Archives of Disease in Childhood articles from October 2001

Archives of Disease in Childhood archives from October 2001

MMR vaccine--worries are not justified.(measles-mumps-rubella vaccine side effects)
October 1, 2001... The advocates of Vaccination have exalted in the prospect of exterminating the Small Pox from the face of the earth; while its opponents have framed their tales of horror, replete with stories of novel diseases and unheard-of plagues.... When...

Therapeutic choices in the locomotor management of the child with cerebral palsy--more luck than judgement?
October 1, 2001... In the past 15 years or so our understanding of many aspects of cerebral palsy has significantly broadened. Traditional concepts regarding aetiology have been radically challenged, and we now acknowledge that "birth asphyxia", once felt to be...

Case-control study of the health of those looked after by local authorities.(health care of children under authority care worse than those living at home)
October 1, 2001... Abstract Aims--To assess the health needs and provision of health care to school age children in local authority care. Methods--A total of 142 children aged 5 to 16 in local authority care, and 119 controls matched by age and sex were...

Should children with developmental and behavioural problems be routinely screened for lead?
October 1, 2001... Abstract Aim--To test the hypothesis that children with behavioural and/or developmental problems have significantly higher blood lead concentrations than the general childhood population. Methods--Blood samples were taken from 69...

How common is abuse in Greece? Studying cases with femoral fractures.(child abuse demographics)
October 1, 2001... Abstract Aims--To examine the extent of undiagnosed child abuse in Greece by studying young children with femoral fractures, which may be associated with abuse. Methods--Fifty seven consecutive cases of children under 6 years of age...

Solar disinfection of drinking water protects against cholera in children under 6 years of age.
October 1, 2001... Abstract Background and Aims--We have previously reported a reduction in risk of diarrhoeal disease in children who used solar disinfected drinking water. A cholera epidemic, occurring in an area of Kenya in which a controlled trial of...

Drug misusing parents: key points for health professionals.
October 1, 2001... Drug misuse is common, and users of illicit drugs tend to be young. Many have children. A serious drug misuse problem in the parents can be devastating for the lives of their children. [1] Addiction to opiates, most commonly heroin, is one of...

Who is failing abused and neglected children?
October 1, 2001... This is a response to an article by Nigel Speight and Jane Wynne, 'Is the Children Act failing severely abused and neglected children?', published in this journal in March 2000. [1] Overall, we consider the article to be polemical and...

Non-traumatic coma in children.
October 1, 2001... Many acutely ill children are a not fully conscious. Most make a full neurological recovery as the underlying cause is treated, but considerable skill is required to distinguish the group at high risk of further deterioration, potentially...

Fine needle aspiration biopsy of thyroid nodules.
October 1, 2001... Abstract Background--Fine needle aspiration biopsy (FNA) is a routine diagnostic technique for evaluating thyroid nodules. Many reports in adults consider that FNA is superior to thyroid ultrasonography (USG) and radionucide scanning (RS)....

Hypernatraemic dehydration and breast feeding: a population study.
October 1, 2001... Abstract As part of a population based regional review of all neonatal readmissions, the incidence of dehydration with hypernatraemia in exclusively breast fed infants was estimated. All readmissions to hospital in the first month of life...

Down's syndrome and acute lymphoblastic leukaemia: clinical features and response to treatment.
October 1, 2001... Abstract Aims--To examine the clinical and biological features of acute lymphoblastic leukaemia in children with Down's syndrome (DS), to compare their survival with other children, and to determine if entry to trials and survival has...

Severe upper airway obstruction caused by ulcerative laryngitis.
October 1, 2001... Abstract Aims--To present our experience of severe upper airway obstruction caused by ulcerative laryngitis in children. Methods--Retrospective case note review of 263 children with severe upper airway obstruction and a clinical...

Symptomatic adrenal insufficiency during inhaled corticosteroid treatment.
October 1, 2001... Abstract Symptomatic adrenal insufficiency, presenting as hypoglycaemia or poor weight gain, may occur on withdrawal of corticosteroid treatment but has not previously been reported during inhaled corticosteroid treatment. This case series...

Peripheral gangrene during infancy: a rare presentation of systemic lupus erythematosus.
October 1, 2001... Abstract An 11 month old boy presented with gangrene of the extremities. He was found to have positive nuclear antibodies and antibodies to double stranded DNA, and negative Ro and La antibodies. The infant was started on oral...

Growth study of cri du chat syndrome.
October 1, 2001... Abstract We compared the growth of children with cri du chat (5p-) syndrome with the 1990 UK growth curves. Most subjects had impaired growth, particularly of head circumference. The more emaciated the child the more pronounced the...

Successful treatment of carbohydrate deficient glycoprotein syndrome type 1b with oral mannose.
October 1, 2001... Abstract An Asian girl presented with failure to thrive, congenital hepatic fibrosis, protein losing enteropathy, and hypoglycaemia. Phosphomannose isomerase activity in skin fibroblasts was reduced. She is homozygous for a mutation,...

Diagnostic and therapeutic impact of whole body positron emission tomography using fluorine-18-fluoro-2-deoxy-D-glucose in children with chronic granulomatous disease.
October 1, 2001... Abstract Aims--To compare whole body positron emission tomography (PET) using fluorine-18-fluoro-2-deoxy-D-glucose (FDG) with computed tomography (CT) in detecting active infective foci in children with chronic granulomatous disease. ...

Effect of bacterial filters on spirometry measurements.(analysis of amount of difference in lung function measurements)
October 1, 2001... Abstract Lung function measurements with and without a disposable bacterial filter were compared in 60 children. Although statistically significant, the reduction of lung function measurements caused by using bacterial filters was small...

LETTERS TO THE EDITOR.(Rapid responses)(DMSAs after UTI--scan more children, not less)(Age specific aetiology of anaphylaxis)(Letter to the Editor)
October 1, 2001... Rapid responses If you have a burning desire to respond to a paper published in ADC or F&N, why not make use of our "rapid response" option? Log on to our website (www. archdischild.com), find the paper that interests you, click on...

Poverty and Child Health, 2d ed.(Review)
October 1, 2001... Poverty and child health. N Spencer. (Pp352, 2nd ed.) Radcliffe Medical Press. ISBN 1-85775-477-8. I noted contrasting newspaper headlines in the week I read this book (February 2001): "5m Britons living on the breadline" (referring to the...

Typhoid fever commonly affects young children.
October 1, 2001... Typhoid fever commonly affects young children in endemic areas and antibiotic resistance is increasing (in a large epidemic in Tajikistan in 1996-98 over 90% of the organisms were multidrug resistant and 82% were ciprofloxacin resistant). The...

Most common kind of psychiatric disorder to affect children.(are anxiety disorders)
October 1, 2001... Anxiety disorders are said to be the most common kind of psychiatric disorder to affect children but the best way of treating them is uncertain. In a placebo controlled trial at five US academic centres (New England Journal of Medicine...

A multicentre trial involving 12-33 month old inner city American children with moderate lead poisoning.
October 1, 2001... A multicentre trial involving 12-33 month old inner city American children with moderate lead poisoning (blood lead concentrations 1.0-2.1 [micro]mol/L (20-44 [micro]g/dl)) (New England Journal of Medicine 2001;344:1421-6) showed no difference...

Systemic cyclosporin is effective treatment for severe atopic dermatitis.
October 1, 2001... Systemic cyclosporin is effective treatment for severe atopic dermatitis but the drug does not penetrate the epidermis and is therefore ineffective when applied topically. Two drugs, ascomycin and tacrolimus, which have mechanisms of action...

In children with severe neurological impairment.(incidence of severe gastroesophageal reflux after fundoplication and gastrostomy)
October 1, 2001... In children with severe neurological impairment, severe gastro-aesophageal reflux may recur after fundoplication and gastrostomy. The operation of total oesophagogastric dissociation with Roux-en-Y oesophagojejunostomy and non-refluxing feeding...

Does a lot of lead in the air make people kill people?
October 1, 2001... Does a lot of lead in the air make people kill people? This strange proposition has received some support from an ecological study involving all 3111 contiguous counties in the USA (Archives of Pediatrics and Adolescent Medicine...

In Guinea-Bissau children under 3 years old with persistent diarrhoea.(treated with diet therapy gained more weight than control group)
October 1, 2001... In Guinea-Bissau (American Journal of Clinical Nutrition 2001;73:968-74) children under 3 years old with persistent (2 weeks or more) diarrhoea were randomly assigned to dietary management (a home made gruel containing millet, egg, banana,...

Paediatric dermatologists at seven US centres.(kwashiorkor diagnosis)
October 1, 2001... Paediatric dermatologists at seven US centres (Archives of Dermatology 2001;137:630-6) diagnosed kwashiorkor in 12 children aged 1-22 months over a period of 9 years. Nutritional ignorance, parentally suspected milk intolerance, and food...

In the Austrian State of Tyrol.(early detection of hearing impairment increased after universal newborn screening use)
October 1, 2001... In the Austrian State of Tyrol (International Journal of Pediatric Otorhinolarynology 2001;59:23-8) the introduction of universal newborn hearing screening resulted in a 40% increase in the number of children whose hearing impairment was...

A Case control study in Montreal.(children with siblings and those who attend day care before age 1 have a reduced risk for asthma at age 3-4)
October 1, 2001... A case control study in Montreal (American Journal of Epidemiology 2001;153:6538) has confirmed that having siblings and attending day care before the age of 1 year both reduce the risk of asthma at age 3-4 years. Breastfeeding had no effect,...

Mometasone furoate is a glucocorticoid with high local potency and low systemic availability.
October 1, 2001... Mometasone furoate is a glucocorticoid with high local potency and low systemic availability. A study of 733 patients (adults and children over 11 years old) at 60 centres in 20 countries (Annals of Allergy, Asthma, and Immunology...

Viral infection.(may increase heart transplant failure in children)
October 1, 2001... Viral infection, particularly with adenovirus, may increase the risk of transplant failure after heart transplantation in children. In the USA (New England Journal of Medicine 2001;344;1498-503) 149 children had 553 endomyocardial biopsy...

In Boston, Massaehusetts, six adults with severe haemophilia.(gene therapy for hemophilia)
October 1, 2001... In Boston, Massachusetts, six adults with severe haemophilia A were treated with gene therapy (New England Journal of Medicine 2001;344:1735-42). They were given back (by laparoscopic injection into the omentum) their own skin fibroblasts...