Gut articles from March 2001, page 6

Gut archives from March 2001

THROMBIN IN GASTRIC VARICES.(Abstract)
March 1, 2001... Background: The management of gastric variceal haemorrhage remains a clinical challenge. We carried out a retrospective study to investigate our experience in the use of thrombin for treating gastric variceal bleeding. Patients and...

PROSPECTIVE STUDY OF LIVER DYSFUNCTION IN PREGNANCY IN SOUTH WALES.(Abstract)
March 1, 2001... Background and aims: Liver disease is uncommon in pregnancy but has serious consequences. Its frequency varies according to country and ethnic origin and is not documented in Wales. We have prospectively determined incidence, causes and...

HOW WELL TOLERATED IS DAY CASE LIVER BIOPSY?(Abstract)
March 1, 2001... It is recognised that day case liver biopsy is under-utilised in UK hospitals. Little is known about post discharge events in patients having this procedure. Patients/methods: All patients satisfying BSG criteria for day case liver...

POPULATION-BASED EPIDEMIOLOGY OF LIVER ENZYME TESTS: EVALUATING NORMAL AND ABNORMAL TESTS IN TAYSIDE, 1991-97.(Abstract)
March 1, 2001... Liver function tests are routinely performed in primary and secondary care. Studies have quantified the incidence of liver enzyme abnormalities, but neglect subjects that subsequently retest normal or do not retest at all. The aim of this...

THE EFFECT ON TOXICITY ON REDUCING THE SIZE OF AVAILABLE PARACETAMOL PACK SIZES.(Abstract)
March 1, 2001... C.L. Sheen [1] J.F. Dillon [2] D.N. Bateman [3] K. Simpson [4] T.M. MacDonald [5] Introduction: Paracetamol overdose is a common cause of hepatotoxicity and death, and the incidence has been increasing. As a means of...

A NOVEL [[CO.sup.13].sub.2] BREATH TEST FOR THE NON-INVASIVE ASSESSMENT OF SYNTHETIC LIVER FUNCTION IN-VIVO.(Abstract)
March 1, 2001... W. Meier-Augenstein [1] H.F. Kemp [1] J.F. Dillon E. Henry (1.) School of Life Sciences, University of Dundee, Dundee DDI 4HN; (2.) Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY UK ...

TISSUE TRANSGLUTAMINASE ANTIBODIES AND COELIAC DISEASE IN PATIENTS WITH PRIMARY BILIARY CIRRHOSIS AND AUTOIMMUNE CHOLANGITIS.(Abstract)
March 1, 2001... E. Kouroumalis [1] K. Chatzikostas [1] M. Roussomoustakaki [1] D. Drygiannakis [2] M. Niniraki [3] M. Koulentaki [1] M. Tzardi [4] (1.) Depts of Gastroenerology, (3.) Inmmunology, (4.) Pathology, University...

THE INFLUENCE OF PRE-ADMISSION DIET UPON LIVER FUNCTION TESTS OF PATIENTS WITH ACUTE ALCOHOLIC HEPATITIS.(Abstract)
March 1, 2001... Diet has been implicated in the development of alcoholic liver disease. Epidemiological studies suggest a diet high in saturated fatty acid (SFA) is associated with a lower mortality from alcoholic cirrhosis, and polyunsaturated fatty acid...

ALCOHOL CONSUMPTION PATTERNS IN HEAVY DRINKERS WITH AND WITHOUT ALCOHOLIC LIVER DISEASE (ALD).(Abstract)
March 1, 2001... R.J. Peck [1] Gastroenterology and Liver Unit and (1.) Dept of Radiology, Royal Hallamshire Hospital Sheffield, UK Background: The risk of ALD increases with increasing alcohol consumption; it is unclear whether the risk is also...

EVIDENCE A REDUCTION IN HEPATIC PERFUSION DURING EARLY ABSTINENCE IN ACUTE ALCOHOLIC HEPATITIS.(Abstract)
March 1, 2001... Background: It has been noted that patients with acute alcoholic hepatitis (AAH) often worsen several days after admission to hospital and abrupt cessation of alcohol. The reason for this deterioration is unknown. Aim: We aimed to assess...

STUDY OF ACUTE LIVER FAILURE IN SCOTLAND.(Abstract)
March 1, 2001... Introduction: Acute liver failure (ALP) is a devastating condition which although rare retains a high mortality. New information on its incidence and outcome are important in planning for this condition. Aims: (1) To accurately describe...

HEALTH RESOURCE USE AND COSTS ASSOCIATED WITH VIRAL HEPATITIS.(Abstract)
March 1, 2001... The true size of the problem of chronic viral hepatitis is becoming apparent, the real costs in population terms have only so far been modelled. This study examined the heath resource use and costs associated with chronic viral hepatitis from...

DISTINCT FUNCTIONAL PATTERNS OF HBV-SPECIFIC CD8+ CELL RESPONSE IN HEPATITIS B VIRUS INFECTION.(Abstract)
March 1, 2001... S. Reignat [1] D. Brown, G. Ogg [2] M. Lascar [1] P. Malacarne [1] R Williams [1] A. Bertoletti [1] M. Lascar [1] R Williams [1] A. Bertoletti [1] Introduction: The range of manifestations of HBV...

PRECORE HBV MUTANT INFECTION IS MORE COMMON THAN EXPECTED AMONG HBV CARRIERS IN SCOTLAND.(Abstract)
March 1, 2001... Background: Chronic Hepatitis B is uncommon and HBV precore mutant infection is presumed to be low in Scotland. Aims: 1) Compare HBeAg(+) with AntiHBe(+) carriers 2) Analyse virological characteristics of AntiHBe(+) carriers Method:...

NEURAL NETWORKING IN HEPATITIS C PATIENTS TO PREDICT KNODELL SCORES.(Abstract)
March 1, 2001... J. Tharakan [1] D. Koutsomanis [2]. (1.) Dept of Medicine, Victoria Hospital, Blackpool, UK; (2.) Dept of Gastroentrology, Hospital Fecamp, France Hepatitis C is a relatively common disease and prone to chronicity. Liver...

ACUTE AND CHRONIC EFFECTS OF INTERFERON ALPHA THERAPY ON MOOD AND THE HYPOTHALAMIC PITUITARY ADRENAL (HPA) AXIS IN PATIENTS WITH CHRONIC HEPATITIS C.(Abstract)
March 1, 2001... Backround: Fatigue and depression are common sequelae of interferon alpha therapy. The pathogensis of this is unclear. Interferon at low doses { = 5 million units } is known to stimulate the HPA axis. Dysregulation of this axis occurs in upto...

VALIDATION OF THE REVISED INTERNATIONAL AUTOIMMUNE HEPATITIS GROUP (IAHG) SCORING SYSTEM: EXPERIENCE IN THE NORTH OF ENGLAND.(Abstract)
March 1, 2001... A.M. Baragiotta [1] W.L. Craig [1] O.F.W. James [1] M.F. Bassendine [1] (1.) Centre for Liver Research, The Medical School, University of Newcastle NE2 4HH, UK Introduction: Autoimmune hepatitis (AIH) is a chronic...

INTEGRIN RECEPTOR EXPRESSION CHANGES IN DISEASED HEPATIC STELLATE CELLS.(Abstract)
March 1, 2001... The extracellular matrix (ECM) is now recognised as exerting a powerful influence on cell phenotype. Hepatic stellate cells are the principal effectors of liver fibrosis. If isolated and maintained in vitro on a normal basement membrane-like...

THE PREVENTION AND TREATMENT OF MURINE COLITIS USING GENE THERAPY WITH ADENOVIRAL VECTORS ENCODING INTERLEUKIN-10.(Abstract)
March 1, 2001... Background: Interleukin-10 knockout (IL-10 -1-) mice spontaneously develop Th1 T cell mediated colitis with many similarities to Crohn's disease. Daily injections of IL-10 are able to prevent disease onset but do not induce remission in...

ACID 1 STUDY: RESULTS OF A RANDOMISED TRIAL OF H. PYLORI ERADICATION IN PATIENTS ON MAINTENANCE ACID SUPPRESSION IN THE COMMUNITY.(Abstract)
March 1, 2001... Objective: The assessment of community intervention in dyspepsia (ACID1) study investigates the effect of H pylori (Hp) eradication in a large community based dyspeptic population irrespective of underlying diagnosis. Patients/methods:...

TGF-[alpha] INDUECES A [beta]-CATENIN/TCF MEDIATED TRANSCRIPTION EVENT IN BARRETT'S OESOPHAGUS.(Abstract)
March 1, 2001... In Barrett's Oesophagus one of the earliest identified events is the up-regulation of the EGF-receptor, and its associated ligand TGF-[alpha]. Previous reports have identified a number of alternations in the expression and localisation of...

SWITCHING ON SWALLOWING, SWITCHING ON THE BRAIN--A NEW APPROACH FOR THE TREATMENT OF DYSPHAGIA.(Abstract)
March 1, 2001... C. Fraser [1] M. Power [1] S. Hamdy [1] D. Hobday [1] I. Hollander [1] A. Hobson [1] P. Tyrell [1] S. Williams [1] J. Rothwell [2] D.G. Thompson [1] (1.) University of Manchester, Manchester; ...

ADMISSION BLOOD LACTATE IS PREDICTIVE OF OUTCOME IN PARACETAMOL INDUCED ACUTE LIVER FAILURE.(Abstract)
March 1, 2001... Background: The Kings College (KCH) criteria select patients with paracetamol induced acute liver failure (ALF) for transplantation (OLT) but have limited sensitivity and may identify patients too late for successful OLT. In a large cohort of...

THE PREVALENCE OF COELIAC DISEASE IN PATIENTS FULFILLING THE ROME 2 CRITERIA FOR IRRITABLE BOWEL SYNDROME: A CASE CONTROL STUDY.(Abstract)
March 1, 2001... Background: European studies suggest that up to 20% of the population suffer with irritable bowel syndrome (IBS). The diagnosis is made by fulfilling symptom based criteria and the exclusion of organic pathology. Coeliac disease (CD) is...