Applied Genetics News articles from January 2000

Applied Genetics News archives from January 2000

BASIC RESEARCH: The Smallest Moving Machine.(kinesin motors, applications against cancer)(Brief Article)
January 1, 2000... "The kinesin motors responsible for this transport are the world's smallest moving machines, even the smallest in the protein world," says Howard Hughes investigator Ronald Vale of the University of California, San Francisco. "So, besides...

GENOMICS: Changing White Hairs to Black.(oligonucleotides to change mouse hair color)(Brief Article)
January 1, 2000... No, it's not a new kind of hair dye. Researchers at Jefferson Medical College have used a gene repair technique to genetically change white albino mice hairs to black by correcting a point mutation in the tyrosinase gene. The genetic changes...

Type-2 Diabetes Gene Discovered.(gene associated with insulin resistance)(Brief Article)
January 1, 2000... Incyte Pharmaceuticals, Inc. (3174 Porter Dr., Palo Alto, CA 94304; Tel: 650/855-0555, Fax: 650/855-0572; Website: incyte.com), in collaboration with researchers at the University of Cambridge (U.K.), have identified a gene that is responsible...

Universal Cloning Technology Patented.(Life Technologies, Inc. releases Gateway Cloning Technology)(Brief Article)
January 1, 2000... Life Technologies, Inc. (9800 Medical Center Dr., Rockville, MD, 20850; Tel: 301/610-8000, Fax: 301/610-8020; Website: lifetech.com) has released its Gateway Cloning Technology in response to the growing need for faster, more efficient ways to...

Gene Expressed in Lung Cancer.(study of EGFL6)(Brief Article)
January 1, 2000... Hyseq, Inc. (670 Almanor Ave., Sunnyvale, CA 94086; Tel: 408/524-8100; Website: hyseq.com) has published a study of EGFL6, an anti-tumor drug target candidate, in Genomics [62, 303-307]. Results of the study indicate that the gene is...

ANTIBODIES: Biologics License Filed for Campath.(monoclonal antibody for treatment of b-cell chronic lymphocytic leukemia)(Brief Article)
January 1, 2000... ILEX Oncology, Inc. (11550 Hwy. 10 W., Suite 100, San Antonio, TX 78230; Tel: 210/949-8200, Fax: 210/949-8210; Website: ilexoncology.com) and Millennium Pharmaceuticals, Inc. (640 Memorial Dr., Cambridge, MA 02139; Tel: 617/679-7000, Fax:...

Maryland Wins Grant for Heart Research.(Myocarditis research)(Brief Article)
January 1, 2000... CEL-SCI Corp. (8229 Boone Blvd., Suite 802, Vienna, VA 22182; Tel: 703/506-9460, Fax: 703/506-9471) and Noel Rose, professor of pathology and medicine at the Department of Pathology, The Johns Hopkins Medical Institutions, (Baltimore, MD)....

Macrophage Monoclonal Fights Inflammation.(MDX-44 immunotoxin developed by Medarex, Inc.)(Brief Article)
January 1, 2000... Medarex, Inc. (1545 Rte. 22 E., Annandale, NJ 08801-0953; Tel: 908/713-6001, Fax: 908/713-6002; Website: medarex.com) has published result of a new study concerning its MDX-44 drug candidate in the January 2000 issue of Nature Biotechnology....

Searle and Cambridge Combine Efforts.(develop monoclonal antibody-based therapeutic drugs)(Brief Article)
January 1, 2000... Cambridge Antibody Technology (CAT, The Science Park, Melbourne, England, Cambridgeshire, SG8 6JJ U.K.; Tel: 1763-363-223, Fax: 1763-263-413; Website: catplc.co.uk) has entered into a multidisciplinary strategic alliance with Searle, the...

Synthetic Antibody Substitutes Produced.(research of peptides)(Brief Article)
January 1, 2000... Researchers from UT Southwestern Medical Center (Dallas, TX) have discovered a method that may lead to efficient and inexpensive production of synthetic antibody substitutes for use in medical diagnostics, biotechnology, and biomedical...

BIOMANUFACTURING: High Yields of a Fusion Protein.(NeoRx Corp. )(Brief Article)
January 1, 2000... Researchers at NeoRx Corp. (410 W. Harrison St., Seattle, WA 98119; Tel: 206/281-7001, Fax: 206/298-9442) have successfully produced in bacteria a fusion protein intended for use in the company's Pretarget Lymphoma product. The fusion protein...

Radiolabeling Patent Granted.(Brief Article)
January 1, 2000... Immunomedics, Inc. (300 American Rd., Morris Plains, NJ 07950; Tel: 973/605- 8200, Fax: 973/605-8282; Website: immunomedics.com) has received U.S. Patent 6,010,680 for a method of radiolabeling proteins by use of a new radiometal- binding...

CELL THERAPY: Mixed Chimerism Patent Awarded.(Brief Article)
January 1, 2000... U.S. Patent 6006752, entitled "Mixed Chimerism and Tolerance," covering BioTransplant's (Bldg. 75, Third Ave., Charlestown Navy Yard, Charlestown, MA 02120; Tel: 617/241-5200, Fax: 617/241-8780) approach to transplantation and blood cell...

Grant Awarded to Cell Based Delivery.(Brief Article)
January 1, 2000... Cell Based Delivery, Inc. (275 Westminster St., #400, Providence, RI 02903-3434; Tel: 401/453-3540) was awarded a $2 million, three-year grant from the Advanced Technology Program (ATP) of the Commerce Department's National Institute of...

Patent for Engraftable Neural Stem Cells.(Brief Article)
January 1, 2000... The Children's Medical Center (Boston, MA) and physician Evan Y. Snyder, M.D., phD, have received U.S. Patent 5,958,767 for a process in which human neuronal stem cells are isolated and maintained as a stable cell line in vitro. Layton...

Ortec, MIT in Tissue- Engineering Pact.(Ortec International Inc.)(Massachusetts Institute of Technology)(Brief Article)
January 1, 2000... Ortec International, Inc. (3690 Broadway, New York, NY; Tel: 212/740-6999, Fax: 212/740-6963) has entered into a research collaboration with the Massachusetts Institute of Technology (MIT) and Tufts University that will focus on the use of...

HORMONES AND CYTOKINES: Angiopoietins Induce Blood Vessel Repair.(Brief Article)
January 1, 2000... Scientists at Regeneron Pharmaceuticals, Inc. (777 Old Saw Mill River Rd., Tarrytown, NY 10591; Tel: 914/347-7000, Fax: 914/347-2113), in collaboration with colleagues at the University of California at San Francisco, report that Regeneron's...

Relaxin May Treat Infertility.(Brief Article)
January 1, 2000... Connetics Corp. (3400 W. Bayshore Rd., Palo Alto, CA 94303; Tel: 650/843-2800, Fax: 850/843-2899; Website: connetics.com) has initiated two clinical trials to evaluate the role of recombinant human relaxin in improving embryo implantation to...

Hepatitis-B Vaccine Prevents Liver Cancer.(Brief Article)
January 1, 2000... The U.S. Food and Drug Administration (FDA) has recognized the Centers for Disease Control and Prevention's (CDC) description of hepatitis-B vaccines as preventing hepatitis-B infections that can lead to primary liver cancer. SmithKline...

Nicotine Vaccine Appears Effective.(Nabi-NicVAX )(Brief Article)
January 1, 2000... Nabi (5800 Park of Commerce Blvd. N.W., Boca Raton, FL 33487; Tel: 561/989-5800, Fax: 561/989-5801) and collaborators from Minneapolis Medical Research Foundation and the University of Houston (Clear Lake, TX) have published results from...

Cultivation of a Tick-Borne Pathogen.(Brief Article)
January 1, 2000... Aquila Biopharmaceuticals, Inc. (175 Crossing Blvd., Framingham, MA 01702; Tel: 508/628-0100, Fax: 508/791-0224) has been issued a U.S. Patent 5,976,860 covering isolation of the tick-borne pathogen responsible for causing the disease human...

ENZYMES: Enzyme Is Target for Cancer Drug.(Brief Article)
January 1, 2000... New York University (NYU) School of Medicine and Pharmacia & Upjohn (P&U, 95 Corporate Dr., Bridgewater, NJ 08807; Tel: 908/768-5501, Fax: 908/306-4433) have entered into a multi-year research and license agreement to collaborate on the...

INDUSTRY NEWS: Burrill Sums Up the Fourth Quarter.(Brief Article)
January 1, 2000... According to Burrill & Co. (120 Montgomery St., San Francisco, CA; Tel: 415/399- 4360), the fourth quarter was a good one for raising money. The biotechnology industry raised $7.24 billion, a 72% increase from the third quarter of the same...

Immortality Is at Hand.(Brief Article)
January 1, 2000... By the close of 2001, humankind will realize numerous scientific and medical phenomena that will revolutionize the delivery of health care. As a result, the quantity, as well as quality, of the human life span will forever be changed for the...

Technology Tax Transfer Begins in New Jersey.(Brief Article)
January 1, 2000... The first transaction associated with the new Technology Tax Benefit Transfer Program of New Jersey took place on December 22, 1999, when PSE&G purchased the approved tax benefits of 10 New Jersey-based biotechnology companies. These funds are...

Osteoporosis Genomics Alliance Forged.(Brief Article)
January 1, 2000... Genome Therapeutics Corp. (100 Beaver St., Waltham, MA 02154; Tel: 781/398-2300, Fax: 781/398-9535) has initiated a genomics-based research collaboration to develop novel therapeutics for the prevention and treatment of osteoporosis with...

Taisho Licenses Investigational Drugs.(Brief Article)(Statistical Data Included)
January 1, 2000... Taisho Pharmaceuticals Co. Ltd. (3-24-1 Takada, Toshima-ku, Tokyo, Japan; Tel: 03-3985-1111) has bought into a couple of American drugs at the investigational stage. Neurocrine Biosciences, Inc. (3050 Science Park Rd., San Diego, CA 92121;...

AG-BIOTECH: Test Kits for GM Corn on the Way.(Brief Article)
January 1, 2000... Strategic Diagnostics Inc. (SDI, 111 Pencader Dr., Newark, DE 19702-3322; Tel: 302/456-67899, Tel: 800/242-7472, Fax: 302/458-06770; Website: sdix.com) has announced two Bt Cry1A(b) corn test kits are in the final stages of customer...

Zeneca, Cambridge to Collaborate.(Brief Article)
January 1, 2000... Cambridge Discovery Chemistry, a wholly-owned subsidiary of Oxford Molecular Group plc (The Medawar Centre, Oxford Science Park, Oxford OX4 4GA, U.K.; Tel: +44 1865 784600, Fax: +44 1865 784601), and Zeneca Agrochemicals, the crop protection...

Hyseq and Cyanamid Forge Gene Agreement.(Brief Article)
January 1, 2000... American Cyanamid Co., a subsidiary of American Home Products Corp. (Five Giralda Farms, Madison, NJ 07940; Tel: 973/660-5000, Fax: 973/660-5771; Website: ahp.com), and Hyseq, Inc. (670 Almanor Ave., Sunnyvale, CA 94086; Tel: 408/524- 8100;...

CALENDAR.
January 1, 2000... January 26-30, 2000, Transcription Factor Pathogenesis of Cancer at the Millennium, Dana Point, CA. Contact: American Association for Cancer Research; Tel: 215/440-9300, Fax: 215/351-9165. February 7-8, 2000, Proteomics, London, U.K....