OB/GYN Clinical Alert articles from March 2002

OB/GYN Clinical Alert archives from March 2002

What vitamins should I be taking, doctor? (Abstract & Commentary).
March 1, 2002... IN THE PAST, PHYSICIANS HAVE BEEN TAUGHT THAT HEALTHY INDIVIDUALS can meet their vitamin requirements by eating a well-balanced diet. Nonetheless, nearly one third of the US population consumes some type of vitamin supplement on a regular...

Response and survival in patients with serous ovarian tumors of low malignant potential. (Abstract & Commentary).
March 1, 2002... Synopsis: Patients with progressive or recurrent serous ovarian tumors of low malignant potential have a long interval from diagnosis to progression and from progression to death, resulting in extended overall survival. Source: Crispens...

Interpregnancy intervals: How long is long enough between pregnancies? (Abstract & Commentary).
March 1, 2002... Synopsis: Although the incidences of adverse birth outcomes in general were higher in African-American women, the odds ratios for each adverse outcome at various pregnancy intervals were remarkably similar. Source: Zhu BP, et al. Am J...

Melatonin treatment for age-related insomnia. (Abstract & Commentary).
March 1, 2002... Synopsis: In older people with insomnia, a 0.3-mg dose of melatonin improved sleep efficiency. Source: Zhdanova TV, et al. J Clin Endocrinol Metab. 2001;86:4727-4730. MELATONIN IS UNDENIABLY THE BEST REFLECTION of the central clock,...

Effect of BRCA mutations on the length of survival in epithelial ovarian tumors. (Abstract & Commentary).
March 1, 2002... Synopsis: Survival of patients with ovarian cancer is affected by BRCA germline mutation, with BRCA1/BRCA2 carriers with ovarian cancer surviving longer than noncarriers. Source: David BY, et al. J Clin Oncol. 2002;20: 462-466. BEN...

Estrogen treatment of postmenopausal women with unstable angina. (Special Feature).
March 1, 2002... SCHULMAN AND COLLEAGUES FROM BALTIMORE, Pittsburgh, and Sao Paulo, Brazil, conducted a randomized, double-blind, placebo-controlled study of 293 women with unstable angina. Unstable angina was defined as 10 or more minutes of pain with...

Oral triptans in acute migraine treatment. (Clinical Briefs in Primary Care).(sumatriptan, eletriptan, frovatriptan, rizatriptan, and almotriptan)
March 1, 2002... Source: Ferrari MD, et al. Lancet. 2001;358:1668-1675. MIGRAINE IS A COMMONPLACE DISORDER that typically results in recurrent attacks of disabling headache. Triptans have become the foundation of abortive therapy for most migraneurs, yet...

Simvastatin, niacin, and antioxidant vitamins for the prevention of CAD. (Clinical Briefs in Primary Care).(coronary artery disease)
March 1, 2002... Source: Brown BG, et al. N Engl J Med. 2001;345:1583-1592. IT HAS BEEN SUGGESTED THAT CARDIOVAscular risk is separately and independently related to both changes in LDL and HDL. The oft-quoted relationship between lipid subfractions...

Decreased rate of coronary restenosis after lowering of plasma homocysteine levels. (Clinical Briefs in Primary Care).
March 1, 2002... Source: Schnyder G, et al. N Engl J Med. 2001;345:1593-1600. THE POTENTIAL ETIOLOGIC RELATION-ship of homocysteine (HCST) to cardiovascular disease end points has generated much recent scrutiny. There has not been a major clinical trial...

Identification and fracture outcomes of undiagnosed low BMD in postmenopausal women. (Clinical Briefs in Primary Care).(bone mineral density)
March 1, 2002... Source: Siris ES, et al. JAMA. 2001; 286:2815-2822. BONE MINERAL DENSITY (BMD) MEA-surement by dual-energy x-ray absorptiometry (DEXA) is currently the gold standard for identification of osteoporosis (OSPS) and osteopenia (OSPN). Measuring...

Comparison of cefuroxime with or without intranasal fluticasone for the treatment of rhinosinusitis. (Clinical Briefs in Primary Care).
March 1, 2002... Source: Dolor RJ, et al. JAMA. 2001;286:3097-3105. THE USE OF INTRANASAL STEROIDS (INS) is appropriate foundation therapy for many patients with allergic rhinitis. Since INS produce reduction in inflammation and edema of the nasal mucosa...

Lack of clinical significance of early ischemic changes on CT in acute stroke. (Clinical Briefs in Primary Care).
March 1, 2002... Source: Patel SC, et al. JAMA. 2001;286:2830-2838. IT HAS BEEN RECOMMENDED, LARGELY based upon the National Institute of Neurological Disorders and Stroke (NINDS) study, that patients presenting within 3 hours of stroke onset be considered...