OB/GYN Clinical Alert articles from May 2003

OB/GYN Clinical Alert archives from May 2003

The WHI and quality of life.
May 1, 2003... ABSTRACT & COMMENTARY AN ANALYSIS OF THE EFFECT ON MEMORY, SLEEPING, AND MENTAL status of daily estrogen-progestin administration to post-menopausal women, based on data from the discontinued arm of the Women's Health Initiative (WHI), was...

A phase II study of docetaxel in paclitaxel-resistant ovarian and peritoneal carcinoma: a gynecologic oncology group study.
May 1, 2003... ABSTRACT & COMMENTARY Synopsis: Docetaxel is active in paclitaxel-resistant ovarian and peritoneal cancer, but, in view of significant hematologic toxicity, further study is warranted to ascertain its optimal dose and schedule. Source:...

Sacrospinous cervicocolpopexy with uterine preservation for elderly women.
May 1, 2003... ABSTRACT & COMMENTARY Synopsis: Sacrospinous cervicocolpopexy with uterine conservation in elderly women with prolapse can be used to avoid the morbidity of hysterectomy. Source: Hefni M, et al. Am J Obstet Gynecol. 2003;188:645-650....

Oral contraceptives and hypertension.
May 1, 2003... ABSTRACT & COMMENTARY Synopsis: The use of oral contraceptives in women with hypertension produced higher blood pressures and poor control of blood pressure. Source: Lubianca JN, et al. Contraception. 2003;67: 19-24. LUBIANCA AND...

Women's perceptions about treatment decision-making for ovarian cancer.
May 1, 2003... ABSTRACT & COMMENTARY Synopsis: Women with advanced epithelial ovarian cancer did not describe the treatment decision-making process as shared; rather, they described an interaction that was directed by their physician. Source: Elit L,...

Alternatives to menopausal hormone therapy. (Special Feature).
May 1, 2003... ONE OF THE BENEFITS THAT HAS COME FROM THE release of the data from the Prempro[R] arm of the Women's Health Initiative (WHI) on July 9, 2002, has been a re-evaluation of the pros and cons of menopausal hormonal therapy. In undertaking this...

CME questions.
May 1, 2003... 12. Which of thc following is not advocated for slowing the aging process? a. DHEA b. Bisphosphonates c. Melatonin d. Diet e. Exercise 13. The following statements are true of the Women's Health Initiative except:...

Use of hip protectors in nursing homes. (Clinical Briefs in Primary Care).
May 1, 2003... Source: Meyer G, et al. BMJ. 2003;326:76-78. DESPITE THE FACT THAT USE OF HIP protectors (HIP) has demonstrated excellent outcomes reduction when used among elderly persons ie, as much as a 50% reduced incidence of hip fractures, actual use...

Disclosing unanticipated Outcomes and medical errors. (Clinical Briefs in Primary Care).
May 1, 2003... Source: O'Connell D, et al. J Clin Outcomes Man. 2003;10(1):25-29. ACCORDING TO THE 1999 INSTITUTE OF Medicine report, medical errors are an important cause of loss of life, resulting in as many as 98,000 deaths annually in the United...

Non-invasive positive pressure ventilation to treat respiratory failure resulting from exacerbations of COPD. (Clinical Briefs in Primary Care).
May 1, 2003... Source: Lightowler JV, et al. BMJ. 2003;326:185-187. WTHE TRADITIONAL INTER ventions (eg, bronchodilators, steroids, antibiotics, oxygen) for COPD exacerbation are insufficient to reverse clinical deterioration, clinicians typically rely...

Effect of ibuprofen on cardioprotective effect of aspirin. (Clinical Briefs in Primary Care).
May 1, 2003... Source: MacDonald TM, Wei L. Lancet. 2003;361:573-574. A SUBSTANTIAL AMOUNT OF LITERAture supports the efficacy of aspirin (ASA) for primary and secondary prevention of cardiovascular disease. The benefits of aspirin for reduction of...

Antidepressant drug treatment in depressive disorders. (Clinical Briefs in Primary Care).
May 1, 2003... Source: Geddes JR, et al. Lancet. 2003;361:653-661. PHARMACOTHERAPY FOR DEPRESSION IS generally recognized to be effective to produce remission in the majority of sufferers. The recommended duration of treatment of depression has undergone...

Adverse drug events among the elderly in the ambulatory setting. (Clinical Briefs in Primary Care).
May 1, 2003... Source: Gurwitz JH, et al. JAMA 2003;289:1107-1116. WHEN ONE CONSIDERS THAT MORE than 90% of persons older than age 65 use at least 1 medication per week, and that more than 40% of these individuals use 5 or more medications per week, it...

Counterfeit Procrit uncovered by FDA surveillance. (Pharmacology Watch).
May 1, 2003... In one of the more bizarre stories of the year, the FDA has uncovered files of counterfeit Procrit (epoetin alfa--Johnson & Johnson) in routine surveillance. To make matters worse, the fake vials have been contaminated with bacteria and many...