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OB/GYN Clinical Alert articles from November 2003
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OB/GYN Clinical Alert archives from November 2003
The WHI reports on fracture and gynecologic cancers.(Women's Health Initiative)(Abstracts & Commentary)
November 1, 2003... THE WOMEN'S HEALTH INITIATIVE (WHI) REPORTS THAT ESTROGEN-progestin therapy reduces fractures, but the number of gynecologic cancers observed precludes a definitive statement on the risk of endometrial and ovarian cancers.
The report on...
'It's deja vu all over again' *.(Abstract & Commentary)
November 1, 2003... Synopsis: Weekly injections of 17 alpha-hydroxyprogesterone caproate resulted in a substantial reduction in the rate of recurrent preterm delivery among women who were at particularly high risk for preterm delivery and reduced the likelihood of...
External version: can we spare patients from a cesarean section?(Special Feature)
November 1, 2003... AS POINTED OUT IN PREVIOUS OB/GYN Clinical Alerts, about 1 in 4 patients in the United States are delivered by cesarean section, a procedure still classified as a "major operation" Newer figures from year 2002 are not available, but the...
CME questions.
November 1, 2003... 13. The following statements are true regarding the WHI reports on fractures and gynecologic cancers except:
a. A statistically significant decrease in the treatment arm occurred in all fractures associated with osteoporosis.
b. Not...
Generic Paxil scheduled to hit market this fall.
November 1, 2003... A generic form of paroxetine (Paxil--GlaxoSmithKline) will soon be on the market. The drug marks the second SSRI antidepressant to go generic after fluoxetine (Prozac) last year. US sales of Paxil reached $2.23 billion last year, and the...
Insulin plus metformin vs triple oral therapy in type 2 diabetes.(Brief Article)
November 1, 2003... Source: Schwartz S, et al. Diabetes Care. 2003;26:2238-2243.
PATIENT PREFERENCES OFTEN DIRECT the use of multiple oral agents in an attempt to control DM2, in an effort to avoid using insulin. Trial data to date have not provided specific...
ARB and ACE-I in diabetic nephropathy.(angiotensin II receptor blockers, ACE inhibitors)(Brief Article)
November 1, 2003... Source: Rossing K, et al. Diabetes Care. 2003;26:2268-2274.
IT HAS BEEN CONSISTENTLY DEMONSTRATED that treatment of albuminuria in diabetics with either an ACE inhibitor (ACEI) or angiotensin II receptor blocker (ARB) produces reductions in...
Low-glycemic index diets and diabetes.(Brief Article)
November 1, 2003... Source: Brand-Miller J, et al. Diabetes Care. 2008;26;2261-2267.
THE EFFECT OF LIFESTYLE MODULATION in diabetes is sometimes overshadowed by the favorable effect of pharmacotherapy, despite the data indicating for instance that diet and...
Ultralow-dose estrogen and bone in older women.(Brief Article)
November 1, 2003... Source: Prestwood KM, et al. JAMA. 2003;290:1042-1048.
HORMONE REPLACEMENT THERAPY (HRT), has been found to have favorable effects upon osteoporosis and fracture risk in postmenopausal women. Unfortunately, this bone benefit is at the...
Effect of intensity of oral anticoagulation in atrial fibrillation.(Brief Article)
November 1, 2003... Source: Hylek EM, et al. N Engl J Med. 2003;349:1019-1026.
THE VALUE OF WARFARIN ANTICOAGULATION (WAC) in atrial fibrillation (AF) to prevent ischemic stroke is well established. Despite therapeutic levels of WAC, however, some AF patients...
Patient knowledge and awareness of hypertension.(Brief Article)
November 1, 2003... Source: Alexander M, et al. J Clin Hypertens. 2003;5:254-260.
DESPITE A DIVERSITY OF EXCELLENT pharmacotherapeutic tools for treating hypertension (HTN), national population surveys continue to indicate that there is much room for...