Pharma Business Week articles from February 2004

Pharma Business Week archives from February 2004

New antibiotic effective for diabetic foot infections.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- A clinical trial involving 371 patients in eight countries shows that linezolid, a new antibiotic, is at least as effective as two older therapies for treating diabetic foot infections. The drug...

First enzymatic method for C-[superscript]18F bond formation reported.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Scientists report the first enzymatic method for C-[superscript]18F bond formation. "The use of the key enzyme involved in carbon-fluorine bond formation in Streptomyces cattleya catalyzing the...

Subcontract given to develop anthrax vaccines using nanotechnology.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- BioSante Pharmaceuticals, Inc., (BPA) announced that it has been awarded a subcontract valued at $658,207 for the development of anthrax vaccines for delivery via alternative routes of administration....

Development, marketing agreement signed for milnacipran.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Cypress Bioscience, Inc., (CYPB), Forest Laboratories, Inc., (FRX), and Pierre Fabre Medicament announced that the companies have entered into an agreement for the development and marketing for Cypress'...

Myriad Genetics agreement to include pharmacogenetics.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Myriad Genetics, Inc., (MYGN), and Abbott Laboratories, Inc., (ABT) have expanded their strategic alliance to include a broad new pharmacogenetics program. The research collaboration will focus on...

Swiss regulatory application for Symlin withdrawn.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Amylin Pharmaceuticals, Inc., (AMLN) announced receipt of correspondence from the Swiss Agency for Therapeutic Products (Swissmedic) indicating that Symlin could not be approved for marketing in...

Biopharma adds three clinical-stage oncology drug candidates to its pipeline.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Keryx Biopharmaceuticals, Inc., (KERX) has entered into an agreement to acquire ACCESS Oncology, Inc., a privately held, cancer-focused biotechnology company. The acquired drug portfolio includes...

Partnership extended with vaccine research groups.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Targeted Genetics Corporation (TGEN) announced a 3-year extension of its collaboration agreement with the International AIDS Vaccine Initiative (IAVI) and Columbus Children's Research Institute (CCRI)...

Company submits Powerlink PMA to the FDA.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Endologix, Inc., (ELGX) announced that it has filed its completed premarket approval (PMA) submission with the U.S. Food and Drug Administration (FDA) for the PowerLink System, an endoluminal stent...

Atrisone completes pivotal phase III studies.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Atrix Laboratories, Inc., (ATRX) announced that the company's proprietary acne drug, Atrisone (5% topical dapsone gel) has successfully completed two pivotal phase III clinical efficacy studies. ...

Patient enrollment completed in trials for Velac gel.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Connetics Corporation (CNCT), a specialty pharmaceutical company focused on the development and commercialization of dermatology products, announced that it has completed enrollment in its two phase III...

Analysis of CD8+ T-cell response after adenovirus vaccination presented.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Scientists provide a detailed analysis of the CD8+ T-cell response following adenovirus vaccination in a recent issue of the Journal of Virology. According to a study from Canada, "We examined CD8+...

Media exposure drives how satisfied women and girls are about body image.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Media exposure drives how satisfied women and girls are about body image. "Brief exposure to thin-ideal media images has been shown to have a small but consistent negative impact on women and girls'...

Study looks at teens' use of contraceptives in first relationship.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Among teens who have sex, what influences decision-making about using contraceptives during their first sexual relationship? Being in a longer relationship? Having an older partner? Virginity pledges?...

Fluconazole induces torsades de pointes in intensive care unit patient.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Fluconazole and levofloxacin induced torsades de pointes in an intensive care unit patient. According to a study from the United States, " Patients initiated on fluconazole and levofloxacin should...

Inorganic arsenic therapies may have toxic side effects.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Inorganic arsenic therapies may have toxic side effects. According to published research from the United States, "trivalent inorganic arsenic (arsenite, arsenic trioxide, As (III) is currently...

Lamivudine prevents rituximab-induced hepatitis B virus reactivation.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Lamivudine prevents rituximab-induced hepatitis B virus reactivation. According to researchers in Japan, "we used regimens containing rituximab in the treatment of five hepatitis B virus surface...

Steatohepatitis and excessive weight-gain complicate risperidone therapy.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Steatohepatitis and excessive weight-gain complicate risperidone therapy. "We report on a 17-year-old girl who developed steatohepatitis and marked weight gain during risperidone treatment for...

Medicis announces first shipment of RESTYLANE to physicians.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Medicis (MRX) has made its first shipment of RESTYLANE to physicians. Each initial order includes a comprehensive training disk that is designed to assist physicians with procedure techniques. ...

Adolescent rodents experience milder hangover effects than do adult rodents.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Many people begin to experiment with alcohol use during adolescence, yet relatively little is known about alcohol's effects during this critical stage of development. A study in Alcoholism:...

Genetic variation may influence drinking to relieve social anxiety, improve mood.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Alcohol researchers already know that people who expect positive results from drinking - a better mood or social ease - are more likely than other drinkers to develop alcohol problems. Conversely, those...

Cilomilast modifies dendritic cell migration through skin.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Cilomilast modifies the dendritic cell migration through skin. According to a study from Germany, "The phosphodiesterase 4 inhibitor cilomilast demonstrated strong inhibitory effects in a model of...

The bronchovideoscope detects increased vessel growth in new asthma patients.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- The bronchovideoscope detects increased vessel growth in new asthma patients. "Hypervascularity in the bronchial wall is part of airway remodeling, but has remained an ill-defined process in asthma...

Company reports positive phase III studies of Namenda.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Forest Laboratories, Inc., (FRX) announced that results of a U.S. phase III study of Namenda (memantine HCl) as monotherapy in mild-to-moderate Alzheimer disease show that the drug demonstrated a...

New drug improves outcomes when added to existing therapy for AD.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- The drug memantine lessens the decline in cognition and activities of daily living for patients with moderate to severe Alzheimer disease (AD) who are also receiving donepezil (another drug used to...

Understanding normal aging may provide the key to AD prevention.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Our improved understanding of how to maintain normal brain health is providing tantalizing clues about what may prevent or reduce the likelihood of developing Alzheimer disease (AD), according to...

Using vitamin E and C supplements together may reduce AD risk.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Elderly people who take individual vitamin E and C supplements together may reduce their risk of Alzheimer disease (AD), according to a new report. The public health threat of AD will continue to...

Hemopure regulatory status updated following FDA meeting.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Biopure Corporation (BPUR) reported that, on January 6, 2004, the company and the U.S. Food and Drug Administration (FDA) met at Biopure's request to discuss its reply to the FDA complete response...

Medication reduces angina attacks, increases exercise capacity for patients.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Taken with other anti-anginal medications, the drug ranolazine reduces the frequency of angina and increases exercise capacity in patients with severe chronic angina, according to a new study. ...

Estrogen protects cells from certain death after an ischemic stroke.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Estrogen protects cells from certain death after an ischemic stroke. "Estradiol is a known neurotrophic and neuroprotective factor. Our previous work demonstrated that replacement with physiological...

Glycated compounds spawn angiogenic induction in cultured endothelial cells.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Glycated compounds spawn angiogenic induction in cultured endothelial cells. According to a study from Japan, "glycation has been implicated in the endothelial dysfunction that contributes to both...

Tryptophanyl-tRNA synthetase fragments control response to shear stress.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Tryptophanyl-tRNA synthetase fragments control response to shear stress. According to recent research from the United States, "human tryptophanyl-tRNA synthetase (TrpRS) is active in translation and...

Prostaglandin may worsen lung injury induced by lipopolysaccharide.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- 15-Deoxy-Delta[superscript]12,14-prostaglandin J[subscript]2 may exacerbate acute lung injury induced by lipopolysaccharide in mice. According to recent research published in the European Journal of...

Reversible anosmia reported after amikacin therapy.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Reversible anosmia is possible after amikacin therapy. "Olfactory disorders are among the rare adverse effects of antibiotic therapy," scientists in Switzerland explained. "To date, olfactory...

Cisplatin does not directly effect mitochondrial oxygen consumption.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Study finds that exposures to alkylating agents and anthracyclines produce immediate and dose-dependent impairment of mitochondrial oxygen consumption. According to recent research published in the...

ABC multidrug efflux pump identified in Enterococcus faecalis.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- An ABC multidrug efflux pump, EfrAB, has been identified in Enterococcus faecalis. According to recent research published in the journal Antimicrobial Agents and Chemotherapy, "A DNA fragment...

HSCT safe and effective for Taiwanese SAA patients.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Hematopoietic stem-cell transplantation is safe and effective for Taiwanese SAA patients. According to research from Taiwan, HSCT "is an accepted treatment strategy for patients with severe...

Improved insulin sensitivity seen in sleep apnea patients.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Investigators from Friedrich-Alexander University, Erlangen, Germany, have demonstrated that continuous positive airway pressure (CPAP) treatment rapidly improves insulin sensitivity in patients with...

Lecithins and bile salts inhibit apoptosis in mouse cholangiocytes.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Lecithins and cytoprotective bile salts inhibit bile salt-induced apoptosis in immortalized mouse cholangiocytes. "Bile duct epithelium is physiologically exposed to high concentrations of bile...

Ethnicity may affect allergies in children with asthma.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Puerto Rican and African American children with asthma may be at risk for multiple indoor and outdoor allergies, says a new study. The study found that Puerto Rican children with asthma were up to...

Apolipoprotein-E-deficient mice resistant to atherosclerosis.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Mice deficient in apolipoprotein E but not LDL receptors are resistant to accelerated atherosclerosis associated with obesity. "The aims of this study were to determine whether mice induced to...

Benefits of niacin treatment reviewed.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- The oft-overlooked cardiovascular benefits of niacin have been reviewed. "Cardiovascular event reduction in hypercholesterolemic subjects appropriately emphasizes the prominent role of statin...

Redundancy defines complex nature of cytokines and autoimmunity.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Redundancy defines the complex nature of cytokines and autoimmunity. According to recent research published in the journal Current Opinion in Immunology, "Cytokines are critical mediators in...

Women with systemic lupus erythematosus are at risk for losing bone density.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Women with systemic lupus erythematosus are at risk for losing bone density. According to recent research from Bulgaria, "the aim of this study was to analyze the heterogeneity of bone mineral...

Oxford bioincubator wins international recognition.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- The highly successful bioincubator, the Oxford BioBusiness Center, has won the prestigious international award Best Science-Based Incubator 2003. The annual conference Best Practice in Science-Based...

Wang recognized for contributions to molecular biology.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Dr. Xiaodong Wang, professor of biochemistry at the University of Texas (UT) Southwestern Medical Center at Dallas, has been awarded the prestigious National Academy of Sciences Award in Molecular...

Amino acid sequences of subtilisin from alkaliphilic Bacillus reported.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Researchers have published the nucleotide and deduced amino acid sequences of a high-molecular-mass subtilisin from an alkaliphilic Bacillus isolate in a recent issue of Biochimica et Biophysica Acta -...

TetL tetracycline efflux protein from Bacillus subtilis is dimer in membrane.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- The TetL tetracycline efflux protein from Bacillus subtilis is a dimer in the membrane and in detergent solution. According to recent research published in the journal Biochemistry, "The TetL...

EpiCept provides update on two deals made in 2003.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- EpiCept Corp., a privately held specialty pharmaceutical company, reported that two corporate deals completed in 2003 have the potential, if certain conditions are met, to generate in excess of $100...

A new computer model simulates the mechanics of bone turnover at menopause.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- A new computer model simulates the mechanics of bone turnover at menopause. "Antiresorptive drugs are widely used to prevent osteoporotic fractures in men and women. Large clinical trials have shown...

CD105/endoglin is a marker for endometrial cancer angiogenesis.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- CD105/endoglin is a marker for endometrial cancer angiogenesis. "Angiogenesis is a key process in tumor growth and metastasis, and factor-VIII microvascular density has been found to influence...

Bipolar I disorder biobank collection launched.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- PrecisionMed Inc. announced the launch of its new PrecisionMed Sample Bank collection of DNA, RNA, plasma, serum and urine from 200 subjects with bipolar I disorder and 200 matched controls. This...

Karyometry can detect abnormalities in normal urothelium near carcinoma.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Study finds that karyometry can detect an abnormal chromatin pattern and distribution in the normal-looking urothelium adjacent to papillary carcinoma. According to a study from Italy, "This study...

$1.1M contract awarded to study counter-bioterrorism vaccine.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Covalent Group, Inc., (CVGR) announced that it has signed a new contract with DynPort Vaccine Company, LLC, (DVC) for a phase I study in the development of a recombinant vaccine designed to provide...

Gliadel prolongs survival and time to relapse in some glioma patients.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Study finds that Gliadel improves survival and time to relapse, and that possibly expanding the indications for its use should be investigated. According to recent research from Scotland, "The...

Idarubicin unlikely to be used for treating primary CNS tumors.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Study results indicate that it is unlikely that Idarubicin (IDA), daunomycin, or other related anthracyclines will be useful for treating primary CNS tumors," researchers say. "IDA, the 4-demethoxy...

Anthracyclines activate antiapoptotic phosphorylation in breast cancer.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Studies support the ability of anthracyclines to activate antiapoptotic p44/42-MAPK phosphorylation in breast cancer, possibly via the novel mechanism of repression of MKP-1 transcription. ...

Beta[subscript]3 integrin expression can lead to increased tumor cell aggressiveness.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Study suggest that increased expression of the alpha[subscript]vbeta[subscript]3 integrin during breast cancer progression can result in increased tumor cell aggressiveness. "Osteopontin (OPN) is a...

Breast cancer resistance protein is a MTX and MTX-polyglutamate transporter.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Study data show that that breast cancer resistance protein (BCRP) is a methotrexate (MTX) and MTX-polyglutamate transporter and reveal a possible mechanism by which it confers resistance. According...

Increased breast cancer risk may be related to the HLA class III subregion.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Study results show a potential role of the HLA class III subregion in susceptibility to breast cancer. According to a study from Netherlands, "BRCA1 and BRCA2 germline mutations account for ...

NSAIDs may have chemopreventive effect against breast cancer.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Preliminary results from the Women's Health Initiative (WHI) indicate that regular use of aspirin, ibuprofen, or other NSAIDs may have a significant chemopreventive effect against breast cancer. ...

Nematode finding could shed light on BRCA1-involved cancers.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Our common evolutionary heritage with the humble nematode worm is helping unravel one of the key genetic puzzles in breast cancer. For the first time, Cancer Research UK researchers have found a...

P1 homozygosity may be a potential risk factor in breast carcinogenesis.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Research suggests that P1 homozygosity could possibly be a risk factor in breast carcinogenesis. According to a study from Greece, "H-ras is a member of the ras superfamily of genes. This gene...

Pooled analysis of LOH in breast cancer finds many nonreproducible results.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Researchers compile a database of loss of heterozygosity (LOH) studies of breast cancer that lays a framework for further investigation. "Somatic loss of heterozygosity (LOH) has been widely...

Researchers study familial and early onset breast cancer in African Americans.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- In order to identify the spectrum of BRCA2 mutations in African Americans, researchers investigated breast or ovarian cancer patients from 74 independent families at elevated risk of germline mutations....

Risk differs among specific ethnic subgroups of South Asian women in U.K.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Cancer Research UK scientists have discovered that the risk of breast cancer among South Asian women in Britain differs according to their specific ethnic subgroup. Published in the January 6,...

Sequential drugs followed by TRAIL may be a new therapeutic approach for cancer.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Researchers report that sequential administration of chemotherapeutic drugs followed by TRAIL may be an effective new therapy for cancer. "According to published research from the United States,...

Side effects make physicians, patients reluctant to use tamoxifen for DCIS.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Physicians and patients alike are reluctant to use tamoxifen, an adjuvant therapy in the treatment of the very earliest form of breast cancer - ductal carcinoma in situ (DCIS) - because of its side...

Steroid hormone-resistant breast cancer can be sensitive to growth factors.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Researchers establish numerous regulatory links between signal transduction pathways elicited by peptide growth factors and progesterone receptors (PR). "Breast cancers often have increased...

Underarm cosmetics with estrogen may contribute to breast cancer.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Further work is needed to determine whether the use of underarm cosmetics (particularly containing estrogenic formulants) contributes to the rising incidence of breast cancer. "A recent review by...

Many BRCA1 and BRCA2 genes mutations are unique to Spain.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Knowledge about the spectrum of BRCA1 and BRCA2 mutations will improve the detection strategy in countries with large Spanish populations, researchers say. According to published research from...

Kahalalide F preferentially induces cell death via oncosis in tumor cells.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Study show that Kahalalide F (KF) induces cell death via oncosis preferentially in human and prostate cancer cell lines. According to a study from Spain, "Kahalalide F is a novel antitumor drug of...

Pharmaceutical distribution contract renewal announced.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Healthcare services company McKesson Corporation (NYSE:MCK) has signed a 5-year pharmaceutical distribution contract renewal with prescription benefit manager Caremark Rx, Inc. The agreement calls...

Prescription benefits manager cleared for military contract.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Congressional investigators cleared the way for a $245 million U.S. military contract with Missouri-based Express Scripts Inc. Express Scripts is the third-largest manager of prescription drug...

Type 1 diabetes increases cancer risk.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- A population-based cohort study in Sweden revealed that type 1 diabetes increases the risk of several types of cancer. According to recent research from Sweden, "Although patients with type 2...

Canstatin-N fragment stops endothelial cell proliferation and tumor growth.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Canstatin-N fragment stops endothelial cell proliferation and tumor growth. "Type IV collagen is one of the components of vascular basement involved in regulation of angiogenesis. Canstatin, the...

Computerized clinical reminders are helpful for physician prescribing behavior.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Study finds that clinical reminders to physicians helped patients receive treatment with erythropoietin. "The objective of this study is to examine the impact of a clinical reminder generated by an...

Data shows CF101 to be effective in restraining growth of certain cancers.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Can-Fite BioPharma announced new preclinical study results, published in three peer reviewed, high score scientific journals: the Journal of Biological Chemistry, the British Journal of Cancer, and...

Enrollment complete for phase II clinical study in non-Hodgkin lymphoma.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Favrille, Inc., has completed enrollment for its current phase II clinical trial (FavId-04) with the company's lead investigational agent, FavId. This agent is under clinical development for the...

FLAG[+ or -]Ida suitable for induction chemo in high-risk leukemia, MDS patients.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- FLAG[+ or -]Ida is safe and effective as induction chemotherapy in high-risk leukemia and MDS patients. According to recent research from England, "The combination of fludarabine (FDR), high dose...

Fusion proteins steer tumor necrosis factor-alpha to tumor blood vessels.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Fusion proteins steer tumor necrosis factor-alpha to tumor blood vessels. According to researchers writing in the journal Blood, "we sought to enhance the selective toxicity of tumor necrosis factor...

Granulocyte colony-stimulating factor reduces complications in elderly patients.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Further research studies are needed to identify the elderly patients who will benefit most from prophylactic granulocyte colony-stimulating factor (G-CSF). "According to recent research from Italy,...

Standard chemotherapies target specific sectors of the angiogenic cascade.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Standard chemotherapies target specific sectors of the angiogenic cascade. According to a study from Sweden, "tumors are angiogenesis dependent. Some chemotherapeutics have been shown to be able to...

Tumor cells plus adjuvant induced immunity against hepatoma.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Fixed tumor cells in combination with adjuvant induced protective antitumor immunity in a murine hepatoma model. According to recent research published in the journal Cancer Letters, "We previously...