Neurology Alert articles from September 2002

Neurology Alert archives from September 2002

Will new approaches help to treat ALS? (Abstract & Commentary).
September 1, 2002... Source: Almer G, et al. Increased levels of the pro-inflammatory prostaglandin PGE2 in CSF from ALS patients. Neurology. 2002;58: 1277-1279. INFLAMMATORY MECHANISMS MAY PARTICIPATE IN THE PATHO-genesis of neurodegenerative diseases...

Editor's note.(Flint Beal is new co-editor of Neurology Alert)
September 1, 2002... In this issue of Neurology Alert, Flint Beal, MD, will join me as the co-editor Dr Beal is Professor and Chairman of the Department of Neurology at Cornell University Medical College. During my 20 years of editorship, the goal of Neurology...

Highlights from the 8th Annual International Alzheimer's Disease meeting. (Conference Coverage).
September 1, 2002... Source: Neurobiol Aging: 2002,23(1S):S1-$606. MORE THAN 2000 DEMENTIA-RELATED STUDIES were presented at the 8th International Conference on Alzheimer's Disease and Related Disorders (ICADRD), held in Stockholm, Sweden, July 20-25, 2002....

Structural neuropathology in preclinical Huntington's disease. (Abstract & Commentary).
September 1, 2002... Source: Thieben MJ, et al. The distribution of structural neuropathology in preclinical Huntington's disease. Brain. 2002;125:1815-1828. HUNTINGTON'S DISEASE (HD) IS AN AUTOSOMAL dominant neurodegerative disorder linked to an expanded CAG...

Hyperglycemia and the acute ischemic penumbra. (Abstracts & Commentary).
September 1, 2002... Sources: Parsons MW, et al. Acute hyperglycemia adversely affects stroke outcome: A magnetic resonance imaging and spectroscopic study. Ann Neural. 2002;52:20-28; Ginsberg MD. Hyperglycemia and stroke outcome: Vindication of the ischemic...

Neurology of celiac disease. (Abstract & Commentary).
September 1, 2002... Source: Tengah DS, et al. Neurological complications of celiac disease. Postgrad Med J. 2002;78:393-398. BEST RECOGNIZED AS A CHRONIC DIARRHEAL ILLNESS with bloating and progressive weight loss, celiac disease has a definite association...

Is normal pressure hydrocephalus a valid concept in 2002? (Abstract & Commentary).
September 1, 2002... Source: Bret P, et al. Is normal pressure hydrocephalus a valid concept in 2002? A reappraisal in five questions and proposal for a new designation of the syndrome as "chronic hydrocephalus." J Neurol Neurosurg Psychiatry. 2002; 73:9-12. ...

Ischemic white matter disease may predispose to intracerebral hemorrhage. (Abstract & Commentary).
September 1, 2002... Source: Smith EE, et al. Leukoaraiosis is associated with warfarin-related hemorrhage following ischemic stroke. Neurology. 2002;59:193-197. I SCHEMIC WHITE MATTER DISEASE, ALSO REFERRED TO as leukoaraiosis, is found commonly and often...

Efficacy of angiotensin II receptor antagonists in preventing headache. (Clinical Briefs in Primary Care[TM]).(Brief Article)
September 1, 2002... Source: Etminan M, et al. Am J Med. 2002;112:642-646. HEADACHE IS AMONG THE MOST COM-manly reported events in placebo-controlled trials of pharmaceutical agents, usually occurring in both the recipients of active drug and placebo. It has...

Effect of lower doses of HRT on bone in early postmenopausal women. (Clinical Briefs in Primary Cary[TM]).(hormone replacement therapy)(Brief Article)
September 1, 2002... Source: Lindsay R, et al. JAMA. 2002;287:2668-2676. In ADDITION TO RELIEF OF VASOMOTOR symptoms, postmenopausal hormone replacement therapy (HRT) has been shown to improve bone mineral density (BMD). Traditionally, 0.625 mg of conjugated...

Pulse pressure and cardiovascular disease-related mortality. (Clinical Briefs in Primary Cary[TM]).(Brief Article)
September 1, 2002... Source: Domanski M, et al. JAMA. 2002;287:2677-2683. THE POPULATION OF MEN SCREENED for participation in the Multiple Risk Factor Intervention Trial (MRFIT) has provided a large population (n = 342,815) from which to derive important...

Comparative efficacy of insect repellents against mosquito bites. (Clinical Briefs in Primary Care).(Brief Article)
September 1, 2002... Source: Fradin MS, Day JF. N Engl J Med. 2002;347:13-18. MOSQUITOES ARE TYPICALLY VIEWED as nuisance pests, though in the United States they are responsible for a variety of types of encephalitis, and globally, for malaria. Since mosquito...

Reduction in self-monitoring of blood glucose in type 2 diabetes results in cost savings and no change in glycemic control. (Clinical Briefs in Primary Care).(Brief Article)
September 1, 2002... Source: Meier JL, et al. Am J Manag Care. 2002;8:557-565. NATIONALLY, IN THE US VETERANS Administration (VA) population, diabetes (DM) is responsible for 24% of pharmacy costs. The Northern California Health Care System VA (data source for...

Vasectomy and risk of prostate cancer. (Clinical Briefs in Primary Care).(Brief Article)
September 1, 2002... Source: Cox B, et al JAMA 2002, 287:3110-3115. BEGINNING ABOUT 1990, CASE-CONtrol data suggested that vasectomy (VAS) was associated with an increased risk of prostate cancer (PCA). Subsequently (1993), 2 large cohort studies indicated a...

WHI trial arm stopped due to increase in breast cancer. (Pharmacology Watch).
September 1, 2002... Overall health risks exceeded benefits from use of combined estrogen plus progestin for an average 5.2-year follow-up among healthy postmenopausal US women" is the stunning conclusion from the Women's Health Initiative published in the July 17...