Primary Care Reports articles from December 2004

Primary Care Reports archives from December 2004

Management of constipation in adults.
December 1, 2004... Clinicians should become confident in management of constipation for numerous reasons, not the least of which is the sheer magnitude o[its prevalence in the ambulatory setting. Although the morbidity and mortality associated with other...

Toenail chromium in men with diabetes and cardiovascular disease.(Brief Article)
December 1, 2004... Source: Rajpathak M, et al. Diabetes Care. 2004;27(9):2211-2216. AT ONE TIME IN THE NUTRITION LITerature, chromium (CRM) was known as glucose tolerance factor. The role of CRM in glucose homeostasis was further corroborated by studies of...

Combination of fenofibrate and rosiglitazone and HDL cholesterol.(Brief Article)
December 1, 2004... Source: Normen L, et al. Diabetes Care. 2004;27(9):2241-2242. THE PRIMARY FOCUS OF LIPID CONtrol, even amongst diabetics, remains the LDL level, since most accumulated data provides good support for improvement in cardiovascular outcomes...

Outcomes for patients with diet-controlled diabetes.
December 1, 2004... Source: Hippisley-Cox J, Pringle M. Lancet. 2004;363:423-428. THE UNITED KINGDOM PROSPECTIVE diabetes Study (UKPDS) is the landmark clinical trial which forms the foundation for treatment of persons with type 2 diabetes (DM2). UKPDS showed...

Erythromycin and the risk of sudden death.(Brief Article)
December 1, 2004... Source: Ray W, et al. N Engl J Med. 2004;351:1089-1096. AGENTS WHICH ALTER CARDIAC repolarization have been associated with torsades de pointes. Although erythromycin (ERY) is a generally safe and efficacious medication, it does have the...

Acute hyperglycemia, mood, and cognitive performance in type 2 diabetics.(Brief Article)
December 1, 2004... Source: Sommerfield AJ, et al. Diabetes Care. 2004;27(10):2335-2340. HYPERGLYCEMIA IN DIABETES IS ASSOCIated with increased incidence of neuopathy, nephropathy, and retinopathy. Data about the effects of hyperglycemia upon cognitive...

Psychosocial risk factors and risk of acute MI.(Brief Article)
December 1, 2004... Source: Rosengren A, et al. Lancet. 2004;364:953-962. STUDIES IN NORTH AMERICA, Europe, and Japan have provided some support for the concept that emotional stress is a risk factor for coronary heart disease (CHD), but there is scanty...

ACE inhibitors and receptor blockers: which is inferior?
December 1, 2004... The first head-to-head comparison study of an ACE inhibitor and an angiotensin receptor blocker, to assess renoprotective effects in type 2 diabetes, has shown that the drugs are comparable in their benefit. It has been known for more than a...

The infection risk of acid-suppressing drugs.
December 1, 2004... Ever since cimetadine was first marketed in 1977, physicians have been concerned about the risk of infection associated with acid-suppressing drugs. Now researchers from the Netherlands have shown that concern is warranted, by demonstrating a...

Is rosuvastatin as safe as other statins?
December 1, 2004... Rosuvastatin (Crestor), AstraZeneca's entry into the high potency statin market, has not achieved marketshare comparable to Pfizer's atorvastatin (Lipitor) or Merck's simvastatin (Zocor). This, despite the facts that the drug is very potent and...

Which estrogen preparation is the safest?
December 1, 2004... Is esterified estrogen safer than conjugated equine estrogen? At least with regard to venous thrombosis, the answer may be yes, according to a recent study. Group Health Cooperative in Washington State, a large HMO, switched their patients from...

FDA actions.(Brief Article)
December 1, 2004... Serono has been given approval to market recombinant human luteinizing hormone (Luveris) for the treatment of infertility in women. The drug, which was granted orphan status, has been available in more than 60 countries for several years. ...