Science Letter articles from October 2004

Science Letter archives from October 2004

Neural models are better than statistical models in measuring pig farm odor.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Neural network models perform better than statistical models in measuring pig farm odor because the statistical models are not able to consider the measurement location. "Pork farm odor has become...

Microscopy method enables dye-free observation of lone DNA molecules.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Differential interference contrast microscopy enables dye-free study of individual DNA molecules. In a study from the United States, "[d]irect observation of single native DNA molecules in a...

Extraction method to measure halogenated compounds in breast milk developed.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Scientists have developed a semiautomated high-throughput extraction and cleanup method for the measurement of polybrominated diphenyl ethers and polybrominated and polychlorinated biphenyls in breast...

Sensitive immunoassay for urinary permethrin developed.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Scientists have developed a sensitive immunoassay for the detection of permethrin in urine. "Permethrin is the most popular synthetic pyrethroid insecticide in agriculture and public health. For...

Tetrahydronaphthyl thioureas - potent appetite suppressants - synthesized.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Scientists have synthesized tetrahydronaphthyl thioureas, which are potent appetite suppressants. "A series of thiourea derivatives of 1-aminotetrahydronaphthalene and...

Nickel may affect structure and function of river biofilm communities.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Study finds that significant interactions occur between nickel (Ni), oxygen, and nutrients and that Ni at 0.5 mg liter[superscript]-1 may have significant affects on river microbial community. ...

11.5% of Biodyne acquired by technology company.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- QuantumBit Induction Technology Inc. (OTC:QBIT) has acquired 11.5% of Biodyne Inc. Biodyne Inc. is a Houston-based, privately held, biomedical development firm, and has engaged Biodyne in the...

Atomoxetine is novel treatment for attention deficit-hyperactivity disorder.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Atomoxetine is a novel treatment for attention deficit-hyperactivity disorder. "Atomoxetine is the first nonstimulant drug approved by the United States Food and Drug Administration (FDA) for the...

DataLex ADHD Indicator Report assessment tool introduced.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- The DataLex ADHD Indicator Report from Lexicor, the first biological assessment tool for ADHD, was introduced in Denver, Colorado. The DataLex ADHD Indicator Report uses brainwave data collected...

FDA approves Methylin Chewable Tablets, Methylin Oral Solution for ADHD.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Alliant Pharmaceuticals, Inc., announced U.S. Food and Drug Administration (FDA) approval of Methylin Chewable Tablets and Methylin Oral Solution for the treatment of ADHD. The two products are the...

AIDS progression linked to Fok-I polymorphism of VDR gene.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- An association exists between AIDS disease progression rates and the Fok-I polymorphism of the VDR gene in a cohort of HIV-1 seropositive patients. "In addition to its role in mineral metabolism,...

Memory CD4+ T cell responses in HIV not restored by antiretroviral therapy.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Central memory CD4+ T cell responses in chronic HIV infection are not restored by antiretroviral therapy. "A strong CD4+ T cell response has been correlated with better control of HIV infection....

Gag CTL-positive vaccinees recipients do not have anti-gag p17 response.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Gag CTL-positive, HIV-uninfected vaccine recipients expressing the HLA-A*0201 allele did not exhibit immunodominant anti-gag p17 (SL9) responses. According to recent research published in the...

HIV vaccine combination safe and immunogenic in HIV-negative adults.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- An HIV subtype B and E prime-boost vaccine combination was safe and immunogenic in HIV-negative Thai adults. "ALVAC-HIV (vCP1521) and AIDSVAX B/E were evaluated in a phase 1/2 trial of human...

Heat shock protein mediates cross-presentation of exogenous HIV antigen.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Heat shock protein mediates cross-presentation of exogenous HIV antigen on HLA class I and class II. According to a study from the United States, "Strong CD4+ and CD8+ T cell responses are...

Immune responses to hemagglutinin/SHIV-like particle vaccine reported.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Scientists report Th cell-independent immune responses to a chimeric hemagglutinin/simian human immunodeficiency virus-like particle vaccine. "CD4+ Th cells are believed to be essential for the...

Immunization with Listeria controls virus load after FIV challenge.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Oral immunization with recombinant Listeria monocytogenes controls virus load after vaginal challenge with feline immunodeficiency virus. "Recombinant Listeria monocytogenes has many attractive...

Methods to monitor oligomeric state of HIV vaccine antigen evaluated.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Researchers have evaluated on-line high-performance size-exclusion chromatography, differential refractometry, and multi-angle laser light scattering analysis for the monitoring of the oligomeric state...

Papillomavirus-HIV-1 gp41 virus-like particles induce HIV antibodies.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Oral immunization with bovine papillomavirus-HIV-1 gp41 chimeric virus-like particles induced mucosal and systemic neutralizing antibodies against human immunodeficiency virus type 1 (HIV-1). ...

Plasmacytoid dendritic cell activation augments SIV-specific T cells.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- CpG-C immunostimulatory oligodeoxyribonucleotide activation of plasmacytoid dendritic cells in rhesus macaques augments the activation of IFN-gamma-secreting simian immunodeficiency virus-specific T...

Recruiting London gay men into HIV vaccine trial is feasible.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Recruiting London gay men into an HIV vaccine trial is feasible. "This paper describes a study among HIV-negative gay men in London to examine willingness to volunteer for an HIV vaccine trial....

Screening for HIV-specific T-cell responses recommended.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Researchers recommend screening for HIV-specific T-cell responses using overlapping 15-mer peptide pools or optimized epitopes. "The IFN-gamma enzyme-linked immunospot (ELISpot) assay is often used...

Chromosomal translocations involving 6p22 breakpoint identified.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Novel chromosomal translocations in acute myeloid leukemia (AML) have been identified and characterized. "The detection of chromosomal aberrations is essential for the diagnosis and therapy" of...

Nicotine patches enhance effects of alcohol.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Transdermal nicotine patches enhance the effects of alcoholic beverages. "Nicotine and alcohol are often consumed together and smokers are more likely than non-smokers to drink alcohol," scientists...

DNA binding to viral enzyme may serve as new target for antiviral drugs.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Scientists at the U.S. Department of Energy's Brookhaven National Laboratory and the Albert Einstein College of Medicine have produced the first molecular-scale images of DNA binding to an adenovirus...

Paper describes new treatment for prevention of postsurgical adhesions.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- ARC Pharmaceuticals, Inc., announced that Dr. Johanne Cashman, director of preclinical research, published a paper entitled "Camptothecin-loaded Films for the Prevention of Postsurgical Adhesions" in...

Prevention programs need to address black female teens' wish to be pregnant.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Health behavior specialists say that programs aimed at preventing pregnancy and sexually transmitted diseases among African American teen girls need to take into account these adolescents' level of...

Study looks at family predictors of girls' sex-typed activities.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Free time activities of children and adolescents are important because they provide a forum for learning new skills and set the stage for identity development, researchers say. To better understand...

Calbindin-D-28K protects renal tubular cells from cyclosporine toxicity.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Calbindin-D-28K protects renal tubular cells from cyclosporine toxicity. According to a study from the United States, "cyclosporine A (CsA) is known to have direct toxicity to renal tubular cells....

Sevoflurane exposure is associated with a case of infant hepatitis.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Sevoflurane exposure is associated with a case of infant hepatitis. According to a report from Germany, "an 11-month-old child with primary hyperoxaluria was scheduled for a nephroureteromia...

Social and environmental factors play important role in how people age.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Why do some older people experience a rapid decline in their physical and functional health while some of their peers remain healthy and active? While genes and overall physical health are important,...

Monsanto enters collaboration to develop nematode-resistant soybeans.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Monsanto Co. (MOD) and Divergence, Inc., announced a collaborative relationship to develop nematode-resistant soybeans. The targeted pest, soybean cyst nematode, attacks roots of soybean during the...

Study says air worse in smoky bars than on truck-choked roads.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- If you're wondering whether a smoky bar or a city street filled with diesel truck fumes is more harmful to your health, you might want to skip your next happy hour. Smoky bars and casinos have up...

Sweet tooth, behavioral problems tied to alcoholism.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Men who have a sweet tooth and who have trouble controlling their behavior are more prone to alcoholism, and these factors combined were better predictors of the disease than any single individual...

Youth drinking trends stabilize, consumption remains high.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Although the prevalence of underage drinking has decreased since its peak in the late 1970s, drinking by youth has stabilized over the past decade at disturbingly high levels. The findings, part of...

Food Allergy Buddy dining card launched.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Philip Lempert, known by both consumers and the food industry as the "Supermarket Guru" and an expert analyst on consumer, marketing and food safety trends, announced the launch of the Food Allergy...

Drug in phase 2 clinical trial for patients suffering from peanut allergy.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Tanox, Inc. (TNOX) announced that the first patient has been enrolled in a phase 2 clinical trial evaluating the safety and efficacy of Xolair (omalizumab) in patients suffering from allergy (immediate...

DNA vaccine reverses allergic airway inflammation and eosinophilia.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Reversal of established CD4+ type 2 T helper-mediated allergic airway inflammation and eosinophilia by therapeutic treatment with DNA vaccines limits progression towards chronic inflammation and...

Mom's atopic disease modifies effects of prenatal risk factors on exhaled NO.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- According to a study from Switzerland, maternal atopic disease modifies the effects of prenatal risk factors on exhaled nitric oxide in infants. U. Frey and colleagues, University Hospital of Bern,...

Side effects greater with aqueous than depot therapy for bee venom allergy.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Early local side effects occur at higher frequency with aqueous than with depot immunotherapy for Hymenoptera venom allergy. "Venom immunotherapy has proven a very effective method for the...

Age-related myelin breakdown may be regionally heterogenous.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Study suggests that differences in myelin properties make later-myelinating regions more susceptible to myelin breakdown. According to published research from the United States, "Human and nonhuman...

Colostrinin found to be potential major advance in Alzheimer disease treatment.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- In vivo study in chicks shows that ReGen's Colostrinin reduces memory impairment induced by the toxic protein involved in Alzheimer disease. An in vivo study showing that pretreatment with...

Cyclooxygenase-3 expression is ancillary to COX-mediated neuropathogenesis.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Cyclooxygenase-3 expression is ancillary to COX-mediated neuropathogenesis. According to published research from the United States, "the cyclooxygenase (COX) superfamily of prostaglandin synthase...

Immunoglobulins might be promising treatment for AD.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Intravenous immunoglobulin might offer a promising treatment for Alzheimer disease, suggests preliminary research. Deposits of amyloid protein, which progressively damage brain tissue, are a...

Mild AD leads to errors on driving test.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- People with mild Alzheimer disease make more mistakes on a driving test than older people with no cognitive problems, according to a new study. The study involved an on-road driving test with 32...

Murine cerebral amyloidosis models exhibit impaired vascular formation.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Murine cerebral amyloidosis models exhibit impaired vascular formation. "Abeta peptides are naturally occurring peptides, which are thought to play a key role in the pathophysiology of Alzheimer...

S- but not R-enantiomers of flurbiprofen and ibuprofen are neuroprotective.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- S- but not R-enantiomers of flurbiprofen and ibuprofen are neuroprotective. According to recent research from Canada, "The protective effects of non-steroidal anti-inflammatory drugs (NSAIDs) in...

Spermidine and spermine levels higher in female ALS patients than males.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Study data suggest that regulation of polyamine levels is maintained in end-stage amyotrophic lateral sclerosis, and, interestingly, show that in female patients, spermidine and spermine levels in the...

Hazards of surgery and anesthesia for drug, alcohol abusers presented at meeting.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Substance abusers who think it's okay not to tell their oral and maxillofacial surgeon about their drug use are putting themselves at risk for surgical complications, even if they're having a procedure...

Novel airway approach algorithm developed.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A novel airway management algorithm has been developed for anesthesiologists. "Anticipatory decision-making in airway management requires the integration of both history and physical examination...

Patients with cardiac RyR defects had general anesthesia without complications.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A recent report describes the use of volatile anesthetics and succinylcholine in patients with cardiac ryanodine receptor defects. According to the report from Finland, "Familial polymorphic...

Phosphorylation alters Xenopus Ca-activated Cl currents.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Phosphorylation alters Xenopus Ca-activated Cl currents (I[subscript]Cl(Ca)), a finding that could complicate anesthesia research. I[subscript]Cl(Ca) "are used frequently as reporters in functional...

Cellular mechanisms that control regulation of TASK-1 by PAF are examined.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Activation of protein kinase C epsilon inhibits the two-pore domain K[superscript]+ channel, TASK-1, inducing repolarization abnormalities in cardiac ventricular myocytes. "Activation of the...

Combination may provide a potential treatment of arterial thrombotic disorders.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Cilostazol and dipyridamole synergistically inhibit human platelet aggregation Scientists in the United States report, "It has been previously shown that cilostazol (Pletal(R)), a drug for relief of...

Fluid shear stress induces endothelial KLF2 gene expression.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Fluid shear stress induces KLF2 gene expression in endothelial cells. "Fluid shear stress is crucial for maintenance of a properly functioning endothelium," scientists in the United States...

Glycoproteins have a procoagulant role in collagen-dependent thrombus formation.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A recent report described facilitating roles of murine platelet glycoprotein Ib and (alpha)IIb(beta)3 in phosphatidylserine exposure during vWF-collagen-induced thrombus formation. According to...

New treatments may soon include agents known as the metabolic modulators.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A recent report discusses metabolic approaches to the management of ischemic heart disease. According to a published report from the United States, "The number of patients with coronary artery...

Rac1 GTPase is a strategic target for tumor elimination.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Rac1 GTPase is a strategic target for tumor elimination. "Hypoxia-induced angiogenesis plays an important role in the malignancy of solid tumors. A number of recent studies including our own have...

Responses to BK of peripheral arteries and coronary arteries correlated.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- The relationship between flow-mediated brachial artery vasodilation and coronary vasomotor responses to bradykinin was compared to those to acetylcholine. According to a study from Japan,...

Serial surveillance of patients is vital after arterial switch operation.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Risk factors for neo-aortic root enlargement and aortic regurgitation following arterial switch operation are described in a recent report. According to a study from the United States, "The...

Slowed VO[subscript]2 kinetics occur only with exercise of the affected limbs.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A recent report describes pulmonary Vo[subscript]2 dynamics during treadmill and arm exercise in peripheral arterial disease. "Slowed pulmonary O[subscript]2 uptake (VO[subscript]2) kinetics in...

Vascular and valvular calcium levels linked.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A significant link between vascular and valvular calcium levels has been demonstrated. In a study conducted by cardiologists in the United States, the "epidemiology of and association between...

aPT IgG is a significant marker for deep vein thrombosis/pulmonary embolism.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A high prevalence of anti-prothrombin antibody has been reported in patients with deep vein thrombosis. According to published research from Japan, "...[Our] study was designed to determine the...

Gene-targeting experiments have elucidated AT[subscript]1 receptor functions.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A recent report describes experiments with type I angiotensin (AT[subscript]1) receptor functions through gene targeting According to recent research published in the journal Acta Physiologica...

Chymase and carboxypeptidase A have key roles in generating and degrading Ang II.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Scientists have reported on the cooperation between mast cell carboxypeptidase A and the chymase mouse mast cell protease 4 in the formation and degradation of angiotensin II. "The octapeptide...

Request submitted to FDA for designated new animal drug listing.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Amarillo Biosciences, Inc., (AMAR) announced that it has submitted requests to the U.S. Food & Drug Administration's (FDA) Office of Minor Use and Minor Species Animal Drug Development (MUMS) for...

Animal models are guiding development of new immunotherapies for cancer.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Animal models are guiding the development of new immunotherapies for cancer. According to recent research published in the Journal of Leukocyte Biology, "Immunotherapy using adoptive cell transfer...

Bacillus anthracis identified by multiprobe microarray hybridization.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Scientists have developed a multiprobe microarray hybridization assay to identify Bacillus anthracis. "We have developed a rapid assay based on microarray analysis of amplified genetic markers for...

In vitro-based potency assay for anthrax vaccine developed.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Scientists have developed an in vitro-based potency assay for anthrax vaccines. According to recent research published in the journal Vaccine, "The potency assay currently used to evaluate...

Combination of amphotericin B formulations improves efficacy.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A combination regimen of standard and liposomal amphotericin B formulations has highly efficient anti-Candida activity in mice. "Amphotericin B may be employed as a potentially toxic deoxycholate...

Electrophoretic assay devised for fosfomycin determination.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A novel electrophoretic assay is suitable for use in clinical measurement of fosfomycin levels. In a study from Austria, a "feasible capillary zone electrophoresis (CZE) method with indirect UV and...

Streptococcolytic enzyme zoocin A is a penicillin-binding protein.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Streptococcolytic enzyme zoocin A is a penicillin-binding protein. "Zoocin A is a streptococcolytic enzyme produced by Streptococcus equi subsp. zooepidemicus 4881 that has an unknown site of...

FDA advisers want stronger suicide risk warnings about child antidepressants.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Antidepressants should come with the nation's strongest warning, in a black box on the label, that they can sometimes cause suicidal behavior in children and teenagers, the U.S. government's scientific...

Company updates the European development status of micafungin.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Fujisawa Pharmaceutical Co., Ltd., announced that it now expects the approval of its injectable candin antifungal agent micafungin in Europe to be in the first half of 2006 because additional data have...

Novel antifungal protein from gold kiwi fruit active against Fusarium oxysporum.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A novel antifungal protein from the gold kiwi fruit is active against Fusarium oxysporum. "An antifungal protein designated actinchinin, with an N-terminal sequence different from that of the...

Two-thirds of prescription antihistamine users test negative for allergies.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A new study in the current issue of Journal of Managed Care Pharmacy concludes that 62% of frequent antihistamine users did not test positive for allergies. The authors recommend that objective...

Ecopia selects four new compounds for further profiling.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Ecopia BioSciences, Inc., (EIA) announced the results of its discovery team's research over the last 5 months, which has led to the identification of 12 novel compounds. Four of the compounds have...

Study shows ACP-103 improves clinical profile of haloperidol treatment.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Acadia Pharmaceuticals, Inc., (ACAD), a biopharmaceutical company utilizing innovative science to fuel drug discovery and clinical development of novel treatments for central nervous system disorders,...

Novel podophyllotoxin derivatives have anti-HIV activity.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Novel podophyllotoxin derivatives have anti-HIV activity. According to recent research from the United States, "A series of novel podophyllotoxin derivatives containing structural modifications at...

Recommendations made for two versus three drugs for postexposure HIV prophylaxis.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Recommendations are made for two versus three drugs for postexposure HIV prophylaxis. "Thousands of health care workers are potentially exposed to human immunodeficiency virus (HIV) each year via...

Alpha-1 gene therapy safely tested in first three patients.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- A gene therapy to combat one of the most common hereditary disorders, alpha-1 antitrypsin deficiency, appears safe in the first three patients to participate in a landmark clinical trial, University of...

Multiferon is an alternative for treating difficult chronic hepatitis C cases.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Multiferon is an alternative for treating difficult hepatitis C virus cases. According to recent research published in the journal Hepato - Gastroenterology, "a currently 65-year-old patient with...

Conservative surgery suggested when isolated lesion causes aortic regurgitation.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Diagnosis, management, and treatment of traumatic aortic regurgitation were the focus of a recent report. "Traumatic aortic valve regurgitation is a rare complication of nonpenetrating thoracic...

Study addresses concern about association with ventricular tachyarrhythmias.
October 5, 2004... 2004 OCT 5 - (NewsRx.com & NewsRx.net) -- Ranolazine reduces the pro-arrhythmic effects of increasing late INa in guinea pig ventricular myocytes. According to a study from the United States, "The new anti-anginal drug ranolazine causes a...