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GENOMICS: Phage Genes Make Bad Bug Worse.
August 1, 2002... Group A "Streptococcus" (GAS) bacteria have acquired virulence factors from bacteriophage, according to Stephen Beres and James Musser of Rocky Mountain National Laboratories (903 South 4th St., Hamilton, MT 59840; Tel: 406/363-9255, Fax: 406/363-9371). Their work, in collaboration with other...

Macular Degeneration Caused by Mutation.
August 1, 2002... How can a single gene cause two very different eye diseases, each affecting a different segment of vision? Research scientist Radha Ayyagari from the University of Michigan W.K. Kellogg Eye Center (1000 Wall St., Ann Arbor, MI; Tel: 734/763-1415; Website: www.Kellogg.umich.edu) has found...

Enzyme Defective in Bleeding Abnormality.
August 1, 2002... Researchers the University of California, San Diego (UCSD) School of Medicine (9500 Gilman Dr., La Jolla, CA 92093; Tel: 858/534- 2230; Website: www.ucsd.edu) found that mutations in an enzyme, sialyltransferase ST3Gal-IV, greatly reduced levels of von Willebrand factor (VWF) in mice, by a...

Defective Gene Causes Bone Defects.
August 1, 2002... Mice lacking a protein called SHIP (Src homology 2-containing inositol-5-phosphatase) have twice as many cells that break down bone as normal mice, according to a study led by F. Patrick Ross at the Washington University School of Medicine (660 Euclid Ave., No. 8057, St. Louis, MO; Tel:...

Malaria Is an Ancient Parasite.
August 1, 2002... From genetic data, researchers at the National Institutes of Health (NIH, 9000 Rockville Pike, Bethesda, MD 20892; Tel: 301/496-4000; Website: www.nih.gov) have concluded that the parasite is genetically more diverse and much older-at least 100,000 yr old-than previously thought. In a...

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