OBGYN & Reproduction Week articles from December 2004

OBGYN & Reproduction Week archives from December 2004

Cyclosporine A exposure in utero linked to adulthood kidney problems, high BP.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- They are calling for a long-term clinical survey of children born to women who received cyclosporin A therapy during their pregnancy. "The number of pregnant women who receive cyclosporin A (CsA)...

Long-term use of depo-provera contraceptive injection may cause osteoporosis.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration (FDA) announced on November 17, 2004, that a "black box" warning will be added to the labeling of Depo-Provera Contraceptive Injection, indicating that prolonged...

High stress doubles risk of painful periods.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- High levels of stress double the risk of painful periods, according to a new study. Primary dysmenorrhea, otherwise known as painful periods without any organic cause, is one of the most common...

U.S. sees steep rise in elective cesarean deliveries.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- The United States has seen a steep rise in cesarean deliveries in women with no reported medical risk, data show. Researchers analyzed information on 4 million births per year between 1991 and...

Recent immigration, lack of partner support, preeclampsia are risk factors.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Recent immigration, lack of partner support, and pregnancy-induced hypertension are significant factors in predicting whether women will experience depressive symptoms soon after giving birth, says a...

Corrections being made to Louisiana abortion brochure.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Less than a week after learning that a state brochure incorrectly said abortions could increase the risk of breast cancer, health officials had a new version up on the Internet. It will take a bit...

Prenatal alcohol exposure has effects far beyond fetal alcohol syndrome.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Numerous studies have documented intelligence quotient (IQ) deficits in children with fetal alcohol syndrome (FAS). Little research, however, has found IQ deficits in children with alcohol-related...

Minor behavioral deficits seen in rats exposed prenatally to synthetic estrogen.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Rats exposed in utero to synthetic estrogen - specifically, 17alpha-ethinylestradiol - exhibit minor deficits in exploratory behavior. According to recent research published in the journal...

Retinoic acid exposure in utero alters cranial neural crest gene expression.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Retinoic acid exposure in utero alters cranial neural crest gene expression, researchers report. "Although retinoic acid (RA), the active form of vitamin A, is required for normal embryonic growth...

Poland: Multiple embryo implantation blamed for high neonatal mortality in ART.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Specialists at Poland's University of Medical Science blame the country's lack of regulation of multiple embryo implantation for the high rate of neonatal mortality in pregnancies achieved via assisted...

Estrogen-associated COX-2 pathways may explain heart disease protection.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Heart disease is less pronounced in women than in men as humans age, but this difference narrows after menopause. Some studies have shown that estrogen slows heart disease in mouse models, but the...

Folic-acid supplementation can prevent 70% of spina bifida cases.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Folic-acid supplementation can prevent 70% of spina bifida cases, researchers report. A "seminar" in the November 20, 2004, issue of the Lancet discussed the causes, symptoms, and treatments...

Depo-Provera adds black box warning about bone density loss.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Depo-Provera, an injectable contraceptive, will come with a special warning that links prolonged use of the drug with bone density loss, the U.S. government said November 17, 2004. The U.S. Food...

Chemotherapies have varied effects on menopausal symptoms of cancer patients.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Oncologists in Belgium have studied "the changes in frequency and severity of menopausal symptoms in patients receiving tamoxifen or aromatase inhibitors and identified factors influencing these...

Prochieve maker provides Q3 report, updates PROTERM study.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Columbia Laboratories, Inc., (CBRX) announced financial results for the third quarter and 9 months ended September 30, 2004. Highlights of the quarter included: 1) Net sales of $5.1 million, a...

BRCA1 missense variant thwarts transcriptional activity.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- One of two BRCA1 missense variants identified by researchers in the U.S. has deleterious effects on gene transcription. "Many families with multiple cases of ovarian cancer, breast cancer, or both...

Clinical studies needed to evaluate role of BRCA1 in chemotherapy response.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Prospective clinical studies are needed to evaluate the role of BRCA1 in response to taxane-based chemotherapy, researchers say. Loss of BRCA1 function is associated with sensitivity to...

SOCS1 and 2 genes suppress growth of ovarian and breast carcinoma cells.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Suppressor of cytokine signaling genes 1 and 2 suppress the growth of ovarian and breast carcinoma cells, researchers in Australia have shown. "Suppressor of cytokine signaling (SOCS) proteins have...

Chemoradiation with gemcitabine an alternative for patients with renal failure.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Chemoradiation with gemcitabine is an alternative for patients with renal failure when cisplatin-based therapy is contraindicated, study results indicate. L. Cetina and colleagues, National...

Clinical trial investigates food supplement's preventive effects.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Did your grandmother always tell you to eat your greens? It appears that she may have known something scientists are only now discovering. When the substances produced in cruciferous vegetables...

HPV 16 infection a risk factor for disease progression in younger women.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Infection with human papillomavirus 16 infection is a significant risk factor for cervical cancer progression in younger women, study data indicate. "Human papillomaviruses (HPV), particularly type...

Small cell neuroendocrine carcinomas of the uterine cervix characterized.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Pathologists with Yamagata University, Japan, recently characterized small cell neuroendocrine carcinomas of the uterine cervix. G.M. Ishida and colleagues stated, "Small cell carcinomas of the...

Study says Ireland's high death rate is due to lack of screening program.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Death rates from cervical cancer in the Republic of Ireland exceed those in all other regions in Britain and Northern Ireland because there is no national screening program, claims a new report. ...

Study: Shorter, more aggressive treatments better control disease.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Women receiving care at small, local radiation therapy facilities are less likely to receive shorter, more aggressive treatments for their cervical cancer, according to a study by M.D. Anderson Cancer...

Clinical testing of transdermal contraceptive spray begins.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- The Population Council and Acrux Limited (ASX: ACR), an Australian pharmaceutical company that specializes in administering drugs through the skin, announced on November 15, 2004, the start of the...

Evaluate C. pneumoniae IgG antibodies in cases of coronary artery disease.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Researchers have investigated the relationship between dyslipidemia, C-reactive protein and serological evidence of Chlamydia pneumoniae in Turkish patients with coronary artery diseases. ...

Intrauterine infection can cause increased Th1 cytokine levels in fetal brain.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Intrauterine infection can cause increased Th1 cytokine levels in the fetal brain, which in turn causes inflammation that can damage developing white matter, according to a study from the United States....

Computed tomography can identify HSV-related hepatitis in pregnant women.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Computed tomography can identify HSV-related hepatitis in pregnant women. According to published research from the United States, "fulminant hepatitis due to herpes simplex virus (HSV) is rare in...

Women often neglect health when prevention is most important.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Feeling fine? No troublesome health problems? Another year to skip an annual doctor visit? According to women's health specialists at Mayo Clinic, many women in midlife forgo a yearly physical...

Case of vertically transmitted HSV-2 infection resembled calcified myocarditis.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Obstetrician/gynecologists in Charlotte, North Carolina, have reported a case of congenital herpes simplex virus infection that appeared sonographically to be calcified myocarditis. "Congenital...

Cervical cancer's image as a niche market hinders drug development.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Decision Resources, Inc., has found that, because of slow-to-change treatment strategies and a low burden of disease in developed countries, interest in trials of novel agents for invasive cervical...

Recent advances in endometriosis highlighted.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- A recent article reviewed "recent advances in our understanding of endometriosis with special reference to its pathogenesis, recent molecular studies, and relationship to neoplasia." According to...

Updated government study finds mercury levels in women, children 'not a concern'.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- The U.S. Tuna Foundation (USTF) stated that by finding that mercury levels in women and young children are very low and "not of concern," a new study from the U.S. Centers for Disease Control and...

Female sexual function improves with treatment of male partner.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Female sexual function improves after effective treatment of erectile dysfunction (ED) in male partners. Researchers in Turkey conducted a study "to compare sexual functioning between women with...

Cytyc announces investment in endometriosis-focused company.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Cytyc Corp. (CYTC) announced that it has made an equity investment in Valeo Medical, Inc., a privately held company focused on developing a serum-based test for endometriosis. Terms of the...

Essure maker reports on Q3; year-to-date net sales up 47%.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Conceptus, Inc., (CPTS), developer of the nonincisional permanent birth control procedure Essure, reported financial results for the 3 and 9 months ended September 30, 2004. Consistent with...

Transdermal drug delivery pharmaceutical reports third quarter EPS of $0.11.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Noven Pharmaceuticals, Inc. (NOVN) announced financial results for the quarter and 9 months ended September 30, 2004, provided an update on its business, and confirmed prior financial guidance for...

Fungi isolated from pregnant diabetic women have lower phosphatase activity.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Fungi isolated from pregnant diabetic women were found in a recent study to have lower alkaline and acid phosphatase activity. D. Nowakowska, at the Polish Mothers Memorial Hospital, and colleagues...

No link found between gene polymorphism and GDM in a Taiwanese population.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Although the Trp64Arg polymorphism of beta(3)-adrenergic receptor (ADRB3) has been reported to be associated with insulin resistance and gestational diabetes mellitus (GDM), no such link was found in a...

Hyaluronan synthase 1 expression associates with ovarian cancer progression.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Hyaluronan synthase 1 expression associates with ovarian cancer progression. According to a study from Japan, "to determine if the immunohistochemical expression of hyaluronan synthase (HAS)...

Sindbis viral vectors detect and suppress advanced ovarian cancer xenografts.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Sindbis viral vectors detect and suppress advanced ovarian cancer xenografts. "We studied the therapeutic value of Sindbis vectors for advanced metastatic ovarian cancer by using two highly...

Oxidative metabolism of estrogen modulates ERT/HRT response in older women.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- The oxidative metabolism of estrogen modulates postmenopausal women's response to hormone therapy, researchers report. In earlier work, R.C. Armamento-Villareal at Barnes Jewish Hospital in St....

Factors associated with HPV-16 seropersistence in Costa Rican women identified.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Epidemiologists in the United States identified factors associated with seroconversion and seropersistence of human papillomavirus 16 (HPV-16) in a large group of women in Costa Rica. "Serologic...

Immersion Medical introduces educational Hysteroscopic Myomectomy CD.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Immersion Corporation (IMMR) announced that its wholly owned subsidiary, Immersion Medical, Inc., has introduced the first product of its Educational Suite on compact disk - Hysteroscopic Myomectomy CD....

Oligosaccharides may influence lymphocyte maturation in breastfed newborns.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Oligosaccharides - particularly acidic oligosaccharides - may influence lymphocyte maturation in breastfed newborns, according to research from Austria. "Human milk contains large amounts of free...

TLRs differentially expressed in distinct regions of female reproductive tract.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- According to published research from the United States, "Toll-like receptor (TLR) signal transduction is a central component of the innate immune response to pathogenic challenge. "Although recent...

Study investigated methods of euthanasia for mouse fetuses and neonates.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Euthanasia of mouse fetuses and neonates was the focus of recent research. According to a study from the United States, "We sought to determine whether any of the common methods of euthanasia for...

Skilled attendants vital to saving lives of mothers and newborns.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- The number of skilled attendants in developing countries needs to be increased by at least 333,000 if the international community is to meet the Millennium Development Goal (MDG) of reducing maternal...

Inorganic mercury accumulated in the brains of offspring.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- A recent report described mercury and trace element distribution in organic tissues and regional brain of fetal rats after in utero and weaning exposure to low dose of inorganic mercury. According...

Healthcare corporation agrees to sell California hospital to CHA Medical Group.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Tenet Healthcare Corporation (THC) announced that a company subsidiary has entered into a definitive agreement to sell 434-bed Hollywood Presbyterian Medical Center in Los Angeles, California, to the...

Hormone therapy improves risk factors in postmenopausal women.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Estrogen replacement therapy improves various risk factors that predispose postmenopausal to metabolic syndrome, study data indicate. J.S. Green at Texas A&M University and colleagues studied "the...

Ovariectomy-associated memory deficits in mice improve by estropausal age.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- According to a study from Finland, "Spatial memory deficits occur earlier in female than male rodents as the animals age, and the cessation of estrous cycle has been suggested to play a role in this...

California's selects mass spectrometry system for expanded newborn screening.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- PerkinElmer, Inc., (NYSE: PKI), the world's leading provider of neonatal screening systems, and a leading provider of drug discovery, life science research, and analytical solutions, recently announced...

Certain intrauterine infections may cause trophoblast apoptosis through TLRs.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- According to published research from the United States, "Intrauterine infections have been associated with pregnancy complications that are also linked with increased trophoblast apoptosis. ...

Folic acid supplements during pregnancy reduce whole blood coagulability.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Folic acid supplements during pregnancy reduce whole blood coagulability, hematologists report. "Thromboembolic disease remains the leading cause of maternal death in the U.K. Recent literature has...

Leptin signals probably not a key factor in preeclampsia pathogenesis.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Researchers in China say leptin signals probably aren't a key factor in the pathogenesis of preeclampsia. They "investigated the expression profile of placental leptin and leptin receptor isoforms...

Mechanisms of hypoxia-induced fetal growth restriction studied.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- According to published research from the United States, "Molecular mechanisms underlying fetal growth restriction due to placental insufficiency and in utero hypoxia are not well understood. "In...

Night work linked to increased risk of late pregnancy loss.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Women who work fixed night-time hours during pregnancy, but not those who work rotating shifts, are more likely to suffer fetal loss, according to a study from Denmark. The findings were published...

Premies' infections increase risk for mental, physical problems.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Infections shortly after birth are a surprisingly significant cause of cerebral palsy and other brain-development disorders in the tiniest premature babies, a study found. It is well known that...

Survey results prompt improved obstetric care in Mali.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Survey results indicating an unmet need for major obstetric surgery among women in Mali prompted measures to improve obstetric care in this population. "A national retrospective survey on the unmet...

U.S. FDA adds new warnings to mifepristone labeling.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration (FDA) announced important new safety changes to the Danco Laboratories, LLC's labeling of mifepristone (trade name: Mifeprex, also known as RU-486). Mifeprex...

Plasma from pregnant rats has antitumoral activity.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Scientists in Spain have found that plasma from pregnant rats exhibits antitumoral activity. N. Carbo, University of Barcelona, and colleagues reported, "Plasma from 12-day pregnant rats showed a...

Oral contraceptives improve knee-joint stability.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Not only is pregnancy avoided by taking oral contraception, so is knee injury, according to researchers at McGill University and the McGill University Health Center (MUHC). These new findings,...

Beneficial effects of alendronate or exercise lost when therapy is stopped.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- The benefits of alendronate and/or exercise therapy in preventing bone loss in menopausal women don't last for long once therapy is discontinued, study data reveal. Researchers in Finland assessed...

Body composition changes with age have gender-specific impacts on BMD.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Changes in body composition that come with age have gender-specific impacts on bone mineral density, epidemiologists in South Korea say. "Body weight, smoking, alcohol, physical activity, and diet...

Daily and intermittent oral ibandronate normalizes bone turnover.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Daily and intermittent use of oral ibandronate normalizes bone turnover and significantly reduces osteoporotic fracture risk in postmenopausal women, researchers in France report. "Increasing...

Glabridin acts similarly to estradiol-17beta and may modulate bone health.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- According to a study from Israel, "Data from both in vivo and in vitro experiments demonstrated that glabridin and glabrene are similar to estradiol-17beta in their stimulation of the specific activity...

Hyperhomocysteinemia due to low folate associated with low BMD in Iranian study.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Study results show hyperhomocysteinemia due to folate deficiency is associated with low bone mineral density in Iranian women. The findings don't apply, however, to hyperhomocysteinemia resulting...

IL-6 promoter polymorphism associated with bone quality in postmenopausal women.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- The presence and position of one allele in an interleukin-6 promoter polymorphism is associated with previous fracture in postmenopausal women, researchers in Sweden report. "Interleukin 6 (IL-6)...

Low calcium intake, inactivity, older age are risk factors in Thai women.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Independent risk factors for osteoporosis that researchers have identified in postmenopausal Thai women are the same as for women in other parts of the world. C. Pongchaiyakul at Australia's Garvan...

NPY signal gene polymorphism may benefit postmenopausal femoral neck BMD.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- A leucine7-to-proline7 polymorphism in the neuropeptide Y signal gene may be associated with higher femoral neck bone mineral density in postmenopausal women, according to a study from Finland. ...

Postmenopausal ER loss diminishes estrogen's anti-nociceptive action.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Results of a study in rats suggest that estrogen-receptor loss that occurs postmenopausally may account for the long-term ineffectiveness of estrogen to ameliorate pain associated with osteoporosis. ...

Study: Elderly women with distal radial fracture have low hip, lumbar spine BMD.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Of 94 postmenopausal women with distal radial fracture, 85% had low bone mineral density of the lumbar spine and hip, researchers evaluating the women found. "The incidence of distal radial...

42-bp deletion within ERCC1 5' UTR can affect therapeutic cisplatin response.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- A 42 base-pair deletion within the 5'-UTR of the ERCC1 gene can affect ovarian cancer response to cisplatin therapy. T.Y. Li, West Virginia University, and colleagues, said, "Our previous studies...

Focal adhesion kinase may be important therapeutic target.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Focal adhesion kinase may be important therapeutic target in ovarian cancer, M.D. Anderson Cancer Center gynecologic oncologists say. According to A.K. Sood and colleagues, "Focal adhesion kinase...

Gene expression profiling aids in ovarian cancer prognosis.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- The identification of a gene expression profile using microarray technology may help clinicians better determine the prognosis of patients with advanced stage ovarian cancer and may eventually help...

Hypermethylation is a common, relatively early event in ovarian tumorigenesis.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Oncologists with the Fox Chase Cancer Center, Philadelphia, have determined that hypermethylation is a common, relatively early event in ovarian tumorigenesis that can be detected in serum DNA of...

Loss of beta-catenin associated with poor survival.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Loss of beta-catenin is associated with poor survival in women with ovarian cancer, report oncologists in Portugal. "The catenins (alpha-, beta-, and gamma-) are cytoplasmic proteins that bind to...

Study: Urinary incontinence, abdominal pain are key early warning signs.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Results from an Olmsted Medical Center and Mayo Clinic study analyzing symptoms recorded in the medical records of ovarian cancer patients suggest ovarian cancer, long considered asymptomatic until...

Trial compares docetaxel to paclitaxel for first-line treatment of cancer.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- The combination of docetaxel and carboplatin for first-line treatment of ovarian cancer appears to result in similar rates of survival compared with the current standard, paclitaxel and carboplatin,...

p53 deficiency alone doesn't prompt ovarian epithelial tumorigenesis in mice.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Researchers report that p53 deficiency alone doesn't prompt ovarian epithelial tumorigenesis in mice and so "other genetic lesions are likely required to develop mouse models of human ovarian cancer."...

SFRP1 gene is inactivated by promoter methylation in human ovarian cancers.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- A study from Japan has determined that the SFRP1 gene is inactivated by promoter methylation in human ovarian cancers. According to T. Takada and colleagues, National Cancer Center, Tokyo, "The...

Transdermal fentanyl compared to IV PCA morphine after gynecologic surgery.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Researchers have reported that IONSYS, a novel patient-controlled, transdermal, analgesic system that delivers fentanyl through the skin, may be comparable to intravenous patient-controlled analgesia...

Breastfeeding best for preventing misaligned baby teeth.
December 6, 2004... 2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Babies who are given pacifiers and bottle-fed are twice as likely to have misaligned milk or "baby" teeth as babies who are breastfed, suggests new research. Milk teeth will be replaced by...