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BASIC SCIENCE: DNA Movements in Living Cells.
September 1, 2001... Scientists at the University of Illinois, led by Christopher Bardeen, a UI professor of chemistry, can measure the movement of chromatin within the nucleus of a living cell. They reported on their technique at the 222nd American Chemical...
GENOMICS: Half of Mouse Genome Knocked Out.
September 1, 2001... Lexicon Genetics, Inc. (4000 Research Forest Dr., The Woodlands TX 77381; Tel: 281/364-0100 or 800/578-1972, Fax: 281/364-0155; Website: www.lexgen.com) has altered more than one-half of the genes in the mouse genome for use in human drug...
Mutation Limits HIV Epidemic.
September 1, 2001... Absence of a genetic mutation that protects people from HIV infection could be a major factor responsible for the current AIDS epidemic in sub-Saharan Africa, according to a model developed by University of Michigan (U-M) scientists.
"The...
Longevity Genes on Chromosome Four?
September 1, 2001... By comparing the DNA of siblings who are extremely long-lived, Louis Kunkel and Thomas Perls believe they have found a region on chromosome 4 that may hold an important clue to understanding human longevity. Their results are published in the...
Gene Expression in Calorie-Deprived Mice.
September 1, 2001... A study of 11,000 genes in the livers of mice that compares gene expression in normally aging and calorically restricted mice, by Stephen Spindler, of the University of California, Riverside was published in the latest issue of the Proceedings...
Gene Involved in Memory Discovered.
September 1, 2001... Researchers at the Robert Wood Johnson Medical School have discovered a key memory gene, Rab3A (pronounced rab-3-A). They found the gene necessary in allowing memory neurons in the brain to converse fluently with one another, as measured by...
Metal-Eating Plants Deciphered.
September 1, 2001... Genes thought to allow plants to accumulate large amounts of metal in their tissues have been identified and cloned by a Purdue University scientist David E. Salt, associate professor of plant molecular physiology. His research is published in...
Gene Expression in Prostate Cancer.
September 1, 2001... A study from the University of Michigan Medical School (Ann Arbor, MI), published in the August 23 issue of Nature, offers a first look at the genetic and molecular profile of prostate cancer.
"Our study has important applications in the...
Speciation Genes Stick Together.
September 1, 2001... In a study published in the August 30 edition of the journal Nature, Sara Via, an evolutionary biologist, and insect geneticist David Hawthorne, both from the University of Maryland, College Park, discovered that genes involved in speciation...
Archaea Demonstrates Unique Biochemistry.
September 1, 2001... Robert H. White, of Virginia Tech (Blacksburg, VA) is discovering unique biochemistry in Methanococcus jannaschi, an example of Archeae bacteria. At only 1,800 genes, it is the smallest of the group and the first to have its genome sequenced...
CELL THERAPY: Embryonic Cell Lines Listed.
September 1, 2001... The Bush administration has released the list of embryonic stem cell lines that can be used for federally funded research. Release of the list, however, will not stem the controversy surrounding Bush's decision to limit federal funding.
...
Stem Cells Can Become Blood Cells.
September 1, 2001... Scientists form the University of Wisconsin-Madison have demonstrated that undifferentiated human embryonic stem cells can be directed down a developmental pathway to become white and red blood cells. The work was reported in the Proceedings of...
VACCINES: Uganda Collaborates on AIDS Vaccine.
September 1, 2001... The International AIDS Vaccine Initiative (IAVI) and the Government of the Republic of Uganda have signed a partnership agreement aimed at accelerating the development and testing of preventive AIDS vaccines for Uganda and the world.
...
Reports on AIDS Vaccine Progress.
September 1, 2001... Anthony S. Faucci, director of the National Institute of Allergy and Infectious Diseases (NIAID) (Bethesda, MD) reviewed challenges and recent progress in the search for a vaccine against HIV at the recent AIDS Vaccine 2001 meeting held in...
Bilosomes-Agents for Delivering Vaccines.
September 1, 2001... BTG, plc (10 Fleet Place, Limeburner Lane, London EC4M 7SB, U.K.; Tel: 4490 7575 0000, Fax: +44 (0)20 7575 0010; Website: www. btgplc.com) has acquired Bilosomes, a new oral vaccine delivery vesicle that protects antigens from the digestive...
ANTIBODIES: IgA Platform Under Development.
September 1, 2001... Cangene Corporation (104 Chancellor Matheson Rd., R3T 5Y3, Winnipeg, Manitoba, Canada; Tel: 204/275-4200; Website: www.cangene.com) has begun developing a new antibody-based platform technology, based on the IgA class of antibodies. The...
Antibody Drug for Pseudomonas Infection.
September 1, 2001... InterMune, Inc. (1710 Gilbreth Rd., Burlingame, CA; Tel: 650/409- 2120; Email: ir@intermune.com, Website: www.intermune.com) has accepted a humanized monoclonal antibody targeted against the PcrV protein of the bacterium Pseudomonas aeruginosa....
Ag-Bio: Invader Attacks Plant World.
September 1, 2001... Third Wave AgBio, Inc. (Madison, WI) is leveraging Third Wave Technologies (502 Rosa Rd., Madison, WI 53716-1256; Tel: 608/273- 8933; Website: www.twt.com) Invader technology by using it for the detection of genetic variation in plants and...
Genetics of Miniature Plants.
September 1, 2001... How do organisms maintain their size and shape despite varying environmental conditions? Unlike warm-blooded animals, plants cannot maintain their internal body temperatures during ambient temperature changes. It turns out that plants have...
EC Grant for Meat Quality Awarded.
September 1, 2001... The European Commission recently awarded a project grant to PIC International Group, (2929 Seventh St., Suite 130, Berkeley, CA 94710; Tel: 510/848-8266, Fax: 510/848-0324; Website: www.pic.com), which bills itself as the world's leading swine...
INDUSTRY NEWS: Venture Capital for Michigan.
September 1, 2001... Sloan Ventures, LLC have announced the establishment of the Michigan Life Sciences Corridor (MLSC) Catalyst Fund. The MLSC Catalyst Fund provides seed funding to companies engaged in life sciences research that have a substantial portion of...
Impact of Genomics on Pharma R & D.
September 1, 2001... A panel discussion was held for members of the press on the impact of genomics on pharmaceutical research, at the recent Drug Discovery Technology 2001 conference held in Boston and organized by IBCUSA. The panel members agreed, that despite...
CALENDAR.
September 1, 2001... October 15-16, 2001. Protein Kinases in Drug Discovery and Development, Princeton, NJ, Strategic Research Institute; Tel: 212/967-0095, ext. 243; Email: jliong@srinstitute
October 18-19, 2001. Vaccines of the Future: From Rational Design...