OBGYN & Reproduction Week articles from April 2003

OBGYN & Reproduction Week archives from April 2003

Prenatal exposure to methamphetamine restricts infant growth.
April 7, 2003... 2003 APR 7 - (NewsRx.com & NewsRx.net) -- Prenatal exposure to methamphetamine restricts infant growth. "To determine fetal growth and the incidence of withdrawal symptoms in term infants exposed to methamphetamine in utero, we...

High cortisol levels during pregnancy linked to hypertension risk for offspring.
April 7, 2003... 2003 APR 7 - (NewsRx.com & NewsRx.net) -- New results, presented at the British Endocrine Societies 2003 meeting, from a study by a group at the Western General Hospital in Edinburgh may explain why fetal exposure to high levels of the stress...

In vitro fertilization may be linked to bladder defects.
April 7, 2003... 2003 APR 7 - (NewsRx.com & NewsRx.net) -- Researchers from the Johns Hopkins Children's Center report that a group of rare urological defects, including bladder development outside the body, may be more common in children conceived through in...

Immune cells participate in uterine angiogenesis during pregnancy.
April 7, 2003... 2003 APR 7 - (NewsRx.com & NewsRx.net) -- Immune cells participate in uterine angiogenesis during pregnancy. "Granulated metrial gland (GMG) cells are a major immune cell population in the murine pregnant uterus, and contribute to the...

Smoking damages the placenta and reduces fetal growth.
April 7, 2003... 2003 APR 7 - (NewsRx.com & NewsRx.net) -- Dr. Peter Hindmarsh (University College, London), at the British Endocrine Societies 2003 meeting, revealed new evidence that smoking when pregnant causes damage to the placenta and reduced birth...

Invention designed to help arthritis sufferers, expectant mothers.
April 7, 2003... 2003 APR 7 - (NewsRx.com & NewsRx.net) -- Warm water is soothing to arthritis and pregnancy; however, unless the lower back is supported, invisible tensions in one's lumbar region will diminish the healing benefits. With the help of a...

Embryo implantation is successful despite an extensive endometrial defect.
April 7, 2003... 2003 APR 7 - (NewsRx.com & NewsRx.net) -- Embryo implantation is successful despite an extensive endometrial defect. "Successful implantation occurred after embryo transfer in the presence of an extensive endometrial defect after...

Study begins of technique to increase chances of pregnancy in IVF.
April 7, 2003... 2003 APR 7 - (NewsRx.com & NewsRx.net) -- Reproductive Medicine Associates of New Jersey (RMA NJ), a fertility center, is beginning a clinical study to test a new technique that may improve pregnancy rates in women undergoing in vitro...

The HLA-G gene responsible is repressed postnatally by DNA methylation.
April 7, 2003... 2003 APR 7 - (NewsRx.com & NewsRx.net) -- The HLA-G gene responsible is repressed postnatally by DNA methylation. According to recent research from France, "The HLA-G molecule plays an important role in immune tolerance, protecting the...

Management of arrhythmias, cardiomyopathy and aortic stenosis described.
April 7, 2003... 2003 APR 7 - (NewsRx.com & NewsRx.net) -- Management of arrhythmias, cardiomyopathy and aortic stenosis described. "The U.K. registry of high-risk obstetric anesthesia was set up in late 1996 to collect reports of high-risk pregnancy, pool...

Treatment of mild vaginal infection during pregnancy could reduce miscarriage.
April 7, 2003... 2003 APR 7 - (NewsRx.com & NewsRx.net) -- Authors of a U.K. study conclude that the treatment of mild vaginal infection during pregnancy could reduce the risk of late miscarriage and premature birth. Mild bacterial infection in the vagina -...

Vascular remodeling in the placenta is different in high-altitude pregnancies.
April 7, 2003... 2003 APR 7 - (NewsRx.com & NewsRx.net) -- Vascular remodeling in the placenta is different in high-altitude pregnancies. "Patterns of fetoplacental angiogenesis and villous growth vary in pregnancies complicated by different forms of fetal...

High levels of lead in the placenta don't correlate with smaller infant size.
April 7, 2003... 2003 APR 7 - (NewsRx.com & NewsRx.net) -- High levels of lead in the placenta don't correlate with smaller infant size. According to recent research from Spain, "prenatal exposure to lead produces toxic effects in the human fetus, including...

Physiological apoptotic agents differentially affect human amnion cells.
April 14, 2003... 2003 APR 14 - (NewsRx.com & NewsRx.net) -- Human amnion cell types respond differently to physiologic apoptotic agents, and the epithelial cells are far more sensitive to lactosylceramide than mesenchymal cells. According to recent...

Hypoxia-inducible factors perform several roles in the pregnant uterus.
April 14, 2003... 2003 APR 14 - (NewsRx.com & NewsRx.net) -- Hypoxia-inducible factors perform several roles in the pregnant uterus. According to a study from the United States, "increased uterine vascular permeability and angiogenesis are hallmarks of...

Pain killers don't negatively affect misoprostol during pregnancy termination.
April 14, 2003... 2003 APR 14 - (NewsRx.com & NewsRx.net) -- Pain killers don't negatively affect misoprostol during pregnancy termination. "This double-blind randomized control study was conducted to evaluate whether a nonsteroidal anti-inflammatory drug...

Overall diet quality may compound the risk for neural tube defects.
April 14, 2003... 2003 APR 14 - (NewsRx.com & NewsRx.net) -- Overall diet quality may compound the risk for neural tube defects. "Many studies have examined the impact of single nutrients on neural tube defect (NTD) risk, particularly folate. The impact of...

Exogenous estrogen has role in etiology of chronic angioneurotic edema.
April 14, 2003... 2003 APR 14 - (NewsRx.com & NewsRx.net) -- Exogenous estrogen has iatrogenic role in etiology of chronic angioneurotic edema. According to recent research from France, "Although frequently reported as an etiology for chronic angioneurotic...

Beta2GP1 may be adjunct to aCL, LA testing in patients with significant history.
April 14, 2003... 2003 APR 14 - (NewsRx.com & NewsRx.net) -- Beta2GP1 may be adjunct to aCL and LA testing in patients with significant obstetric history while investigating for antiphospholipid syndrome. "Beta 2 glycoprotein 1 (beta2GP1) is a...

Women and their partners consider a new contraception system acceptable.
April 14, 2003... 2003 APR 14 - (NewsRx.com & NewsRx.net) -- Women and their partners consider a new contraception system acceptable. "This study investigated the long-term acceptability of a levonorgestrel-releasing intrauterine system (LNG-IUS) in 165...

More study is needed of women who are considered candidates for cerclage.
April 14, 2003... 2003 APR 14 - (NewsRx.com & NewsRx.net) -- More study is needed of women who are considered candidates for cerclage. "Uterine contractions, decidual activation, and cervical competence comprise the fundamental components in contemporary...

ETS2 overexpression is linked to p53 dependent apoptosis.
April 14, 2003... 2003 APR 14 - (NewsRx.com & NewsRx.net) -- Chromosome 21 abnormality involved in Down syndrome, creates overexpression of ETS2 which induces p53 dependent apoptosis; this may be involved in the formation of syndrome symptoms and pathology. ...

Retroviruses are feasible vectors for gene delivery to primitive sperm cells.
April 14, 2003... 2003 APR 14 - (NewsRx.com & NewsRx.net) -- Retroviruses are feasible vectors for gene delivery to primitive sperm cells According to a study from the United States, "spermatogonia represent a new route to transgenesis in mice and...

Ob-Gyns praise West Virginia's new law on medical liability reform.
April 14, 2003... 2003 APR 14 - (NewsRx.com & NewsRx.net) -- The American College of Obstetricians and Gynecologists (ACOG) applauded West Virginia lawmakers for their recent enactment of HB 2122, legislation to address the state's chronic medical liability...

NovaSure procedure may render hysterectomy obsolete.
April 14, 2003... 2003 APR 14 - (NewsRx.com & NewsRx.net) -- Every 10 minutes, four potentially unnecessary hysterectomies are performed in the United States for the treatment of excessive menstrual bleeding, also known as menorrhagia. This debilitating...

Elevated antiphospholipid antibodies may increase thromboembolism risk.
April 14, 2003... 2003 APR 14 - (NewsRx.com & NewsRx.net) -- Elevated antiphospholipid antibodies may increase thromboembolism risk. "The role of thrombophilia in the elevated risk of thromboembolism during oral contraceptive use has been established. We...

Estrogen and androgen receptors mediate 17 alpha-MT and HSP effects on uterus.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- According to George Washington University researchers, "Testosterone and the synthetic androgen, 17alpha-methyltestosterone (MT), have been shown to increase uterine weights and alter uterine...

Overexpression and secretion of angiogenin may play a role in IUGR.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Researchers in Singapore suggest that the significantly higher levels of angiogenin they observed in intrauterine growth retardation placenta "may provide a molecular mechanism for the abnormal...

Attitude, intention key to exercise in pregnant women.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Attitude and intention are the two most important factors in pregnant women's decisions about exercising, according to exercise psychologists at Penn State and the University of Florida. "A...

Association of maternal caffeine consumption with decrements in fetal growth.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Pregnant coffee-lovers can still enjoy their java in moderation, study results suggest, without worry about harmful effects of caffeine on their babies. Since effects of mothers' caffeine intake...

Pulmonary diffusing capacity in pregnancy is affected by residential altitude.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- The altitude where a pregnant woman spends the most time - presumably her residence - affects pulmonary diffusing capacity, study results show. This has implications especially for pregnant women...

Physicians key to successful recruitment of women in mental health trials.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- The most successful strategy for recruiting women to participate in clinical trials addressing prevention and treatment of postpartum depression is referral by an obstetrician or other healthcare...

Serum IgG homeostasis in humans requires binding for longevity.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- IgG affinity is involved in the mechanism of serum homeostasis, as nonbinding IgG go down a lysosomal pathway. "IgG is the most abundant serum antibody and is an essential component of the humoral...

Study finds no association between in vitro fertilization and cancer development.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Study finds no association between in vitro fertilization and cancer development. "The objective of this paper is to assess whether ovarian hyperstimulation and in vitro fertilization (IVF) are...

Germline BACH1 mutations do not appear linked to breast and ovarian cancer.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Mutation in BACH1, a helicase, suggested to be a marker for breast and ovarian cancer, was not found to be prevalent in Finnish patients. According to a study from Finland, "Recently, BACH1, a...

HPV16 integrates preferentially at common fragile sites.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- HPV16 tends to prefer integration at common fragile sites, and loss of function at these sites may contribute to cervical cancer development. According to a study from the United States, "The...

Melatonin modulates the action of near infrared radiation on cell adhesion.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Melatonin modulates the action of near infrared radiation on cell adhesion in cervical cancer. According to published research from Russia, "The adhesion of human cervical cancer (HeLa) cells to a...

New diagnostic tests perform no better than conventional tests.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- New cervical smear tests are unreliable and should not replace conventional tests, according to a new study. Researchers in France studied 828 women referred to hospital because abnormalities had...

Obstetric product licensed out for marketing.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Cytokine PharmaSciences, Inc., (CPSI) has signed an exclusive license with Integrity Pharmaceutical Corporation for U.S. rights to market CPSI's second-generation cervical ripening product. ...

Polymorphic membrane protein H evolves in parallel with 3 disease-causing groups.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Polymorphic membrane protein H in Chlamydia trachomatis evolves in parallel with 3 disease-causing groups. According to a study from the United States, "Chlamydia trachomatis is a human pathogen...

Three-plane color Doppler examination is sufficient to detect most fetal CHD.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Three-plane color Doppler examination is sufficient detect most common fetal congenital heart defects(CHD). "Routine use of color Doppler during every fetal cardiac examination remains...

Factors linked to women discontinuing the Pill identified in rural Bangladesh.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- A number of factors have been identified that are associated with women ages 15 to 49 years living in rural areas of Bangladesh discontinuing use of oral contraceptives. "Oral contraceptives (OCs)...

Prenatal diagnosis of NCVM possible with current ultrasound equipment.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Prenatal diagnosis of noncompaction of the ventricular myocardium (NCVM) is made possible by current ultrasonographic equipment. According to published research from England, "Isolated...

Two human leukocyte antigen class I antigens are more frequent.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Two specific HLA class I antigens were found in higher amounts in endometriosis than in normal endometrium, but the rest were the same. According to published research from Japan, "An increasing...

Researchers develop a model of precancerous cervical squamous epithelium.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Researchers develop a model of precancerous cervical squamous epithelium. According to a study from England, "Electrical impedance spectroscopy is a technique that has been investigated as a...

Most GI surgery during pregnancy can be performed with minimal risk.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Most GI surgery during pregnancy can be performed with minimal risk. According to recent research published in the journal Gastroenterology Clinics of North America, "During pregnancy,...

Assessing quality of life can better address patients' concerns.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Assessing quality of life can better address patients' concerns. According to recent research published in the International Journal of Gynecological Cancer, "Quality of life is generally...

Exclusive rights obtained to HIV microbicide candidate.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Biosyn, Inc., announced that the company has acquired exclusive, worldwide rights from the U.S. National Institutes of Health (NIH) for the development and commercialization of the novel protein,...

High-Risk HPV DNA test approved by FDA.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Digene Corporation (DIGE) announced that the U.S. Food and Drug Administration (FDA) has approved Digene's Pre-Market Approval Supplement (PMAS) application for its hc2 High-Risk (HR) HPV DNA Test for...

Hemodialysis or hemofiltration to remove drug should be performed if available.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Hemodialysis or hemofiltration to remove lisinopril from bloodstream in pregnancy should be performed if available. "In general, angiotensin converting enzyme (ACE) inhibitors should be...

Copaxone shows no increased risk in pregnancy.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Women who took Copaxone (glatiramer acetate injection) during part of their pregnancies demonstrated no more risk than the general population of pregnancy outcomes, according to an abstract presented...

Ovulation and amount of ovulations in the age range of the 20s affect risk.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Ovarian cancer is found to be associated with the number of lifetime ovulations and ovulations during the twenties. "Incessant ovulation is thought to be one of the primary causes of epithelial...

Sardines offer Omega-3s for healthy fetal development.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- "Brain food" is more than just an expression when it comes to fish. From Oregon to Denmark, researchers have found that consuming fish during pregnancy and lactation reduces the risk of having a low...

Women at higher risk of later blood clots.
April 28, 2003... 2003 APR 28 - (NewsRx.com & NewsRx.net) -- Women with pre-eclampsia have a small but significantly higher risk of subsequent blood clotting (venous thromboembolism) compared with women diagnosed as having other common obstetrical diseases,...