Life Sciences & Biotechnology Update articles from April 1999

Life Sciences & Biotechnology Update archives from April 1999

EVALUATION OF THE CDC-FUNDED TRAUMATIC BRAIN INJURY AND SPINAL-CORD INJURY PROGRAMS.
April 1, 1999... This (Susan Toal) report concerns evaluation of CDC- funded programs dealing with traumatic brain injury and spinal cord injury. In 1988, CDC created the Disabilities Prevention Program (DPP), to reduce the incidence and severity of primary...

THE MECHANISMS OF SUPEROXIDE AND NITRIC OXIDE IN TRAUMATIC BRAIN INJURY AND HEMORRHAGIC HYPOTENSION.(University of Texas report)(Technology Information)
April 1, 1999... This (University of Texas) report concerns superoxide and nitric oxide mechanisms in traumatic brain injury (TBI) and hemorrhagic hypotension. TBI reduces cerebral blood flow (CBF) and renders the brain vulnerable to secondary ischemia....

NONINVASIVE MONITORING OF TISSUE REDOX STATUS AND OXYGENATION IN HUMANS.(Technology Information)
April 1, 1999... This report from England (Saint George's Hospital Medical School) investigates a cluster of reliable noninvasive techniques for the tracking of improvements in oxygen delivery, oxygen availability, and oxygen usage, within and in the vicinity...

UNDERSTANDING HOW HIV-INFECTED PATIENTS THINK ABOUT, AND VALUE, THEIR HEALTH.(University of Cincinnati study)(Technology Information)
April 1, 1999... Previous studies of the health values (utilities) of HIV-infected patients have shown that utilities for their current state of health are often high, indicating a strong will to live, and that utilities for current health do not correlate...

MALARIA BIOCHEMISTRY AND CHEMOTHERAPY.(University of Massachusetts study)(Technology Information)
April 1, 1999... Malaria is the world's most ravaging infectious disease; it is rampant throughout much of the tropics and some of the temperate areas of the world. Malaria: threatens a third of the world's population; presently afflicts hundreds of millions...

THERAPY MANUAL FOR COCAINE ADDICTION.(University of Vermont therapy manuals for treatment of cocaine addiction)(Technology Information)
April 1, 1999... These two (University of Vermont) documents are therapy manuals for treating cocaine addiction. The contents of this Manual include: Foreword; Background; Program Overview; Clinical Approach; The Voucher Program; Intake; Early Counseling...

THE VACCINE ADVERSE-EVENT REPORTING SYSTEM.(Government Activity)
April 1, 1999... The National Childhood Vaccine Injury Act of 1986 (NCVIA) requires health care providers and vaccine manufacturers to report to DHHS specific adverse events following the administration of the vaccines outlined in the Act. DHHS established...

RISK FACTORS FOR OSTEOPOROSIS AND ORAL BONE LOSS IN POSTMENOPAUSAL WOMEN.(State University of New York study)
April 1, 1999... This (State University of New York) study determines the relationship between skeletal and oral bone density and identifies factors influencing bone loss. It determines the relationship between osteoporosis and oral bone loss, periodontal...

POSTPARTUM MATERNAL WEIGHT CHANGE.(University of California report)(Technology Information)
April 1, 1999... Maintaining physical readiness to meet demands of combat conditions is of utmost importance for active- duty military personnel. As growing numbers of women of childbearing age enter active-duty military service, the numbers of pregnancies...

NATURE AND OUTCOME OF STRESSORS FOR MILITARY WOMAN.(Research Triangle Institute study)(Technology Information)
April 1, 1999... This (Research Triangle Institute) report summarizes the literature on stressors, and outcomes associated with stressors, focusing particularly on findings on women. It presents the technical objectives, the hypotheses, and the methodology...

PREDICTORS OF BACK INJURIES AMONG MILITARY WOMEN RECRUITS.(University of Alabama report)(Technology Information)
April 1, 1999... Military recruit training is physically demanding, and results in a high rate of musculoskeletal injuries. Identification of back injury risk factors, and the successful development of preventive measures, could significantly decrease:...

STUDY OF THE TRANSPORTER CONCENTRATION OF CARCINOGENS IN BREAST EPITHELIA.(Medical University of South Carolina study)(Technology Information)
April 1, 1999... This (Medical University of South Carolina) report examines the possibility that the membrane transporter, Pgp, could continually or episodically (under the influence of various steroid hormones or environmental factors) transport hydrophobic...

EFFECT OF RADIOTHERAPY ON PRIMARY HUMAN MAMMARY EPITHELIAL CELLS HARBORING A BREAST CANCER SUSCEPTIBILITY GENE.(University of Michigan report)(Technology Information)
April 1, 1999... This (University of Michigan) work determines whether breast cancer predisposition is correlated with enhanced cellular sensitivity to radiotherapy. Mammary epithelial cells from women at high risk for carrying either a BRCA-1 or BRCA-2...

PREVENTING FATIGUE IN WOMEN TREATED FOR BREAST CANCER WITH CHEMOTHERAPY.(University of Rochester report)(Technology Information)
April 1, 1999... This (University of Rochester) report describes a randomized double-blind placebo-controlled clinical trial with 130 consecutive breast cancer patients who are being studied over four successive chemotherapy treatments, to assess if an...

MECHANISMS OF BREAST CANCER-INDUCED OSTEOLYSIS.(Barnes Hospital study)(Technology Information)
April 1, 1999... This (Barnes Hospital) study demonstrates that the expression level of the integrin, alphavbeta3, correlates with organ-specific targeting of human breast tumor cells, such that low integrin-expressing cells preferentially home to bone, while...

EFFECTS OF A COMPREHENSIVE COPING STRATEGY ON THE CLINICAL OUTCOMES IN BREAST CANCER BONE-MARROW TRANSPLANT PATIENTS AND PRIMARY CAREGIVERS.(Johns Hopkins University study)(Technology Information)
April 1, 1999... This 4-year (Johns Hopkins University) study determines the effects of the Comprehensive Coping Strategy Program (CCSP) on clinical outcomes and quality of life in breast cancer patients and their primary caregivers (PCGs). Specifically, it...

SYMPTOMS AND HORMONES IN WOMEN AT HIGH RISK FOR BREAST CANCER.(Tufts University study)(Technology Information)
April 1, 1999... Women at high risk for breast cancer, who are experiencing menopausal symptoms of hot flashes, are being recruited for this (Tufts University) study in Boston and surrounding areas. The study has already recruited 80 out of the 100...

OCULAR MELANOMA COLLABORATIVE STUDY.(Collaborative Ocular Melanoma Study Coordinating Center report)(Technology Information)
April 1, 1999... This (Collaborative Ocular Melanoma Study Coordinating Center) report focuses on the Collaborative Ocular Melanoma Study (COMS), which is a multicenter investigation designed to evaluate therapeutic interventions for patients who have...

ESTIMATING THE CONCENTRATION OF CARBON DIOXIDE (CO2) NEAR AN INFANT'S FACE.(Defense and Civil Institute of Environmental Medicine of Canada report)(Technology Information)
April 1, 1999... This report from Canada (Defense and Civil Institute of Environmental Medicine) investigates the possibility that CO2 build-up may have been a predisposing factor in the death of an infant. The report: presents an account of the circumstances...

RESPONSE OF MUSCLE AND LIVER CARBOHYDRATES TO MOTION AND EXERCISE.(Yale University study)(Technology Information)
April 1, 1999... This (Yale University) study assesses the response of muscle and liver carbohydrates to motion and exercise. The work covers three areas: (1) design of the exercise ergometer and development of a reliable experimental protocol; (2) validation...

STRUCTURE AND FUNCTION OF THE RECOMBINANT HUMAN ESTROGEN RECEPTOR.(University of California report)(Technology Information)
April 1, 1999... This (University of California) report concerns the structure and function of the recombinant human estrogen receptor. Interaction of the estrogen receptor with its ligands is mediated by a C-terminal region of the protein, designated the...

NEUROPHARMACOLOGICAL CHARACTERIZATION OF THE BOTULINUM NEUROTOXIN.(Thomas Jefferson University report)(Technology Information)
April 1, 1999... This (Thomas Jefferson University) report concerns the neuropharmacological characterization of botulinum neurotoxin. The binding of iodinated botulinum toxin to nerve membranes is studied by using rat and mouse preparations. The toxin is...