OB/GYN Clinical Alert articles from August 2004

OB/GYN Clinical Alert archives from August 2004

The WHI and cognition.(Abstracts & Commentary)(Women's Health Initiative)
August 1, 2004... THE WOMEN'S HEALTH INITIATIVE REPORTED THEIR RESULTS ON cognition and dementia combining the canceled estrogen-only arm with the canceled estrogen-progestin arm of the randomized trial; the data are derived from an ancillary study of the trial...

Vasa previa: the effect of prenatal diagnosis on outcomes.(Abstract & Commentary)
August 1, 2004... Synopsis: Good outcomes with vasa previa depend primarily on prenatal diagnosis and cesarean delivery at 35 weeks of gestation or earlier should rupture of membranes, labor, or significant bleeding occur. Source: Oyelese Y, et al. Obstet...

Prediction of optimal vs suboptimal cytoreduction of advanced-stage serous ovarian cancer with the use of microarrays.(Abstract & Commentary)
August 1, 2004... Synopsis: These data support the hypothesis that favorable survival that is associated with optimal debulking of advanced ovarian cancers is due to, at least in part, the underlying biologic characteristics of these cancers. Source:...

Postmenopausal hormone therapy and the risk of ovarian cancer.(Special Feature)
August 1, 2004... THE CANCELED ESTROGEN-PROGESTIN ARM OF THE Women's Health Initiative reported an increase in ovarian cancer that was not statistically significant, prompting the authors to say: "The possibility of an increased risk of ovarian cancer incidence...

CME question.
August 1, 2004... 4. The following statements are true regarding the WHIMS study from the WHI: a. WHIMS enrolled only older postmenopausal women. b. Postmenopausal women treated with hormone therapy have an increased risk of dementia. c. WHIMS and...

Glucose metabolism and coronary heart disease in patients with normal glucose tolerance.(Brief Article)
August 1, 2004... Source: Sasso FC, et al. JAMA. 2004;291:1857-1863. THERE IS A CLEARLY ESTABLISHED relationship between frank diabetes (DM) and increased vascular risk, especially coronary heart disease. Whether more modest perturbations in glucose...

Evidence of airborne transmission of the severe acute respiratory syndrome virus.(Brief Article)
August 1, 2004... Source: Yu ITS, et al. N Engl J Med. 2004;350:1731-1739. FOR THE MOMENT, THE IMMEDIATE threat of Severe Acute Respiratory Syndrome virus (SARS) appears to have passed in the United States. The serious morbidity and mortality of the virus...

Alcohol intake and risk of incident gout in men.(Brief Article)
August 1, 2004... Source: Choi HK, et al. Lancet. 2004; 363:1277-1281. THE ASSOCIATION BETWEEN GOUT AND alcohol consumption has been oft quoted, though never previously established by a prospective trial. It has been confirmed that alcohol loading acutely...

Prevention of strokes by successful carotid endarterectomy in patients without recent neurological symptoms.(Brief Article)
August 1, 2004... Source: MRC Asymptomatic Carotid Surgery Trial Collaborative Group. Lancet. 2004;363:1491-502 CLEAR-CUT BENEFIT FROM CAROTID endarterectomy for secondary prevention of stroke amongst persons with carotid stenosis who have suffered a...

Cox-2 inhibitors vs nonselective NSAIDs and CHF outcomes in elderly patients.(Brief Article)
August 1, 2004... Source: Mamdani M, et al Lancet. 2004;363:1751-1756. USE OF NON-SELECTIVE NSAIDS, CAN induce retention of Na+, K+, and water. Whether selective Cox-2 inhibitors (COXIBs) are fraught with an equally daunting likelihood of potential for fluid...

Interventions for the prevention of falls in older adults.(Brief Article)
August 1, 2004... Source: Chang JT, et al BMJ USA. 2004;4:223-226. ONE-THIRD OF PERSONS OLDER THAN age 65, and one-half of those older than 80 sustain a fall annually, many of which result in hospital admission, impairment of mobility, or even death. A...