Life Sciences & Biotechnology Update articles from June 2000

Life Sciences & Biotechnology Update archives from June 2000

TIME OF INJECTION OF INTRATHECAL ANALGESIA ON THE LENGTH OF EARLY AND ADVANCED LABOR.
June 1, 2000... Controversies in obstetric anesthesia include the effect of regional analgesia on the progress and length of labor. This (Air Force Institute of Technology) thesis-study determines the effect of the timing of intrathecal narcotic analgesia on...

ROLE OF RESIDENTIAL SEGREGATION ON LOW BIRTH WEIGHT IN NEW YORK CITY.
June 1, 2000... This (Syracuse University) study attempts to better understand the role of structural and ecological factors on infant health for Black and White women in New York City (excluding Staten Island). It examines the impact of residential...

SUCCESS RATES OF ASSISTED REPRODUCTIVE TECHNOLOGIES.
June 1, 2000... This (National Center for Chronic Disease Prevention and Health Promotion) publication addresses the success rate of assisted reproductive technologies. It is based on the latest available data collected by the Society for Assisted...

SEDATION OF PEDIATRIC PATIENTS DURING MAGNETIC RESONANCE IMAGING (MRI).
June 1, 2000... Patients must remain immobile for magnetic resonance imaging (MRI). The majority of adult patients are able to remain immobile, however, this is very challenging for pediatric patients. Pediatric sedation is necessary to achieve this...

USING THE BIODETECTOR TO ANALYZE BACILLUS GLOBIGII SPORES.
June 1, 2000... This report from Canada (Defense Research Establishment) concerns the analysis of Bacillus globigii spores using the BioDetector. The Canadian Forces have a mandate to be able to operate under the threat of chemical or biological attack. An...

OPTICAL-COHERENCE TOMOGRAPHIC IMAGING FOR BIOMEDICAL APPLICATIONS.
June 1, 2000... This (Massachusetts Institute of Technology) program is developing and supplying optical-coherence tomography (OCT) for biomedical applications. OCT is a new technology for performing in situ real-time imaging of cross-sectional tissue...

PATIENT INFORMATION ON VISION-RESEARCH CLINICAL TRIALS.
June 1, 2000... This (National Eye Institute) document addresses clinical trials of vision-research for patients. It answers and discusses such questions as: What kinds of clinical trials are there? How is a clinical trial conducted? What are the benefits...

EFFECTIVENESS OF PRENATAL INTERVENTIONS ON WOMEN'S AND CHILDREN'S HEALTH.
June 1, 2000... The objectives of this (Harvard School of Public Health) publication are to: (1) synthesize and summarize research on the effectiveness of prenatal interventions in women's and children's health; (2) identify gaps in the literature and...

REVIEW OF A PROGRAM FOR HEMATURIA SELF-TESTING AMONG A COMMUNITY POPULATION POTENTIALLY EXPOSED TO BLADDER CARCINOGENS.
June 1, 2000... This (Michigan Department of Community Health) report addresses a cross-sectional study of self-testing for hematuria conducted in three communities in Michigan (Adrian, Kalamazoo, and Muskegon) where factories are located that manufactured or...

NEW DIRECTIONS FOR CHEMOPREVENTION RESEARCH AT THE NATIONAL CANCER INSTITUTE.
June 1, 2000... This (National Cancer Institute) report addresses new directions for chemoprevention research. Its partial contents are as follows: Chemoprevention Implementation Group; Organization: Division of Cancer Prevention (Exhibit 1: NCI Division of...

PROSTATE CANCER SURVEY MEASURES FOR AFRICAN-AMERICAN URBAN MEN.
June 1, 2000... The purpose of this (Johns Hopkins University) minority-population-focused program is to conduct research involving the excess burden of prostate cancer among African-American men. The excess burden is defined as: greater incidence; later...

IMMUNOBIOLOGICAL ASPECTS OF erbB RECEPTORS IN BREAST CANCER.
June 1, 2000... This (University of Pennsylvania) work studies the general problem of assembly, activation, and disabling the receptor complexes of the erbB family, and its relevance to cancer. It analyzes how mutants of the endodomain of pl85neu affect the...

BREAST CANCER: HER-2 AS A PROGRESSION FACTOR AND THERAPEUTIC TARGET.
June 1, 2000... This (Georgetown University) work analyzes the interaction of estrogen and HER-2 with respect to MCF-7 human breast cancer cell growth. It was previously observed that upon reduction of llER-2 in MCF-7 cells by ribozyme-targeting, estradiol...

MOLECULAR ANALYSIS OF Bcl-xS-INDUCED APOPTOSIS IN BREAST CANCER.
June 1, 2000... This (University of Michigan School of Medicine) report concerns a major genetic event that occurs in the pathogenesis of breast carcinoma involving alterations in the Bcl-2 survival pathway. The effort is aimed at determining the mechanism...

BREAST CANCER RISK FACTORS: RACIAL AND ETHNIC DIFFERENCES.
June 1, 2000... This (Northern California Cancer Center) report concerns data collection for a population-based case-control study of breast cancer conducted in the San Francisco Bay Area that has been on-going since July 1996. The cases include...

BREAST CANCER: PLEIOTROPHIN AS A GROWTH FACTOR AND THERAPEUTIC AGENT.
June 1, 2000... This (Georgetown University) study addresses the mechanisms of regulation of the pleiotrophin (PTN) gene. The work discovers a germ-line retroviral insertion that contributes to the transcriptional regulation of this gene. Phylogenetic...

CYCLIN D1: ANCHORAGE-INDEPENDENT GROWTH AND BREAST CANCER.
June 1, 2000... This (University of Miami) report addresses derangements in the cell-cycle machinery that contribute to uncontrolled cell growth and tumorigenesis. Regulators of GI progression including cyclin D1 and the cyclin-dependent kinase inhibitors p21...

HUMAN BREAST CANCER GENE THERAPY.
June 1, 2000... This (University of Michigan) research conducts a clinical trial of gene therapy for metastatic breast cancer patients. Surgically-removed tumor cells are maintained in short-term culture and then transduced in the laboratory with an...

THE GULF WAR: PSYCHOLOGICAL AND NEUROBIOLOGICAL CONSEQUENCES.
June 1, 2000... Over the past four years, this (Veteran Administration Connecticut Health Care System) study has followed Desert Storm veterans from two Connecticut National Guard units. The study focuses on the evolution of trauma-related symptoms and the...

VALIDATION STUDIES OF ILLNESS AMONG PERSIAN GULF WAR VETERANS.
June 1, 2000... This (University of Iowa) study has recently completed a population-based cross-sectional telephone survey of 4,886 military personnel, to compare the prevalence of self-reported symptoms and illnesses among military personnel either deployed,...

TREATMENT OF HYPERTENSION: COST AND QUALITY.
June 1, 2000... Hypertension is among the most common clinical conditions seen by physicians in the U.S. Treatment of this condition accounts for substantial health care expenditures. This (Agency for Health Care Policy and Research) report generates...

ORAL CONTRACEPTIVES AND BONE HEALTH AMONG FEMALE RUNNERS.
June 1, 2000... Highly trained female athletes may experience loss of menses, low bone mass, and an increased frequency of stress fractures, because of their participation in intense physical activity. Low serum estrogen levels are believed to be a principal...

EMERGENCY SITUATION RESOURCES FOR FOOD SAFETY AND STORAGE.
June 1, 2000... This (National Agricultural Library) publication contains resources and information for the general public, and for individuals who are educating the public, about responses to emergency situations. The majority of the information focuses on...

SKIN BLOOD-FLOW RESPONSE AND FOREARM HYPEREMIA AFTER INGESTION OF NIACIN.
June 1, 2000... This (Army Research Institute of Environmental Medicine) study measures skin blood-flow and core temperatures before and after niacin ingestion in 8 subjects. Each subject is tested on two occasions, in climatic conditions of 30 C and...

EFFICACY OF 1 MG AND 5 MG DOSES OF MELATONIN ON HEAT TOLERANCE.
June 1, 2000... This report from Canada (Defense and Civil Institute of Environmental Medicine) summarizes the findings from two studies examining whether the reported hypothermic effect of melatonin ingestion increases tolerance to the heat stress of people...