OB/GYN Clinical Alert articles from October 2003

OB/GYN Clinical Alert archives from October 2003

Oral contraceptive mortality.( )(Author Abstract)
October 1, 2003... VESSEY, PAINTER, AND YEATES FROM THE UNIVERSITY OF Oxford used the prospective cohort of women enrolled in the Oxford Family Planning Association Study to assess mortality in users and nonusers of oral contraceptives. By the end of the year...

Management of port-site metastasis after laparoscopic surgery for ovarian cancer.( )(Author Abstract)
October 1, 2003... Synopsis: Port-site metastasis after laparoscopic surgery during chemotherapy, or when adequate chemotherapy has been given, is usually associated with poor outcome. ********** IN AN ATTEMPT TO DEFINE THE CLINICAL FEATURES AND...

Accuracy of laparoscopic diagnosis of PID.(pelvic inflammatory disease)(Author Abstract)
October 1, 2003... Synopsis: Compared to histopathology, visual diagnosis of PID is neither accurate nor reproducible. ********** MOLANDER AND COLLEAGUES EVALUATED THE ABILity of 3 obstetrician/gynecologists (12 years average length of time in practice)...

Prevention of breast cancer with tamoxifen.( )(Author Abstract)
October 1, 2003... Synopsis: Only 5% of white women and 0.6% of black women are potential candidates for tamoxifen chemoprevention. ********** FREEDMAN AND COLLEAGUES FROM THE NATIONAL Cancer Institute estimated the total number of US women in the year...

Intraperitoneal radioactive phosphorus (32P) vs observation after negative second-look laparotomy for stage III ovarian carcinoma.( )(Author Abstract)
October 1, 2003... Synopsis: Intraperitoneal chromic phosphate did not decrease the risk of relapse or improve survival for patients with stage III epithelial ovarian cancer after a negative second-look surgery. ********** IN A GYNECOLOGIC ONCOLOGY GROUP...

Use of OCPs to eliminate withdrawal bleeding.(Abstract & Commentary)(oral contraceptives)
October 1, 2003... Synopsis: Daily administration of a low-dose oral birth control pill results in significantly fewer bleeding days. ********** MILLER AND HUGHES FROM THE UNIVERSITY OF Washington randomized 79 patients to either cyclic or daily oral...

Death by a thousand indignities: the saga of HRT.(Special Feature)(hormone replacement therapy)
October 1, 2003... THIS WEEK THERE WERE 2 ARTICLES IN THE New England Journal of Medicine that explored the link between postmenopausal hormone use and heart disease. The first article was the final analysis of the Prempro[R] arm of the WHI. The other was an...

Seasonale: a revolutionary contraceptive.(Audio Conference)
October 1, 2003... EXTENDED HORMONAL CONTRACEPTION IS DRAWING dramatic attention due to the desire of many women to reduce or eliminate the number of withdrawal bleeds associated with current birth control methods. The first extended-use oral contraceptive,...

CME question.(continuing medical education )
October 1, 2003... 10. Effective consolidation therapy--treatment that reduces relapse risk after completion of primary surgery plus chemotherapy--is: a. whole abdominal radiotherapy. b. single-agent chemotherapy. c. combination chemotherapy. d....

A strategy to reduce cardiovascular disease by more than 80 percent.(Author Abstract)
October 1, 2003... DESPITE IMPRESSIVE RESULTS IN cardiovascular risk reduction by applying an individual treatment (eg, statin, antihypertensive), the effect of multiple risk factor reduction has been much more elusive to quantify. Wald and Law suggest that the...

Pearly penile papules: still no reason for uneasiness.(Author Abstract)
October 1, 2003... IT IS NOT UNCOMMON FOR ADULT MEN TO preset to clinicians with lesions on their penis, which ultimately turn out to be pearly penile papules (PPP). These lesions appear around the margins of the glans and have been sometimes mistaken for...

The epidemiology of major depressive disorder.(Author Abstract)
October 1, 2003... THE FIRST MAJOR NATIONAL POPULATION survey to establish the demographics of depression using DSM III criteria occurred 1990-1992 and reported a lifetime prevalence of 14.9%, with 12 month prevalence of 8.6%. Since that report, an evolution of...

Urinary tetrahydroaldosterone as a screen for aldosteronism.(Author Abstract)
October 1, 2003... IT HAS RECENTLY BEEN SUGGESTED THAT a substantial minority of persons with hypertension--as many as 1 out of 7 or 8--suffer overlooked primary hyperaldosteronism (PHA) as an etiology. Although unprovoked hypokalemia, when present, is a useful...

Finasteride and prostate cancer.(Author Abstract)
October 1, 2003... IT IS APPARENT THAT ANDROGENIC HORmones, in particular dihydrotestosterone (DHT), are participants in the generation of prostate cancer (PCA). Since 5-alpha-reductase inhibitors (5ARI) like finasteride (Proscar) and dutasteride (Avodart) are...

Impermeable bed covers in patients with allergic rhinitis.(Brief Article)
October 1, 2003... SUFFERERS OF ALLERGIC RHINITIS (ALR) are often sensitive to a variety of allergens, of which house-dust mites are a commonplace troublemaker. The 2 most common offending house-dust antigens, Dermatophagoides pteronyssinus and D farinae, are...

Vardenafil will compete for share of ED market.(Pharmacology Watch)
October 1, 2003... The FDA has approved vardenafil (Levitra--Bayer and GlaxoSmithKline) for the treatment of erectile dysfunction in men. Vardenafil joins sildenafil (Viagra) as the only 2 drugs approved for this indication in this country. Vardenafil was...