Internal Medicine News articles from January 2008

Internal Medicine News archives from January 2008

FDA gets flak for contrast warning.(News)(Food and Drug Administration)
January 1, 2008... Black box restrictions imposed by the Food and Drug Administration on the use of ultrasound contrast agents have caused consternation among cardiologists and radiologists who fear that the agency's decision will have a chilling effect upon the...

Top 10 reasons for internist visits in 2007.(VITAL SIGNS)(Table)(Brief article)
January 1, 2008... Top 10 Reasons for Internist Visits in 2007 Hypertension* 15.9% Uncomplicated diabetes 6.9% Hyperlipidemia*[dagger] 6.6% Routine medical exam 2.5% Hypercholesterolemia 2.4%...

Low-carb diets are okay for diabetic patients, ADA says: practice guidelines updated for 2008.(News)(American Diabetes Association)
January 1, 2008... New guidance from the American Diabetes Association gives a green light to the use of low-carbohydrate diets as a weight-control measure for patients with diabetes. As part of the ADA's annual update of its clinical practice...

Physicians get a 6-month reprieve from 10% pay cut.(News)
January 1, 2008... In what has become a year-end tradition, last-minute congressional action has staved off deep cuts to the Medicare physician fee schedule. The 2007 version means that physicians won't feel the pinch of a 10.1% pay cut under Medicare;...

Inpatient mortality from heart attack and heart failure declining.(DATA WATCH)(Table)(Brief article)
January 1, 2008... Inpatient Mortality From Heart Attack and Heart Failure Declining (per 1,000 admissions) Acute myocardial infarction Heart failure 1994 125 67 1995 1996 1997 112 57...

Timely trends in 2008 and beyond.(THE EFFECTIVE PHYSICIAN)
January 1, 2008... Trends that we've seen in the first 7 years of this century will continue to shape medical practice as we head into 2008. Here are some key developments to keep an eye on as the decade marches on: * Health information technology (HIT)....

CT screening for which patients?(Letter to the editor)
January 1, 2008... Without belaboring the controversy, I would suggest that the problem with CT screening for lung cancer is with the patient study mix ("CT Not Advised for Lung Cancer Screening," Oct. 15, 2007, p. 1). In our area of upper-middle-class golf...

Easier formula, similar results.(Letter to the editor)
January 1, 2008... For years, I have been taking the hemoglobin [A.sub.1c], subtracting 2, then multiplying this number by 30 to get my estimated blood glucose level ("Equation Ties Hb[A.sub.1c] to Average Blood Glucose," Nov. 1, 2007, p. 25). So for an...

CPT: current procedural tyranny.(Letter to the editor)
January 1, 2008... Am I the only physician who is stunned by the ready acceptance of coding by a once-proud profession? You may be the best MD in the U.S.A. and save lives daily, but if you don't enter the proper code number for your work, you don't get a...

Correction.(Correction notice)
January 1, 2008... In "From Magic to Racing, the Hobbies of Physicians" (The Rest of Your Life, Nov. 15, 2007, p. 35), photo credit for the two images should have been given to Sonja Rothstein.

Pain relievers.(Opinion)(Cartoon)
January 1, 2008... "I'm afraid the tests indicate that what happened in Vegas didn't stay in Vegas."

In fight against MRSA, panic is unwarranted.(methicillin-resistant Staphylococcus aureus)(Editorial)
January 1, 2008... Methicillin-resistant Staphylococcus aureus has become the disease of the moment, with alarming headlines almost daily about the "killer" bacterium. While of course MRSA is a real concern, we physicians can help by reassuring people that we...

'Behind-the-counter' prescribing problematic.(Editorial)
January 1, 2008... Americans are desperate for ways to reduce the costs of health care and improve access to care. At the same time, physicians are frustrated with the status quo. After a 30-year campaign by the media to disparage physicians with negative stories...

MRI spots lung damage from secondhand smoke.(Pulmonary Medicine)
January 1, 2008... CHICAGO -- A novel magnetic resonance imaging technique may have provided the proverbial smoking gun in the secondhand smoking debate. Using helium-3 diffusion MRI, researchers at the University of Virginia in Charlottesville and the...

Carbon monoxide test can be used to identify smokers.(Pulmonary Medicine)
January 1, 2008... CHICAGO -- Dr. Sridhar P. Reddy may have found a way to get around the nearly one-half of patients who lie about their smoking status: pulse CO-oximetry. Pulse CO-oximeters have been used in emergency departments and fire stations to...

Hypomagnesemia may predict acute COPD exacerbations.(Pulmonary Medicine)(chronic obstructive pulmonary disease)
January 1, 2008... CHICAGO -- Serum magnesium is an independent predictor of frequent readmissions for acute exacerbation of chronic obstructive pulmonary disease, Dr. Surya Prakash Bhatt and colleagues reported in a poster at the annual meeting of the American...

Preventable hospitalizations for respiratory conditions.(DATA WATCH)(Table)(Brief article)
January 1, 2008... Preventable Hospitalizations for Respiratory Conditions (number of admissions per 100,000 population) Asthma Chronic obstructive pulmonary disease Bacterial pneumonia 1997 124.5 266.8 ...

OA guidelines take evidence-driven approach.(Rheumatology)(osteoarthritis)
January 1, 2008... FORT LAUDERDALE, FLA. -- New guidelines on the management of hip and knee osteoarthritis aim to provide a consensus about which modalities have been shown to be effective, according to presentations at the World Congress on Osteoarthritis. ...

Joint replacement booklet.(Rheumatology)(Joint Replacement Surgery and You)(Brief article)
January 1, 2008... A 16-page booklet, "Joint Replacement Surgery and You," describes the procedure to the patient or lay reader in simple terms. It is available free of charge from the National Institute of Arthritis and Musculoskeletal and Skin Diseases....

Topical diclofenac significantly eased OA pain.(Rheumatology)(osteoarthritis)
January 1, 2008... BOSTON -- Topical diclofenac sodium gel was associated with statistically significant, clinically meaningful improvements in hand osteoarthritis symptoms in a multicenter, double-blind trial, according to a report at the annual meeting of the...

Single Botox injection reduces osteoarthritis shoulder pain.(Rheumatology)
January 1, 2008... BOSTON -- A single botulinum toxin type A injection can decrease joint pain and improve function in patients with refractory shoulder osteoarthritis, Dr. Jasvinder Singh reported at the annual meeting of the American College of Rheumatology....

Inpatient mortality from hip replacement declining.(DATA WATCH)
January 1, 2008... Inpatient Mortality From Hip Replacement Declining (per 1,000 admissions) Source: Healthcare Cost and Utilization Project ELSEVIER GLOBAL MEDICAL NEWS

Stop ESAs in nonresponders after 6-8 weeks.(Hematology)(erythropoiesis-stimulating agents)
January 1, 2008... An updated clinical practice guideline from the American Society of Hematology and American Society of Clinical Oncology on the use of erythropoiesis-stimulating agents declares epoetin alfa and darbepoetin alfa equally safe and effective. ...

Rivaroxaban beats enoxaparin for averting thromboembolism.(Hematology)
January 1, 2008... ATLANTA -- Rivaroxaban, an investigational oral anticoagulant, is significantly more effective than subcutaneous enoxaparin--the current standard of care--in warding off deep vein thrombosis and pulmonary embolism in patients who have undergone...

Human thrombin approved for intraoperative bleeding.(Hematology)
January 1, 2008... The Food and Drug Administration has approved a thrombin product derived from human plasma to help control bleeding during surgery. The product, which will be marketed as Evithrom, is the first human thrombin approved since 1954 and is the...

Leukemia Tx may be guided by genomic profile.(Hematology)
January 1, 2008... NEW YORK -- When it comes to predicting the behavior of a cancer or its likely response to treatment, epigenomic profiling may be as important as genotyping, perhaps even more so, Dr. Ari Melnick said at the 25th annual Chemotherapy Foundation...

Novel melatonergic antidepressant piques interest.(Psychiatry)
January 1, 2008... VIENNA -- "Agomelatine" was the word on everyone's lips at the annual congress of the European College of Neuropsycho-pharmacology. The buzz surrounding the first melatonergic antidepressant rose in reaction to the presentation of...

Getting the NAC of a novel schizophrenia therapy.(Psychiatry)(N-acetylcysteine)
January 1, 2008... VIENNA -- N-acetylcysteine, an inexpensive supplement widely available over the counter in health food stores, proved safe and effective as adjunctive therapy for chronic schizophrenia in a 6-month, double-blind, placebo-controlled trial, Dr....

Haloperidol may raise risk of heart arrhythmia.(Psychiatry)(Brief article)
January 1, 2008... Patients taking the antipsychotic drug haloperidol may be at increased risk for heart rhythm abnormalities, according to a Food and Drug Administration alert. Revised labeling on the drug, marketed as Haldol, Haldol decanoate, and Haldol...

Postmarket reports spur new modafinil warnings.(Psychiatry)
January 1, 2008... Warnings about serious rashes--including Stevens-Johnson syndrome and hypersensitivity reactions--as well as psychiatric symptoms have been added to the label of modafinil, according to a MedWatch notice issued by the Food and Drug...

Updated guidelines allow cautious use of TZDs.(Endocrinology)(thiazolidinediones)
January 1, 2008... In light of new information regarding thiazolidinediones, the American Diabetes Association and the European Association for the Study of Diabetes have updated their previous diabetes treatment guidelines to urge "greater caution" in the use of...

Ethnicity affects triglycerides' predictive value.(Endocrinology)
January 1, 2008... BOSTON -- When using triglycerides to identify insulin resistance, patient ethnicity must be taken into account. An assessment of the relationship between insulin resistance and triglycerides in nearly 6,000 individuals representing four...

Oral 'speed bump': eat slowly, lose weight.(Endocrinology)
January 1, 2008... NEW ORLEANS -- An oral device that fits in the mouth much like a retainer could help overweight individuals eat more slowly and, in the process, eat less and lose weight, according to a poster presented at the annual meeting of NAASO, the...

Narcotic bowel syndrome requires withdrawal.(Gastroenterology)
January 1, 2008... SALT LAKE CITY -- Narcotic bowel syndrome is a problem that physicians have been sweeping under the rug, and it may be growing in frequency, Dr. Douglas A. Drossman said at the annual meeting of the North American Society for Pediatric...

Number of adenomas predicts colonic recurrence.(Gastroenterology)(Brief article)
January 1, 2008... PHILADELPHIA -- A finding of three or more adenomas on colonoscopy was the strongest predictor of classification of a patient as being at high risk for recurrent adenomas in a review of 800 patients with colonic adenomas identified at their...

Gastric bypass trumps band for weight loss.(Gastroenterology)
January 1, 2008... NEW ORLEANS -- Gastric bypass surgery resulted in more rapid and greater weight loss over a 2-year period than did gastric band surgery, according to a retrospective analysis of both procedures presented at the annual meeting of NAASO, the...

Invasive GAS contacts may not need prophylaxis.(Infectious Diseases)(group A streptococcal )
January 1, 2008... CHICAGO -- Offering prophylaxis to all household contacts of patients with invasive group A streptococcal disease may not be cost effective, according to findings from an epidemiologic study presented at the Interscience Conference on...

Adenovirus 14 caused outbreak of severe CAP.(Infectious Diseases)(community acquired pneumonia)
January 1, 2008... SAN DIEGO -- During the winter of 2006 and the spring of 2007, adenovirus 14 caused a community outbreak of respiratory disease in Oregon, with a fatality rate of 19%, Dr. Paul Lewis reported at the annual meeting of the Infectious Diseases...

Assessment tool offers insight into pneumonia severity.(Infectious Diseases)
January 1, 2008... CHICAGO -- A simple severity-assessment tool for community-acquired pneumonia accurately identified patients needing intensive respiratory or inotropic support in a 7,464-patient, multicenter validation study. SMART-COP was developed as...

Pneumonia patients admitted late to ICU have higher mortality.(Infectious Diseases)(Intensive care units)(Brief article)
January 1, 2008... SAN FRANCISCO -- Patients with community-acquired pneumonia who were admitted to the intensive care unit 2 or more days after diagnosis were more than twice as likely to die within 30 days as were those who were admitted in 24 hours or less,...

Inpatient mortality from pneumonia declining.(DATA WATCH)
January 1, 2008... Inpatient Mortality from Pneumonia Declining (per 1,000 admissions) Source: Healthcare Cost and Utilization Project ELSEVIER GLOBAL MEDICAL NEWS

'Empty calories' increase risk for heart disease.(Cardiovascular Medicine)
January 1, 2008... Women with a so-called empty calorie diet--high in sweetened beverages, red meat, and desserts--had significantly elevated intima-media thickness, compared with women who followed other dietary patterns, including diets high in fat. The...

Epicardial fat may signal increased cardiovascular risk.(Cardiovascular Medicine)
January 1, 2008... NEW ORLEANS -- The fat that surrounds the heart is associated with cardiac abnormalities, including low stroke volume and cardiac output, that are independent of body mass index, a study has found. The finding casts doubt on the widespread...

NCQA [beta]-blocker measure to focus on outpatient use.(Cardiovascular Medicine)(National Committee for Quality Assurance )(Report)
January 1, 2008... WASHINGTON -- The National Committee for Quality Assurance in 2008 will begin reporting in earnest on how many myocardial infarction patients are receiving [beta]-blockers 6 months after hospital discharge, as recommended by the American Heart...

DASH diet shown to lower risk of heart disease and stroke.(Cardiovascular Medicine)
January 1, 2008... Women who followed the Dietary Approaches to Stop Hypertension diet had significant risk reductions of coronary heart disease and stroke, results from a cohort of participants in the ongoing Nurses Health Study showed. Previous studies...

Polyvascular disease boosts risk of CV events.(Cardiovascular Medicine)(cardiovascular)
January 1, 2008... ORLANDO -- Polyvascular disease--symptomatic atherosclerotic disease in more than one arterial bed--was a significant risk factor for new cardiovascular events in a review of nearly 100,000 patients with acute coronary syndrome. "Although...

Hypertension algorithm boosts control rate.(Cardiovascular Medicine)
January 1, 2008... ORLANDO -- A simple hypertension-treatment algorithm was more effective than was guideline-led practice for controlling blood pressure in a controlled study involving 45 family practices in southern Ontario. The cornerstone of the algorithm...

Expand subclinical CVD testing to close the detection gap.(Cardiovascular Medicine)(Cardiovascular diseases)
January 1, 2008... SAN DIEGO -- Consider expanding subclinical cardiovascular disease testing to include asymptomatic high-risk patient populations, Leslee J. Shaw, Ph.D., advised attendees at the annual meeting of the American Society of Nuclear Cardiology. ...

McCain opposes mandating health insurance coverage.(Practice Trends)
January 1, 2008... For Sen. John McCain (R-Ariz.), having health insurance is desirable but not mandatory. "I don't think there should be a mandate for every American to have health insurance," the Republican presidential hopeful said at a forum on health...

ED visits by elderly increase.(POLICY & PRACTICE)(Elderly)(Survey)(Brief article)
January 1, 2008... The number of emergency department visits among elderly persons could almost double from 6 million in 2003 to almost 12 million by 2013, according to an analysis using National Hospital Ambulatory Medical Care Survey data from 1993 to 2003. The...

Center takes on nursing shortage.(POLICY & PRACTICE)(Brief article)
January 1, 2008... A new think tank will address the burgeoning nursing shortage and its impact on patient care. The Center to Champion Nursing in America will focus on increasing funding for nursing education, expanding nurse representation on hospital boards,...

DEA accused of electronic stalling.(POLICY & PRACTICE)(Drug Enforcement Administration)(Brief article)
January 1, 2008... The Drug Enforcement Administration, which prosecutes crimes involving illicit use of controlled substances, has been criticized for stalling implementation of a national electronic prescribing system for controlled substances. At a Senate...

FDA can't fulfill mission.(POLICY & PRACTICE)(Food and Drug Administration)(Brief article)
January 1, 2008... Three members of the Food and Drug Administration's Science Board issued a damning report on the state of the agency, saying that it "suffers from serious scientific deficiencies and is not positioned to meet current or emerging regulatory...

Access reduced by cost.(POLICY & PRACTICE)(Brief article)
January 1, 2008... Forty million Americans can't get access to needed health care, and 20% said the main reason was because they could not afford the services, according to a December report by the Centers for Disease Control and Prevention. "Health, United...

Agency's approval plan flawed.(POLICY & PRACTICE)(Brief article)
January 1, 2008... The Food and Drug Administration is considering new guidance that would allow drug companies to use journal articles to promote "potentially dangerous uses" of drugs and medical devices without prior FDA review and approval, according to a top...

Safety net being stretched to the breaking point.(Practice Trends)
January 1, 2008... WASHINGTON -- Community health centers, public hospitals, and other safety net providers are seeing a steadily growing number of low-income patients, while specialty care for these patients is becoming scarce, according to the results of a...

Should alcohol-dependent patients be reported?(Practice Trends)
January 1, 2008... MIAMI BEACH -- Only six states have mandatory reporting laws, so most physicians can be in a quandary when a patient is alcohol dependent and works where impairment could threaten public safety, according to a poster presented at the annual...

Helping people on the fringes in Ethiopia.(WORLD WIDE MED)(Interview)
January 1, 2008... DR. RICK HODES, a Johns Hopkins-trained internist practicing in Addis Ababa, Ethiopia, crunches numbers to see how he can raise funds for his endless stream of patients who need spine and heart surgeries performed in the United States and other...

Indications' case of the month.(INDICATIONS)(Brief article)
January 1, 2008... A new weight-loss fad is gaining traction following the publication in the New England Journal of Medicine of a unique case of severe trichophagia. For those of you who are rusty on your Trivial Pursuit-worthy medical terminology, that means...

Tuition well spent.(INDICATIONS)(Brief article)
January 1, 2008... Rates of alcohol consumption by University of Texas, Austin, college students on days of football games rivaled levels seen on such "traditional" drinking days as New Year's Eve and Halloween. "Many college students view campus sporting events...

Dancing, not falling.(INDICATIONS)(Brief article)
January 1, 2008... A series of 20 hour-long dance classes led to a greater improvement in Parkinson's disease patients' balance than did regular exercise classes, according to a study in the American Journal of Dance Therapy. The study recruited 9 PD patients and...

Surgeon General hates fun, children.(INDICATIONS)(Brief article)
January 1, 2008... Now that the holidays are over and the presents already have been delivered, we think it's safe to say--Santa could stand to lose a few pounds. Or anyway, that's what U.S. Surgeon General Dr. Steven K. Galson told the Boston Herald. "It is...

Less recurrence with anastrozole.(News)
January 15, 2008... SAN ANTONIO -- The efficacy of the aromatase inhibitor anastrozole for prevention of breast cancer recurrence persists for years after treatment completion--but the side effects do not, according to the 100-month follow-up analysis of the...

Adults who did not receive needed health care because they could not afford it.(VITAL SIGNS)(Statistical table)(Brief article)
January 15, 2008... Adults Who Did Not Receive Needed Health Care Because They Could Not Afford It Age (years) 18-44 8.1% 45-64 7.7% [greater than or equal to]65 2.5% Note: Based on 2005 data from...

ESAs may boost leukemia risk in myelofibrosis: retrospective analysis shows association.(News)(erythropoietic-stimulating agents)
January 15, 2008... ATLANTA -- Physicians at the Mayo Clinic in Rochester, Minn., stopped giving erythropoietic-stimulating agents to patients with primary myelofibrosis after finding an unexpected association with transformation to leukemia in these patients. ...

Advisory panel backs drug for Huntington's chorea.(News)
January 15, 2008... BELTSVILLE, MD. -- The neuroleptic tetrabenazine will likely become the first drug approved in the United States for the management of Huntington's disease, following a federal advisory panel's unanimous vote supporting approval. ...

ESA risks in cancer patients under review.(News)(erythropoiesis-stimulating agents)(Brief article)
January 15, 2008... More evidence associating erythropoiesis-stimulating agents with increased tumor growth and mortality in patients with cancer is being reviewed at the Food and Drug Administration and could result in additional action by the agency. The...

Smoking cessation drug reports under review.(NEWS FROM THE FDA)
January 15, 2008... The Food and Drug Administration has issued an alert about postmarketing reports of suicidal thoughts, aggressive and erratic behavior, and drowsiness associated with varenicline, the smoking cessation drug marketed as Chantix. A notice on...

Warning labels required for nonoxynol 9 contraceptives.(NEWS FROM THE FDA)
January 15, 2008... The Food and Drug Administration is requiring manufacturers to include a warning label on all over-the-counter, stand-alone vaginal contraceptive and spermicide products containing nonoxynol 9, saying that the chemical does not protect against...

Thyrogen.(NEW & APPROVED)
January 15, 2008... Thyrogen (thyrotropin alfa for injection, Genzyme Corp.) A recombinant form of human thyroid-stimulating hormone (TSH) approved as an adjunctive treatment for radioiodine ablation of thyroid tissue remnants in patients who have...

Agento IC endotracheal tube.(NEW & APPROVED)
January 15, 2008... Agento IC endotracheal tube (C.R. Bard Inc.) An endotracheal tube coated with a thin film of silver indicated for airway management by oral or nasal intubation of the trachea for anesthesia, and in cases where duration of intubation is...

BRCA1 carriers need more frequent MRI, study suggests.(News)(Breast cancer type 1 susceptibility protein)(Magnetic resonance imaging)
January 15, 2008... SAN ANTONIO -- Annual breast cancer screening by mammography plus MRI is insufficient for BRCA1 mutation carriers, according to the midterm results of the Dutch MRI Screening Study. "It's clear the interval cancer rate is much higher in...

CKD patients are not receiving optimal care.(News)(chronic kidney disease)
January 15, 2008... SAN FRANCISCO -- A recent study indicates that about 41% of patients with chronic kidney disease receive their treatment solely from nonnephrologists, and about a third of these patients were not diagnosed, judging from the fact that their...

Unfair burden rests on PCPs.(LETTERS)(Letter to the editor)
January 15, 2008... Please lock the professors in their offices ("Medical Home Set to Move Forward," Dec. 1, 2007, p. 1). Everything drops in the primary care physicians' laps with no financial or logistical support. Deliver me from metrics! Between...

Being a single dad is ongoing struggle.(LETTERS)(Letter to the editor)
January 15, 2008... I became a single father of a bright young boy in the early 1990s ("Navigating Life as a Single Father," The Rest of Your Life, Oct. 15, 2007, p. 42). I felt displaced, alone, and of low worth as I struggled to see and spend time with my...

The right decision.(LETTERS)(Letter to the editor)
January 15, 2008... "Navigating Life as a Single Father" inspired me to write and share my experience so that other professionals might have some hope when faced with the possibility of losing their parental rights (The Rest of Your Life, Oct. 15, 2007, p. 42)....

Correction.(Correction notice)
January 15, 2008... In "Oral Purgatives Linked With Acute Kidney Injury" (Dec. 1, 2007, p. 1), the name and rank of Cpt. Frank P. Hurst, MC, USA, were incorrect. Also, he reported the findings in a poster but was not present at the meeting.

Exubera: right formulation, wrong time.(GUEST EDITORIAL)
January 15, 2008... Imagine you have just invented a revolutionary insulin delivery system for diabetes. Not only does it work as well as established short-acting insulin, but it has one huge advantage--it will free diabetes patients from injections forever!...

Diabetes education needs reevaluation.(GUEST EDITORIAL)
January 15, 2008... With the incidence of diabetes significantly increasing, especially type 2 diabetes in children and adolescents, there is a renewed interest in how to manage diabetes care. This issue is even more critical because many people with diabetes are...

Complete skin exam is key to finding melanoma.(Dermatology)
January 15, 2008... CHICAGO -- Early melanoma will often go undetected if patients do not undergo a full skin examination, according to a practice-based study presented at the annual meeting of the American Society for Dermatologic Surgery. In a series of 76...

Melanomas are often smaller than 6 mm.(Dermatology)(Brief article)
January 15, 2008... BALTIMORE -- Cutaneous lesions smaller than 6 mm in diameter may be more likely to be melanoma than previously thought, which may call into question commonly used screening criteria, according to findings presented at the annual meeting of the...

Actinic keratoses form and regress over time.(Dermatology)
January 15, 2008... AMSTERDAM -- The natural history of actinic keratoses involves high turnover and far greater lability than generally recognized, according to a first-of-its-kind study. "When you count three or four AKs on a person at time zero and come...

New diabetes patients have low fitness levels.(Endocrinology)(Clinical report)
January 15, 2008... NEW ORLEANS -- Physical activity and fitness levels are low in individuals with newly diagnosed type 2 diabetes, compared with reference populations, Kate J. Fitzsimons reported in a poster presentation at the annual meeting of the American...

Multilingual NDEP diabetes campaign.(Endocrinology)(National Diabetes Education Program )(Brief article)
January 15, 2008... The National Diabetes Education Program has launched a national campaign reaching out to health care professionals and their patients to emphasize the importance of comprehensive control of diabetes and cardiovascular disease. The "Control...