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BASIC SCIENCE: How to Make Mice with Large Brains.
November 1, 2001... Howard Hughes Medical Institute investigator Hong Wu and colleagues at the UCLA School of Medicine (Los Angeles, CA) reported on the regulatory role of the product of the gene PTEN in the November 1, 2001 issue of Science Express, an online...
GENOMICS: High-Density Bone Gene Discovered.
November 1, 2001... Scientists at Genome Therapeutics (200 Boston Ave., Medford, MA 02155; Tel: 781/395-4100, Fax: 781/395-1225) and Creighton University (2500 California Plaza, Omaha, NE 68178; Tel: 402/280- 2700; Website: www.creighton.edu) described the...
DNA Banking Services Offered.
November 1, 2001... Genomics Collaborative, Inc. (GCI, 99 Erie St., Cambridge, MA; Tel: 617/661-2400, 877/GENOMIX, Fax: 617/661-8899; Website: www.genomicscollaborative.com) will provide DNA banking and other services to Cypress Bioscience, Inc. (4350 Executive...
Icy-Fire Disrupts Immune System.
November 1, 2001... Hal M. Hoffman and colleagues report in the November issue of Nature Genetics, that a protein they have named cryopyrin is the likely defect in two periodic fever syndromes: familial cold autoinflammatory syndrome (FCAS), in which affected...
MicroRNAs Are Form of Gene Regulation.
November 1, 2001... Victor Ambros, professor of genetics at Dartmouth College (Hanover, NH, 03755; Tel: 603/646-1110; Website: www.dartmouth.edu) and research associate Rosalind C. Lee have discovered a family of unusually small genes that act in the finely tuned...
Toxicogenomics Consortium Forms.
November 1, 2001... The National Institute of Environmental Health Sciences (NIEHS) has awarded $37 million to five academic organizations that, in association with NIEHS, will form the Toxicogenomics Research Consortium. Each of the organizations will receive $7...
Parkinson's Disease Gene Found.
November 1, 2001... Scientists at deCODE genetics (Lynghals 1, IS-110 Reykjavik, Iceland; Tel: 354/570-1900, Fax: 354/570-1901; Website: www.decode.com) have mapped a gene contributing to late-onset Parkinson's disease, the first known genetic factor for the most...
Puffer Fish Draft Genomic Sequence Completed.
November 1, 2001... A draft sequence of the genome of the gastronomic delicacy, the Japanese puffer fish, Fugu rubripes, was announced at the 13th International Genome Sequencing and Analysis Conference in San Diego, California, on October 26th.
Although...
Framingham Study Adds Third Generation.
November 1, 2001... The world's longest running clinical study, the Framingham Heart Study (FHS)-which gave the world the term "risk factor"-is about to enter a new phase by recruiting its third generation of participants. The Third Generation Study is expected to...
GENE THERAPY: Parkinson's Disease Therapy Patented.
November 1, 2001... U.S. Patent 6,309,634 (the '634 patent) has been issued covering a gene therapy approach for treating Parkinson's disease. The treatment entails using Avigen's (1301 Harbor Bay Pkwy., Alameda, CA 94502; Tel: 510/748-7150, Fax: 510/748-7155;...
Grant Awarded for Bone Regeneration.
November 1, 2001... Regeneration Technologies, Inc. (RTI, 1 Innovation Dr., Alachua, FL 32615; Tel: 386/418-8888 or 386/418-0342) has received a $2 million award from the National Institute of Standards and Technology's (NIST) Advanced Technology Program (ATP) to...
Congestive Heart Failure Patent Issued.
November 1, 2001... U.S. Patent 6,306,830, entitled "Gene Therapy for Congestive Heart Failure" has been issued to the University of California. The patent relates to methods of in vivo gene transfer via nonsurgical administration for the potential treatment of...
CELL THERAPY: Grant Awarded for Engineered Cartilage.
November 1, 2001... Isto Technologies, Inc. (1125 Olivette Executive Pkwy., Suite 110, St. Louis, MO 63132-2320; Tel: 314/995-6049, Fax: 314/995-6025; Website: www.istotech.com) has received a 3-yr. Advanced Technology Program (ATP) award of $2 million from the...
Cross-Talk Between Nerves and Fat.
November 1, 2001... Growing fat cells and nerve cells in the same dish has produced what is believed to be the first demonstration of two-way communication between the cell types, according to Christine Turtzo, an M.D.-Ph.D. candidate at The Johns Hopkins...
Cord Blood Stem Cell Projects Initiated.
November 1, 2001... ThermoGenesis Corp. (3146 Gold Camp Dr., Rancho Cordova, CA 95670; Tel: 916/858-5100, Fax: 916/635-2163) and Kourion Therapeutics GmbH (Bldg. 14.80 MED of Heinrich-Heine, Moorenstrasse 5, Dusseldorf, Germany 40225; Tel: 011 49 211 811 95 45)...
StemSource Opens for Business.
November 1, 2001... StemSource, Inc. (1125 Business Center Circle, Thousand Oaks, CA 91320; Tel: 800/789-6099 or 805/480-3880, Fax: 805/480-3871; Website: www.stemsource.com) has completed its initial funding round, opened new headquarters in Thousand Oaks,...
ANTIBODIES: BLyS Treats Autoimmune Disease.
November 1, 2001... The U.S. Food & Drug Administration has approved an Investigational New Drug application from Human Genome Sciences, Inc. (9410 Key West Ave., Rockville, MD 20850; Tel: 301/309-8504, Fax: 301/309-8512) to begin clinical trials of LymphoStat-B...
Combinatorial Antibody Library Patented.
November 1, 2001... MorphoSys AG (Lena-Christ-Strasse, D-82152 Martinsied, Munich, Germany; Tel: + 49 (0)89 99927 0, Fax: +49 (0)89 89927 222) has been granted a patent covering its Human Combinatorial Antibody Library (HuCAL). The patent (U.S. Patent 6,300,064),...
HORMONES AND CYTOKINES GM-CSF Promotes Arteriogenesis.
November 1, 2001... A human protein widely used to mobilize hematopoietic stem cells for transplants has now shown promise for growing new blood vessels in people with coronary artery disease, according to a study done by Swiss researchers led by Christian Seiler,...
VACCINES: West Nile Virus Vaccine Developed.
November 1, 2001... Yale scientists have successfully immunized mice against West Nile virus, raising the possibility of developing a vaccine for humans against the potentially fatal viral infection. Results of the study were published in the November issue of the...
D.A.M. Vaccine Beats Natural Immunity.
November 1, 2001... A Remedyne Corp. (2219 Bath St., Santa Barbara, CA 93105; Tel: 805/687-0251, Fax: 805/687-0402; Website: www.remedyne.com) vaccine produces a cross-protective immunity against multiple Salmonella strains in mice, and unlike other Salmonella...
AG-BIO: Arabidopsis Genome Microarray on the Way.
November 1, 2001... Agilent Technologies, Inc. (3000 Hanover St., Palo Alto, CA 94304; Tel: 650/857-1501, Fax: 650/857-7299; Website: www.agilent.com) and Paradigm Genetics (108 Alexander Dr., Research Triangle Park, NC 27709-4528; Tel: 919/425-3000, Fax:...
Substitute Cellulose from Cyanobacteria.
November 1, 2001... Cellulose from cyanobacteria may be a promising new resource for the industrial production of the substance and could eventually eliminate the need to harvest trees for wood or pulp, according to researchers at the University of Texas at Austin...
INDUSTRY NEWS: DeCode Genetics to Patent 350 Genes.
November 1, 2001... deCODE Genetics (Lynghals 1, IS-110 Reykjavik, Iceland; Tel: 354/570-1900, Fax: 354/570-1901; Website: www.decode.com) scientists using the company's data-mining products have to date discovered 350 genes in key drug target classes. These...
Synaptic Files Against Euroscreen S.A.
November 1, 2001... Synaptic Pharmaceutical Corp. (215 College Rd., Paramus, NJ 07652; Tel: 201/261-1331, Fax: 201/261-0623) has filed an amended suit in the United States District Court for the District of New Jersey against Euroscreen, S.A. (Route de Lennik 802,...
Hyseq Forms Sequencing Unit.
November 1, 2001... Hyseq (670 Almanor Ave., Sunnyvale, CA 94086; Tel: 408/524-8100; Website: www.hyseq.com) will create a new majority-owned subsidiary, known as Callida Genomics, Inc., to focus on the development and commercialization of Hyseq's sequencing-by-...
CALENDAR.
November 1, 2001... November 19-21, 2001. Biomics 2001, Frankfurt, Germany, IBC; Tel: +44 193-289-3888; Website: www.ibc-biomics.com
December 3-4, 2001. Metabolic Profiling: Pathways to Discovery, Chapel Hill, NC, Cambridge Healthtech Institute; Tel: 617/630-...