Neurology Alert articles from April 2002

Neurology Alert archives from April 2002

Two forms of unilateral consistent headache and its sources.
April 1, 2002... ABSTRACTS & COMMENTARY Sources: Bahra A, et al. Neurology. 2002;38:354-361; Pringsheim T. Can J Neurol Sci. 2002;29:33-40; Pareja JA, et al. Cephalalgia. 2001;21:940-946. THESE 3 REPORTS INDIVIDUALLY DISCUSS PARTIAL REVIEWS OF classic...

Viral encephalitis: a deadly differential diagnosis.
April 1, 2002... ABSTRACTS & COMMENTARY Source: Whitley RJ, Gnann JW. Lancet. 2002;359:507-512. WHITLEY AND GNANN REVIEWED THE RECENT LIT-erature on viral encephalitis and present an up-to-date summary of the pathogenesis, clinical syndromes,...

Visual hallucinations in Lewy body disease.
April 1, 2002... ABSTRACT & COMMENTARY Source: Harding AJ, et al. Brain. 2002;125:391-403. THE PATHOLOGIC HALLMARK OF PARKINSON'S DISease (PD) is the accumulation of Lewy bodies within the substantia nigra. Improvements in immunohistochemistry in the...

The current status of status epilepticus.
April 1, 2002... ABSTRACT & COMMENTARY Sources: Mayer SA, et al. Arch Neurol. 2002;59(2):205-210; Claassen J, et al. Neurology. 2002;58(1):139-142; Logroscino G, et al. Neurology. 2002;58(4):537-541. MAYER AND COLLEAGUES ANALYZED 83 EPISODES OF status...

Sleep apnea syndrome: Insights into neurocardiogenic interactions.
April 1, 2002... ABSTRACTS & COMMENTARY Sources: Garrigue S, et al. N Engl J Med. 2002;346:404-412; Gottlieb DJ. N Engl J Med. 2002;346:444-445. SLEEP APNEA SYNDROME (SAS) IS A DISORDER WITH wide ranging physiological and social consequences. In the...

Myasthenia and non-AchR autoantibodies.
April 1, 2002... ABSTRACT & COMMENTARY Source: Romi F, et al. Eur JNeurol. 2002;9:55-61. AMONG 43 PATIENTS WITH ONSET OF GENERALIZED Amyasthenia gravis (MG) older than age 50, 21 were thymectomized and 22 nonthymectomized. Serum antimuscle antibodies...

Complex regional pain syndrome.(reflex sympathetic dystrophy)
April 1, 2002... ABSTRACT & COMMENTARY Source: Rho RH, et al. Mayo Clin Proc. 2002;77:174-180. REFLEX SYMPATHETIC DYSTROPHY (RSD) AS A SYNdrome is so broad that some feel it has lost its use as a clinical diagnosis. Neither reflex arcs nor the...

Late Breakers.(new column)
April 1, 2002... Neurology Alert is pleased to introduce our new column "Late Breakers." In an effort to stay up to date, Neurology Alert will be including short reviews of current therapeutics in both early and pivotal stage development. Different from our...

GlaxoSmithKline withdrawals Lymerix: Company 'cuts losses' on controversial Lyme disease vaccine.
April 1, 2002... Citing poor sales, GlaxoSmithKline has announced that it is withdrawing Lymerix, the Lyme disease vaccine, from the market. The vaccine was the first, and only, Lyme disease vaccine on the market. Lymerix generated $40 million in sales in 1999,...

Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. (Clinical Briefs in Primary Care).
April 1, 2002... Source: Knowler WC, et al. N Engl J Med. 2002;346:393-403. PERSONS WHO ARE AT HIGH RISK FOR developing type 2 diabetes (DM2) include persons with elevated fasting and 2-hour postprandial glucose levels (ie, above normal but not qualifying...

Eradication of Helicobacter pylori and risk of peptic ulcers in patients starting long-term treatment with NSAIDs. (Clinical Briefs in Primary Care).
April 1, 2002... Source: Chan FK, et al. Lancet. 2002;359:9-13. THERE ARE A VARIETY OF PATIENT groups that require long-term therapy with NSAIDs, such as arthritis sufferers. That traditional NSAIDs can produce an increased risk of significant GI bleeding...

Physiotherapy for patients with mobility problems more than 1 year after stroke: a randomized controlled trial. (Clinical Briefs in Primary Care).
April 1, 2002... Source: Green J, et al. Lancet. 2002;359:199-203. FOR STROKE VICTIMS WHO SUFFER A subsequent decrement in mobility (ie, falls, difficulty in walking, problems getting out of a chair), consequences of such disability are potentially...

EBV antibodies and risk of MS. (Clinical Briefs in Primary Care).(Epstein-Barr virus; multiple sclerosis)(Brief Article)
April 1, 2002... Source: Ascherio A, et al. JAMA. 2001;286:3083-3088. CURRENT THEORIES DOMINANTLY support an autoimmune etiologic basis for multiple sclerosis (MS). An epidemiologic phenomenon peculiar to Epstein-Barr virus (EBV) is its pattern of...

Coronary magnetic resonance angiography for the detection of coronary stenoses. (Clinical Briefs in Primary Care).
April 1, 2002... Source: Kim WY, et al. N Engl J Med. 2001;345:1863-1869. CORONARY ANGIOGRAPHY (GANG) 15 the current gold standard for diagnosis of clinically significant coronary artery disease (CAD), which is generally designated as greater than 50%...

Vitamin A intake and hip fractures among postmenopausal women. (Clinical Briefs in Primary Care).
April 1, 2002... Source: Feskanich D, et al. JAMA. 2002;287:47-54. VITAMIN A AND ITS ANALOGUES (VitA) have been shown to produce changes in bone metabolism and structure that would logically increase risk of fracture. In animals, retinoic acid decreases...