OB/GYN Clinical Alert articles from June 2003

OB/GYN Clinical Alert archives from June 2003

Trends in incidence rates of invasive lobular and ductal breast carcinoma.
June 1, 2003... ABSTRACT & COMMENTARY THE RATIONALE FOR THE PRESENT INVESTIGATION WAS THAT A growing number of studies have reported that the risk of breast cancer associated with use of combined hormone replacement therapy (CHRT) differs by histological...

Hormonal contraception and cervical cancer.
June 1, 2003... ABSTRACT & COMMENTARY Synopsis: An increased risk of cervical cancer is associated with long durations of use of hormonal contraceptives. Source: Smith JS, et al. Lancet. 2003;361:1159-1167. A TEAM OF EPIDEMIOLOGISTS PERFORMED A...

Does cesarean delivery prevent anal incontinence?
June 1, 2003... ABSTRACT & COMMENTARY Synopsis: Severe anal incontinence occurs after elective cesarean delivery as well as vaginal delivery, suggesting that pregnancy itself may lead to pelvic floor disorders. Source: Lal M, et al. Obstet Gynecol....

Prospective study of alcohol consumption and risk of dementia in older adults.
June 1, 2003... ABSTRACT & COMMENTARY Synopsis: Compared with abstention, consumption of 1-6 drinks weekly of alcoholic beverages was associated with a lower risk of dementia among adults older than 65 years. Source: Mukamal KJ, et al. JAMA....

Should every patient have second-trimester biochemical testing regardless of amniocentesis? (Special Feature).
June 1, 2003... WE HAVE HAD MANY PATIENTS DECLINE TRIPLE OR quad screen testing because "it would not be useful since I am having an amniocentesis" or "the test has too many false positives." Often these statements represent paraphrased comments made by their...

Detection of Alzheimer's disease and dementia in the preclinical phase. (Clinical Briefs in Primary Care).(Brief Article)
June 1, 2003... Source: Palmer K, et al. BMJ. 2003; 326:245-247. ALZHEIMER'S DISEASE (AD) IS THE most common form of dementia in America, but often escapes clinical attention until symptoms compromise quality of life, activities of daily living, or safety....

Shoe design and plantar pressures in neuropathic feet. (Clinical Briefs in Primary Care).(Brief Article)
June 1, 2003... Source: Praet S, et al. Diabetes Care. 2003;26:441-445. CLINICIANS HAVE TRIED A VARIETY OF maneuvers to reduce the incidence and effect of neuropathic foot ulcers in an attempt to reduce their subsequent morbidity. Since a substantial...

TSH in assessment of hypothyroidism. (Clinical Briefs in Primary Care).(thyroid stimulating hormone)(Brief Article)
June 1, 2003... Source: Meier C, et al BMJ 2003; 326:311-312. ALTHOUGH THERE IS GOOD AGREEment that thyroid stimulating hormone (TSH) is the most appropriate indicator of hypothyroidism, it is little understood whether absolute levels of TSH correlate...

Oral Vitamin D3 supplementation on fractures and mortality. (Clinical Briefs in Primary Care).(Brief Article)
June 1, 2003... Source: Trivedi DP, et al. BMJ. 2003;326:469-472. DESPITE RECENT ENHANCED CLINIcian and public awareness, prevention and treatment goals for osteoporosis (OSPS) remain inadequately fulfilled. A variety of lifestyle and pharmacologic tools...

Oral opioid therapy for chronic peripheral and central neuropathic pain. (Clinical Briefs in Primary Care).(Brief Article)
June 1, 2003... Source: Rowbotham M, et al. N Engl J Med. 2003;348:1223-1232. NEUROPATHIC PAIN (NPP) IS OFTEN described as "opioid resistant," based upon some limited human and animal studies, On the other hand, parenteral opioid analgesia has produced...

Tacrolimus ointment vs. topical corticosteroids in atopic dermatitis. (Clinical Briefs in Primary Care).(Brief Article)
June 1, 2003... Source: Ellis C, et al. J Am Acad Dermatol. 2003;48:553-563. FOR SEVERAL DECADES THE MAINSTAY of management of atopic dermatitis (AD) has been corticosteroids (CSD), usually administered topically. When AD is mild-moderate, low, and...

Pneumococcal vaccine ineffective at CAP prevention. (Pharmacology Watch).(community-acquired pneumonia)
June 1, 2003... Pneumococcal vaccine protects older adults from developing pneumococcal bacteremia but does not prevent community-acquired pneumonia (CAP), according to a new study from Group Health Cooperative in Seattle. The study reviewed records of more...