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BLOOD: Getting More Out of Cord Blood.
November 1, 2002... One obstacle to using cord blood more routinely as a source of stem cells in transplantation patients is that amount of stem cells in cord blood is often insufficient for adult recipients. Clinical trials have established that higher numbers of...
Prenatal Transplants Make Hosts Tolerant.
November 1, 2002... By combining prenatal transplants of blood-forming stem cells with manipulations of blood cells after birth, researchers at Children's Hospital of Philadelphia (34th Street and Civic Center Boulevard, Philadelphia, PA 19104-4399; Tel:...
Sickle Cell Grants Awarded.
November 1, 2002... St. Jude Children's Research Hospital (501St. Jude Place, Memphis, TN 38105; Tel: 901/495-3300; Website: www2. stjude.org) will receive a multi-million-dollar, 5-year grant to expand its sickle cell disease program. St. Jude is 1 of 10...
IMMUNE SYSTEM: Traffic Cop Cells Alleviate Colitis.
November 1, 2002... Enzo Biochem, Inc. (60 Executive Blvd., Farmingdale, NY 11735; Tel: 516/755-5500, Fax: 516/755-5569) researchers and collaborators have identified cells capable of alleviating immune mediated colitis. Their report, delivered at the American...
NERVOUS SYSTEM: High Efficiency Nerve Transformation.
November 1, 2002... For years, scientists have dreamed of using stem cells to replace neurons damaged by brain, spinal cord injury, or such neurodegenerative diseases as Parkinson's disease, Alzheimer's disease, or amyotrophic lateral sclerosis. A major stumbling...
LIVER: Hepatocytes Produce Therapeutic Proteins.
November 1, 2002... MultiCell Technologies Inc. (425 West 5th Ave., Suite 201, Escondido, CA 92025; Tel: 760/781-3916, Fax: 760/781-3919; Website: www.multicelltechnologies.com), a subsidiary of Exten Industries (Website: www.exten.com), has been awarded a Phase I...
Vesta Buys Liver Stem Cell Program.
November 1, 2002... Incara Cell Technologies, Inc. (3200 East Highway 54, Suite 300, P.O. Box 1428, Research Triangle Park, NC 27709; Tel: 919/558- 8688, Fax: 919/558-8686), a subsidiary of Incara Pharmaceuticals Corp., has completed the previously announced sale...
SKIN: Epidermal Cell Specific Promoter.
November 1, 2002... The European Patent Office has granted Patent 0625206 to Research Corporation Technologies (101 North Wilmot Rd., Suite 600,Tucson, AZ 85711; Tel: 520/748-4400, Fax: 520/748-0025; Website: www.rctech.com) for a human gene promoter that enables...
MESENCHYMAL STEM CELLS: Are All Mesenchymal Cells Equivalent?
November 1, 2002... Researchers from Genzyme Biosurgery (64 Sidney St., Cambridge, MA 02139-4136; Tel: 617/494-8484, Fax: 617/494-6561; Website: www.genzymebiosurgery.com), a division of Genzyme Corp., have published a paper that appears to cast new light on the...
Cells Hold Promise for Orthopedics.
November 1, 2002... "Adult stem cells have not only proven to be effective in bone healing today, they hold great promise for the future of orthopedics-especially in the areas of reconstructing all types of tissues, as well as improving the healing of diseased...
TISSUE ENGINEERING: Longer Arteries for Bypass.
November 1, 2002... Biomedical engineers at the Georgia Institute of Technology (Atlanta, GA 30332; Website: www.gatech.edu) are testing a device that, when implanted, mechanically lengthens an existing artery in patients preparing for coronary artery bypass...
ASSISTED REPRODUCTION Human Clones A'Plenty.
November 1, 2002... Clonaid (Tel: 702/497-9186; Website: www.clonaid.com) president Brigitte Boisselier claims that her organization has implanted several women with cloned embryos and will produce the world's first cloned human late this year or early in 2003....
GROWTH AND DIFFERENTIATION FACTORS Is Nicotine a Wonder Drug?
November 1, 2002... Could it be that nicotine is actually good for your heart? Cigarette manufacturer Phillip Morris is betting money on it.
Endovasc, Ltd. (15001 Walden Rd., Suite 108, Montgomery, TX 77356; Tel: 936/448-2222, Fax: 936/582-2250; Website:...
Factor Speeds Bone Regeneration.
November 1, 2002... According to study results published in the November 1 issue of the Journal of Spinal Disorders and Techniques, patients undergoing spinal fusion surgery using a new, genetically engineered protein (Infuse Bone Graft) had higher fusion rates...
DIAGNOSTICS: Glowing Cells Talk on Camera.
November 1, 2002... University of California, Los Angeles (405 Hilgard Ave., Box 951361, Los Angeles, CA 90095-1361; Tel: 310/825-4321; Website: www.ucla.edu) scientists led by Sanjiv Gambhir coupled the protein that makes fireflies glow with a device similar to a...
Q3DM Gets Scripps Technology.
November 1, 2002... Q3DM Inc. (10110 Sorrento Valley Rd., Suite B, San Diego, CA 92121; Tel: 866/366-0336; Website: www.q3dm.com) has been granted access to certain biosensor technology from the Scripps Research Institute (La Jolla, CA). Conditions of access were...
VACCINES: Cell-Based Treatment Works in Mice.
November 1, 2002... Researchers at Dendreon Corp. (291 North Bernardo Ave., Mountain View, CA; Tel: 415/964-6744, Fax: 415/964-7023; Website: www.dendreon.com) have demonstrated that a version of their anti- Her-2/neu cancer vaccine APC8024 is effective in the...
Education Slows Liver Tumors.
November 1, 2002... Enzo Biochem, Inc. (60 Executive Blvd., Farmingdale, NY 11735; Tel: 516/755-5500, Fax: 516/755-5569) said today that scientists in new preclinical studies have effectively suppressed the growth of, and in some cases eliminated, human liver...
Melanoma Phase II Trial Initiated.
November 1, 2002... IDM Immuno-Designed Molecules (172 rue de Charonne, 75011, Paris, France; Tel: +33 (0) 40 09 04 11, Fax: +33 (0) 1 40 09 04 25; Website: www.idm-biotech.com) has announced the launch of the Phase II trial of its therapeutic vaccine Uvidem...
INDUSTRY NEWS: Cord Blood Registry Gets $18 Million.
November 1, 2002... Cord Blood Registry (CBR, 1200 Bayhill Dr., Suite 301, San Bruno, CA 94066; Tel: 650/635-1420; Website: www.cordblood.com), which calls itself the world's largest accredited cord blood stem cell bank, received $18 million in new investment from...
GVAX Reacquired by Cell Genesys.
November 1, 2002... Cell Genesys, Inc. (342 Lakeside Dr., Foster City, CA 94404; Tel: 650/425-4400, Fax: 650/358-0803) has reacquired full commercial rights to GVAX lung cancer vaccines following the termination of its remaining license agreement with the...
Stem Cell Centers Multiply.
November 1, 2002... Despite Bush administration concerns about mistreatment of embryos and the stock market's dim view of regenerative medicine, new stem cell centers continue to open all over the world.
An advanced stem cell research center, aimed at...
CALENDAR.
November 1, 2002... December 2-4, 2002. Third Annual Conference on Regenerative Medicine. Contact: Mary Ann Liebert, Inc.; Tel: 800/M-LIEBERT, 914/834-3100, Fax: 914/834-3689; Email: hmatysko@liebertpub.com
December 4-6, 2002. Cell-Based Assays and Screening...