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Life Sciences & Biotechnology Update articles

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MENTAL HEALTH AND HUMAN SERVICES WORKERS IN MAJOR DISASTERS: A TRAINING MANUAL.
August 1, 2001... The primary purpose of this (Substance Abuse and Mental Health Services Administration) manual is to present an overview of essential information including: how disasters affect children, adults, and older adults; the importance of tailoring the program to fit the community; descriptions of...

INSECTS AS MODEL SYSTEMS FOR NEURONAL DEVELOPMENT AND REPAIR MECHANISMS.
August 1, 2001... An experimental drug, PDMP, has been shown to block metastasis by inhibiting the display of carbohydrates on tumor cell surfaces. Further work with PDMP and related drugs to prevent the spread of cancer now seems justified. This (University of Arizona) work is intended to show that rapidly...

NEUROCHEMICAL, MOLECULAR, AND GENETIC FACTORS OF CHRONIC STRESS AND NEURONAL PATHOLOGY.
August 1, 2001... This (Scripps Research Institute) publication tests the hypothesis that chronic stress produces lasting changes in brain dopamine function, leading to permanent neuronal damage through oxidative mechanisms. Certain subject populations may be uniquely susceptible to this pathological cascade,...

BRAIN MITOCHONDRIA: PRO-APOPTOTIC CHANGES AFTER TOXIN EXPOSURE.
August 1, 2001... Mitochondria normally function to provide sources of energy for vital cellular functions; however, under stressful conditions these organelles may trigger events that lead eventually to cell death. Thus, mitochondria have been implicated as major contributors to neuronal death in a variety...

KAINIC-ACID-INDUCED NEURODEGENERATION: PROTECTIVE MECHANISMS OF NITRONE ANTIOXIDANTS.
August 1, 2001... This (Oklahoma Medical Research Foundation) research focuses on developing nitrone-based antioxidants as antidotes against chemical agents that induce excitatory neurotoxicity. It is proposed to use kainic acid, an analog of the excitatory amino acid glutamate, to induce chronic...

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