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Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the women's health initiative randomized controlled trial.(Abstract & Commentary)
June 1, 2004... Synopsis: The use of CEE conferred protection against fracture without an increase in breast cancer but with an increased risk of hypertension, stroke, and venous thromboembolism.
Source: The WHI Steering Committee. JAMA....
Adjuvant radiation determined for intermediate risk endometrial cancer! Or has it?
June 1, 2004... THE STRENGTH OF A CLINICIAN'S RECOMMENDATION for patient care is greatest in data generated through carefully conducted experimental studies. In many cases, this quality of data is generated from randomized clinical trials where a novel...
CME questions.(continuing medical education)
June 1, 2004... 11. Which of the following techniques is best in reducing pain associated with Pipelle biopsies?
a. Oral naproxen sodium
b. Intrauterine installation of 2% lidocaine
c. Paracervical block
d. Pudendal block
e. a and b
...
Antihypertensive treatment and measurement at home or in the physician's office.(Brief Article)
June 1, 2004... Source: Staeesen JA, et al. JAMA. 2004;291:955-964.
A NOT-INSUBSTANTIAL MINORITY OF persons carrying a diagnosis of hypertension (HTN) actually have stress-induced transient episodes of HTN in clinicians' offices, which we call "white coat...
Inactivated intranasal influenza vaccine and the risk of Bell's Palsy.(Brief Article)
June 1, 2004... Source: Mutsch M, et al. N Eng J Med. 2004;350:896-903.
LATE IN 2000, THE SWISS DRUG Monitoring Center and others noted numerous reports of Bell's palsy in persons who had received NFLU. To better study the relationship between NFLU and...
Topiramate for migraine prevention.(Brief Article)
June 1, 2004... Source: Brandes JL, et al. JAMA. 2004;291(8):965-973.
SOME PATIENTS REMAIN DISSATISFIED with or intolerant of available migraine treatments. Early studies have found that topiramate (TOP), an antiepileptic agent, is efficacious for migraine...
Computed tomographic colonography (Virtual colonoscopy).(Brief Article)
June 1, 2004... Source: Cotton PB, et al. JAMA. 2004;291:1713-1719.
SCREENING FOR COLON CANCER (Cca) has not reached the same level of popular adherence as seen with, for instance, prostate cancer screening by PSA. Although colonoseopy (COL) is highly...
Ejaculation frequency and subsequent risk of prostate cancer.(Brief Article)
June 1, 2004... Source: Leitzmann MF, et al. JAMA. 2004;291:1578-1586.
PROSTATE CANCER (PCA) HYPOTHETICALLY could be related to sexual activity. For instance, if men who seek sexual activity more often have higher testosterone levels, and such levels were...
Different combinations of Bupropion SR dose and behavioral treatment for smoking cessation.(sustained relaease)(Brief Article)
June 1, 2004... Source: Javitz HS, et al. Am J Manag Care. 2004;10:217-226.
THE SINGLE MOST EFFECTIVE PHARMACEUTICAL intervention which results in sustained smoking cessation is bupropion (BUP). The most often-used treatment regimen requires BUP 150 mg/d...
Missing link between vaccines and diabetes.(statins and the risk of breast cancer)(warning on irritable bowel syndrome drugs)
June 1, 2004... A large cohort study from Denmark suggests no link between childhood vaccines and type I diabetes. The potential for such a link has been of concern for years because of the association between certain infections and the development of type I...