer, fewer children and...

INVESTMENTS IN HEALTH, NUTRITION, AND POPULATION BY THE WORLD BANK.
May 1, 2001... This (World Bank Group) volume addresses World Bank lending for health, nutrition, and population (HNP), which is accelerating. The Bank's emphasis has evolved from expanding HNP service delivery capacity to encouraging systemic reform. The...

VACCINE ADMINISTRATION BY PHARMACISTS AND THE EFFECTS ON ADULT IMMUNIZATION RATES.
May 1, 2001... This (University of North Carolina) thesis addresses vaccine administration to adults by pharmacists, and the effect on immunization rates. Pneumococcal disease and influenza are still the leading infectious cause of death in America. The...

U.S. NAVY INFECTIOUS DISEASE RATES, 1980-1995.
May 1, 2001... This (Naval Health Research Center) report addresses the infectious disease rates in the U.S, Navy for 1980- 1995. The impact of increasing numbers of women in the Navy, particularly those aboard Navy ships, on infectious disease risk, is...

FETAL ALCOHOL-EXPOSED CHILDREN IDENTIFICATION AND CARE: GUIDE FOR PRIMARY-CARE PROVIDERS.
May 1, 2001... This (National Institute on Alcohol Abuse and Alcoholism) guide for primary-care providers details the identification and care of fetal alcohol-exposed children. Section headings include: (1) What every clinician should know about alcohol use...

INTERRELATIONSHIP BETWEEN THE USE OF ALCOHOL AND OTHER DRUGS.
May 1, 2001... This (American University) report addresses the underlying physiological, sociological, and psychological foundations for prohibiting persons addicted to controlled substances from using alcohol. It addresses the interaction of alcohol with...

SUBSTANCE ABUSE AND MENTAL HEALTH INTERVENTIONS UNDER MANAGED CARE.
May 1, 2001... This (Substance Abuse and Mental Health Services Administration) report addresses preventive interventions under managed care, with respect to mental health and substance abuse. Programs and services that prevent substance abuse and mental...

SUDDEN INFANT DEATH SYNDROME (SIDS).
May 1, 2001... This document from Canada (Canadian Perinatal Surveillance System) addresses sudden infant death syndrome (SIDS), which refers to the sudden and unexpected death of an apparently healthy infant, under one year of age, that remains unexplained...

BENEFITS OF BREASTFEEDING.
May 1, 2001... This document from Canada (Canadian Perinatal Surveillance System) presents information on the benefits of breastfeeding. It also presents selected results from an analysis, by Health Canada, of the "National Population Health Survey" and the...

OCCUPATIONAL AND ENVIRONMENTAL EXPOSURE CORRELATES OF ADVERSE LIVE-BIRTH OUTCOMES.
May 1, 2001... The integration of women into nontraditional military occupations raises questions concerning the impact of such jobs on women's reproductive health. This (Naval Health Research Center) study examines to what extent women in their reproductive...

CARCINO-EMBRYONIC ANTIGEN (CEA): ONE OF THE BEST STUDIED TUMOR MARKERS.
May 1, 2001... This report from Nigeria (University of Ibadan, College of Medicine) addresses the carcino-embryonic antigen. Tumor marker analysis has increased our understanding of the presence of tumors in the body. The carcino-embryonic antigen (CEA) is...

PRACTICING EVIDENCE-BASED ONCOLOGY.
May 1, 2001... This (University of South Florida) document summarizes a symposium on the practice of evidence-based oncology (1999, St. Pete Beach, FL). The symposium was organized with two goals in mind: (1) to teach skills of how to practice evidence-based...

STUDY OF BLACK AND WHITE MEN HAVING A FAMILY HISTORY OF PROSTATE CANCER.
May 1, 2001... This (University of California) study conducts telephone surveys with first-degree relatives of prostate cancer cases, to obtain information on knowledge, behaviors, and psychological distress associated with risk status. In the first year of...

BREAST CANCER PATIENTS SURVEY, METHODOLOGY, AND RESULTS.
May 1, 2001... This (Center for Healthcare Education and Studies) report presents the methodology and a general summary of results of a survey of breast cancer patients. The survey includes all women diagnosed and/or treated for breast cancer (at Brooke...

SUMMARY OF BREAST CANCER DATA EXTRACTED FROM PATIENTS' MEDICAL RECORDS.
May 1, 2001... This (Center for Healthcare Education and Studies) report presents an initial summary of data extracted from the medical records of breast cancer patients surveyed in 1997. The survey includes all women diagnosed and/or treated for breast...

TUMORIGENESIS OF HUMAN BREAST CANCER: THE ROLE OF ESTROGEN RECEPTOR VARIANTS.
May 1, 2001... In order to determine whether differences exist in expression of estrogen receptor (ER) variants mRNA between normal and tumor breast tissues, this research from Canada (Manitoba University) analyzes, by reverse transcription-polymerase chain...

CHARACTERIZATION OF TUBULIN ISOFORMS IN BREAST CANCER.
May 1, 2001... This (University of Texas) work addresses tubulin in breast cancer, which is the major protein of microtubules, the cytoskeletal structures that mediate cell division and is the target for the action of several anti-cancer drugs routinely used...

BREAST CANCER: Fc-GAMMA RECEPTOR TARGETED IMMUNIZATION.
May 1, 2001... Most of the recent progress in tumor vaccines has resulted from: the identification of new tumor antigens and their epitopes; advances in the understanding of the biology of antigen presentation; and delineation of the cell types and functions...

BREAST CANCER: THE ROLE OF Id PROTEINS.
May 1, 2001... This (New York University Medical Center) report addresses the role of Id proteins in breast cancer. The basic helix-loop-helix transcription factors, E12 and E47 (products of the E2A gene), have been implicated to have a role as tumor...

IDENTIFICATION METHODS FOR GENES REGULATED BY ONCOGENIC STIMULI OR DNA DAMAGE.
May 1, 2001... This (Baylor College of Medicine) work develops general methods to identify genes regulated by oncogenic stimuli or DNA damage. The ability of cancer cells to proliferate inappropriately is due the loss of tumor- suppressor genes and gain of...

MAMMOGRAM SCREENING BY AUTOMATED FOLLOWUP.
May 1, 2001... This (Lehigh University) report describes a study aimed at developing a computer-based aid for mammogram screening that makes a detailed comparison between mammograms of the same patient acquired at different screenings and detects changes...

BREAST CANCER METASTASIS AND C-erbB2 RECEPTOR SIGNALING.
May 1, 2001... This (M.D. Anderson Cancer Center) study concerns C-erbB2 receptor signaling and breast cancer metastasis. Overexpression of the c-erbB2 gene is correlated with poor prognosis and the number of lymph node metastases in breast cancer patients....

CLONING AN ETS-RELATED TRANSCRIPTION FACTOR INVOLVED IN A NOVEL EPIGENETIC MECHANISM OF MAMMARY CARCINOGENESIS.
May 1, 2001... This Fred Hutchinson Cancer Research Center) work addresses the cloning of an ETS-related transcription factor involved in a novel epigenetic mechanism of mammary carcinogenesis. Previous studies demonstrate that activating Hrasl mutations,...

BREAST CANCER BIOMARKERS BASED ON NIPPLE AND FINE- NEEDLE ASPIRATES.
May 1, 2001... This (Fox Chase Cancer Center) proposal addresses breast cancer biomarkers based on nipple and fine- needle aspirates. The research has two objectives: (1) to compare the success of experienced vs. inexperienced individuals in collecting...

DEVELOPMENT OF THIN-FILM BATTERY-POWERED TRANSDERMAL MEDICAL DEVICES.
May 1, 2001... This (Oak Ridge National Laboratory) research has led to the development of solid state thin-film rechargeable lithium and lithium-ion batteries. These unique devices can be fabricated in a variety of shapes and to any required size, large or...

USING PRESSURE-ULCER RATES IN DESCRIBING NURSING HOME QUALITY.
May 1, 2001... Assessing and improving the quality of nursing home care remains a priority. Central to this task is the development of risk-adjusted outcome measures that may be used in profiling care. Pressure ulcer development is a particularly important...

SURGEON GENERAL'S REPORT ON ORAL HEALTH IN THE U.S.
May 1, 2001... This (National Institute of Dental and Craniofacial Research) publication is the first Surgeon General's report on oral health, and marks a milestone in the history of oral health in America. The report elaborates on the meaning of oral...

ACUTE RESPIRATORY SITUATION FROM LANDFILL EMISSIONS AND AIR POLLUTION.
May 1, 2001... This (Agency for Toxic Substances and Disease Registry) report addresses a panel study to investigate whether odor and air pollutants emanating from landfills are associated with respiratory health effects among persons diagnosed with asthma....

DEVELOPMENT OF A NEW CLASS OF POLYAMIDE DRUGS THAT CAN SELECTIVELY INHIBIT THE ABERRANT REGULATION OF TRANSCRIPTION FACTORS ASSOCIATED WITH BREAST CANCER.
May 1, 2001... The goal of this (Health Research Inc.) project is to test and develop a new class of drugs, polyamide, which can selectively and effectively inhibit the function of transcription factors whose aberrant regulation of gene expression is...