OB/GYN Clinical Alert articles from May 2004

OB/GYN Clinical Alert archives from May 2004

More from the Women's Health Initiative.(Special Report)
May 1, 2004... In this feature, Leon Speroff, MD, discusses the most recent findings from the Women's Health Initiative study. THE LATEST NEWS FROM THE WOMEN'S HEALTH INITIATIVE (WHI) includes 3 noteworthy reports: the news release announcing the...

Restaging surgery for women with borderline ovarian tumors: results of a French multicenter study.(Abstract & Commentary)
May 1, 2004... Synopsis. Women who initially were diagnosed with Stage IA disease and who had serous borderline tumors or underwent cystectomy appeared to derive the most benefit from restaging surgery. Nonetheless, the indications for restaging surgery...

Non-invasive approach to prenatal diagnosis.(Special Feature)
May 1, 2004... THE AMERICAN COLLEGE OF OBSTETRICS AND GYNEcology issued a statement many years ago that has been ingrained into the thinking of providers caring for patients of "advanced maternal age." The recommendation was that all pregnant women 35 years...

CME questions.(Brief Article)
May 1, 2004... 8. With which of the following is it possible to drop the risk for Down syndrome for a given patient below the risk of amniocentesis? a. Triple screen b. Quad screen c. Integrated test d. Genetic sonogram e. All of the...

Migraine and sub-clinical brain lesions.(Brief Article)
May 1, 2004... Source: Kruit MC, et al. JAMA. 2004;291:427-434. THE DATA ON THE RELATIONSHIP between migraine and other vascular events such as stroke have been conflicting, although in some populations (such as young women smokers who suffer migraine...

Memantine treatment in Alzheimer Disease.(Brief Article)
May 1, 2004... Source: Tariot PN, et al. JAMA. 2004;291:317-324. MEMANTINE (MEM) IS THE FIRST clinically available NMDA receptor antagonist with demonstrated clinical efficacy and an acceptable adverse event profile for persons with Alzheimer disease...

Casual postprandial glucose levels in type 2 diabetes management.(Brief Article)
May 1, 2004... Source: El-Kebbi IM, et al. Diabetes Care. 2004;27:335-339. TIGHT CONTROL OF TYPE DIAbetes (DM2) has been proven to reduce microvascular complications. Use of the hemoglobin Alc to assess long-term control is standard, but for modulation of...

Exemestane after tamoxifen therapy in breast cancer.(Brief Article)
May 1, 2004... Source: Coombes RC, et al. N Engl J Med. 2004;350(11):1081-1092. TAMOXIFEN (TAM) IS WELL ESTABlished to reduce, over 5 years, both risk of breast cancer (BCA) recurrence (47%) and mortality (26%) among women who have undergone surgery for...

An analysis of how long patients remain on various antihypertensive therapies .(Brief Article)
May 1, 2004... Source: Eaposti LD, et al. J Clin Hypertens. 2004;6:76-84. THE TERM 'DRUG EFFICACY' IS TECHnically Intended to reflect impact of an agent on a designated end point in a study population participating in a clinical trial. 'Drug...

Association of endothelial dysfunction with insulin resistance and carotid wall thickening in hypertension.(Brief Article)
May 1, 2004... Source: Suzuki M, et al. Am J Hypertens. 2004;17:228-232. ENDOTHELIAL DYSFUNCTION (END) IS a fundamental defect in essential hypertension (HTN) and is closely associated with carotid wall thickening (CWT), a consistent marker for early...

Atherosclerosis reversed with lipid-lowering drugs.
May 1, 2004... When it comes to treating lipids in patients with heart disease, the mantra may be, The lower the LDL, the better." Data from the multicenter Reversal of Atherosclerosis with Aggressive Lipid Lowering (REVERSAL) trial indicate that aggressive...

Positive alendronate data in osteoporosis.(Brief Article)
May 1, 2004... Does alendronate prevent fractures after 10 years of therapy? According to a new multicenter placebo-controlled trial, the drug is effective and safe over 10 years in women with osteoporosis. Data from the study are from a follow-up of 2...

NSAIDs for myocardial infarction.(Nonsteroidal anti-inflammatory agents)(Brief Article)
May 1, 2004... Nonaspirin NSAIDs, especially ibuprofen and naproxen, may protect against myocardial infarction in patients who are not taking aspirin. Researchers from Pennsylvania conducted a case-control study with cases of first, nonfatal MI identified...

Four-hour window for CAP patients.(community-acquired pneumonia )(Brief Article)
May 1, 2004... Medicare patients with community-acquired pneumonia (CAP) fare better if they receive their first dose of antibiotics within 4 hours of hospitalization, according to new study. The records of nearly 14,000 Medicare patients admitted for CAP,...

FDA actions.(Brief Article)
May 1, 2004... Rofecoxib (Vioxx) has been approved for the treatment of migraine attacks with or without aura in adults. The approval was based on a large study that showed that the single dose of rofecoxib, either 25 or 50 mg, effectively reduced migraine...