Journal of Neurology, Neurosurgery and Psychiatry articles from February 2001

Journal of Neurology, Neurosurgery and Psychiatry archives from February 2001

New drug treatments for epilepsy.(Statistical Data Included)
February 1, 2001... After the introduction of valproate in 1973, excluding benzodiazepines, there was a 19 year gap before the introduction of vigabatrin, the first in a series of new antiepileptic drugs to be developed and licensed. At the time of writing...

Building an evidence base for multiple sclerosis management: support for physiotherapy.(Brief Article)
February 1, 2001... The recent debate in the United Kingdom over whether or not 3-interferon and glatiramer acetate should be prescribed on the National Health Service for people with multiple sclerosis has focused the attention of the media, health services, and...

Comparative neuropsychology of Lewy body and Alzheimer's dementia.(dementia with Lewy Bodies compared to Alzheimer's)(Brief Article)
February 1, 2001... The occurrence of Lewy bodies has a prevalence rate of 2%-9% in elderly people [1] and dementia with Lewy bodies (DLB) accounts for 12%-27% of cases previously diagnosed as dementia of the Alzheimer type (DAT). [2,3] The core features of DLB...

Semantic memory is impaired in both dementia with Lewy bodies and dementia of Alzheimer's type: a comparative neuropsychological study and literature review.
February 1, 2001... Abstract Objective--To test the hypothesis that semantic impairment is present in both patients with dementia with Lewy bodies (DLB) and those with dementia of Alzheimer's type (DAT). Methods--A comprehensive battery of...

Perception, attention, and working memory are disproportionately impaired in dementia with Lewy bodies compared with Alzheimer's disease.(Statistical Data Included)
February 1, 2001... Abstract Objective--To test the hypotheses that visuoperceptual and attentional ability are disproportionately impaired in patients having dementia with Lewy Bodies (DLB) compared with Alzheimer's disease (AD). Methods--A comprehensive...

Temporal lobe rating scale: application to Alzheimer's disease and frontotemporal dementia.(Statistical Data Included)
February 1, 2001... Abstract Objectives--Temporal lobe atrophy as assessed by MRI can be measured in several ways. Volumetric measurements are quantitative but very time consuming and require extensive training to perform, so are not easily transferable to...

Controlled randomised crossover trial of the effects of physiotherapy on mobility in chronic multiple sclerosis.(Statistical Data Included)
February 1, 2001... Abstract Objectives--To determine whether physiotherapy can improve mobility in chronic multiple sclerosis and whether there is a difference between treatment at home and as a hospital outpatient? Methods--A randomised controlled...

Impact of depressed mood on neuropsychological status in temporal lobe epilepsy.(Statistical Data Included)
February 1, 2001... Abstract Objectives--Depression is a common psychiatric complication of temporal lobe epilepsy. This study examined the effect of depressed mood on neuropsychological performance among patients with chronic temporal lobe epilepsy. ...

Fear as the main feature of epileptic seizures.(fearful behavior is often a type of partial epileptic seizure and is often misdiagnosed as a panic attack)(Statistical Data Included)
February 1, 2001... Abstract Objectives--There are circumstances in which partial seizures may be misdiagnosed as acute psychiatric disturbances. In particular, when fear is the prominent feature the patient may be considered for years as having panic...

Decreased sleep quality and increased sleep related movements in patients with Tourette's syndrome.(Statistical Data Included)
February 1, 2001... Abstract Objective--Sleep quality and movement patterns across sleep stages in patients with Tourette's syndrome were examined to determine the influence of syndrome severity on sleep quality and the differential effect of sleep stages on...

Preliminary experience of the estimation of cerebral perfusion pressure using transcranial Doppler ultrasonography.(Statistical Data Included)
February 1, 2001... Abstract Objective--The direct calculation of cerebral perfusion pressure (CPP) as the difference between mean arterial pressure and intracranial pressure (ICP) produces a number which does not always adequately describe conditions for...

Detection of subarachnoid haemorrhage with magnetic resonance imaging.(evaluation of various forms of magnetic resonance imaging)(Statistical Data Included)
February 1, 2001... Abstract Objectives--To measure the sensitivity and specificity of five MRI sequences to subarachnoid haemorrhage. Methods--Forty one patients presenting with histories suspicious of subarachnoid haemorrhage (SAH) were investigated...

Long term outcome in Lambert-Eaton myasthenic syndrome without lung cancer.(Statistical Data Included)
February 1, 2001... Abstract Objectives--To determine the prognosis in patients with Lambert-Eaton myasthenic syndrome (LEMS) without small cell lung cancer (SCLC), and to analyse longitudinal clinical, electrophysiological, and immunological data on each...

Olfactory function in patients with olfactory groove meningioma.(Statistical Data Included)
February 1, 2001... Abstract Objectives--Olfactory meningiomas are rare benign tumours and represent about 12% of all basal meningiomas. Anosmia is thought to be among the first symptoms, even though patients often present with headaches or visual problems....

Paraneoplastic brain stem encephalitis in a woman with anti-Ma2 antibody.
February 1, 2001... Abstract A woman developed brain stem encephalopathy in association with serum anti-Ma2 antibodies and left upper lobe lung mass. T2 weighted MRI of the brain showed abnormalities involving the pons, left middle and superior cerebellar...

Hiemicraniectomy in elderly patients with space occupying media infarction: improved survival but poor functional outcome.(Statistical Data Included)
February 1, 2001... Abstract Objective--To assess the survival rate and functional outcome in elderly patients with space occupying supratentorial infarction who underwent hemicraniectomy compared with those who received medical treatment alone. ...

Platelet monoamine oxidase B and plasma [beta]-phenylethylamine in Parkinson's disease.
February 1, 2001... Abstract Objective--To evaluate the correlation between changes in platelet monoamine oxidase type B (MAO-B) activity and plasma [beta]-phenylethylamine (PEA) concentrations in patients with Parkinson's disease and controls. ...

Mild recurrent neuropathy in CMT1B with a novel nonsense mutation in the extracellular domain of the MPZ gene.(Charcot-Marie-Tooth disease type1B)(Statistical Data Included)
February 1, 2001... Abstract Clinical, electrophysiological, and neuropathological features are reported associated with a novel heterozygote point mutation in the extracellular domain of the MPZ gene, where a transversion at codon 71 in exon 3 leads to a...

Unusual spontaneous and training induced visual field recovery in a patient with a gunshot lesion.
February 1, 2001... Abstract Over a period of more than 3 years, changes in visual and neuropsychological functions were examined in a patient with a visual field defect caused by a cerebral gunshot lesion. Initially, the patient had been completely blind,...

Clinical factors of drug resistance in juvenile myoclonic epilepsy.(Statistical Data Included)
February 1, 2001... Abstract Juvenile myoclonic epilepsy is a comparatively benign form of idiopathic generalised epilepsy. Little is known about the prevalence of difficult to treat or drug resistant patients. Among 155 consecutive patients with newly...

Significance of atypical presentation of symptomatic SUNCT: a case report.
February 1, 2001... Abstract A patient with a SUNCT-like syndrome caused by severe basilar impression in association with osteogenesis imperfecta is described. Initially symptoms of both the first and second branch of the trigeminal nerve were prominent, on...

Analysis of stimuli triggering attacks of paroxysmal dystonia induced by exertion.(Statistical Data Included)
February 1, 2001... Abstract In a patient with a familial form of paroxysmal exertion induced dyskinesia (PED), the efficacy of different stimuli and manoeuvres in triggering dystonic attacks in the arm was studied. As a new approach, transcranial magnetic...

Complete bilateral horizontal gaze paralysis disclosing multiple sclerosis.
February 1, 2001... Abstract Two women presented with bilateral internuclear ophthalmoplegia evolving in a few days to complete bilateral horizontal gaze paralysis. Convergence and vertical eye movements were normal. Cerebral MRI showed a few small white...

Charles Robert Richet (1850-1935).
February 1, 2001... Although he had a preference for literature the French Physiologist Charles Richet studied medicine to please his father, a distinguished surgeon. As a medical student in Paris Charles Richet became interested in hypnosis. This led to the...

Primary diffuse leptomeningeal gliomatosis predominantly affecting the spinal cord: case report and review of the literature.
February 1, 2001... Abstract Primary leptomeningeal gliomatosis is a rare, fatal neoplastic syndrome. A 71 year old man is reported on, who after a 2 month history of back stiffness, epigastric pain, and weight loss developed visual blurring. Cranial CT and...

Diagnosis of a multifocal B cell lymphoma with preceding demyelinating central nervous system lesions by single voxel proton MR spectroscopy.
February 1, 2001... Abstract Single voxel proton magnetic resonance spectroscopy (MRS) provides a rapid non-invasive fingerprint of tissue chemistry. A case history is presented in which a B cell lymphoma with antecedent demyelinating lesions of the CNS was...

The simple solution to a complex case.
February 1, 2001... During Spring 1999 this 41 year old woman experienced paraesthesia and difficulties with moving her right arm for about 30 minutes, which improved spontaneously. In August 99 the patient noted a bluish disseminated discoloration over the...

LETTERS TO THE EDITOR.
February 1, 2001... The cingulate hidden hand Studies on primates, and increasing evidences in humans, support the notion that the anterior cingulate cortex, which subserves various executive functions, is involved in the preparation and execution of motor...

Relation between Glasgow outcome score extended (GOSE) and the EQ-5D health status questionnaire after head injury.
February 1, 2001... In this Journal Wilson et al investigated aspects of the validity of the Glasgow outcome score (GOS) and the extended form (GOSE), particularly the relation between the GOS and subjective reports of health status. [1] A potentially useful...

An Atlas of Peripheral Nerve Pathology.(Review)
February 1, 2001... An Atlas of Peripheral Nerve Pathology. By ROSALIND KING. (PP 217, [pound]125). Published by Arnold, London, 1999. ISBN 0-340-586664. Whether it is because peripheral nerve has a limited repertoire of responses to pathological insults or...

Infectious diseases of the nervous system.(Review)
February 1, 2001... Infectious diseases of the nervous system. Edited by LARRY E DAVIS and PETER G E KENNEDY. (Pp 544, [pound]65.00.) Published by Butterworth Heinemann, Oxford, 2000. ISBN 0-7506-4213-0 Infections of the nervous system often present to and are...

Proceedings of the Association of British Neurologists and Societe Suisse de Neurologie Joint meeting, The Commonwealth Institute, London, 20-22 September 2000.(Statistical Data Included)
February 1, 2001... Analysis of pooled individual patient data from randomised controlled trials of carotid endarterectomy for symptomatic Stenosis PM ROTHWELL, SA GUTNIKOV, MR MAYBERG, CP WARLOW, HJM BARNElT Radcliffe Infirmary, Oxford, UK Carotid...