Clinical Oncology Week articles from June 2009

Clinical Oncology Week archives from June 2009

Transplant patients have worse cancer outcomes, analysis shows.
June 1, 2009... After comparing two patient cancer registries--one featuring transplant patients and the other the general population--researchers at the University of Cincinnati (UC) have found that transplant patients experience worse outcomes from cancer...

A surprise 'spark' for pre-cancerous colon polyps.
June 1, 2009... Researchers at Huntsman Cancer Institute (HCI) at the University of Utah studied the events leading to colon cancer and found that an unexpected protein serves as the "spark" that triggers formation of colon polyps, the precursors to cancerous...

Data on cancer gene therapy published by researchers at University Hospital.
June 1, 2009... Data detailed in 'Expression and function of the coxsackie and adenovirus receptor in Barrett's esophagus and associated neoplasia' have been presented. According to recent research published in the journal Cancer Gene Therapy, "Cell surface...

Data on cancer gene therapy reported by researchers at Academic Medical Center.
June 1, 2009... Fresh data on cancer gene therapy are presented in the report 'Allele-specific cancer cell killing in vitro and in vivo targeting a single-nucleotide polymorphism in POLR2A.' "Cancer is one of the diseases for which RNA interference is a...

National Cancer Center Research Institute describes research in cancer gene therapy.(Report)
June 1, 2009... Fresh data on cancer gene therapy are presented in the report 'Intratumoral interferon-alpha gene transfer enhances tumor immunity after allogeneic hematopoietic stem cell transplantation.' According to recent research from Chuo, Japan, "One of...

Key protein may explain the anti-aging and anti-cancer benefits of dietary restriction.
June 8, 2009... A protein that plays a key role in tumor formation, oxygen metabolism and inflammation is involved in a pathway that extends lifespan by dietary restriction. The finding, which appears in the May 22, 2009 edition of the on-line journal PLoS...

In retinal disease, sight may depend on second sites.
June 8, 2009... If two people have the same genetic disease, why would one person go blind in childhood but the other later in life or not at all? For a group of genetic diseases -- so-called ciliary diseases that include Bardet-Biedl syndrome, Meckel-Gruber...

Lifelong cancer risk for patients treated for childhood cancer.(Report)
June 8, 2009... Childhood cancer survivors have a persistent and high risk for a second primary cancer throughout their lives, according to a new study published in the May 26 online issue of the Journal of the National Cancer Institute (see also Journal of...

NYU School of Medicine pathology researchers solve another mystery in B lymphocyte development.
June 8, 2009... A new study published online in Nature Immunology ahead of the June 2009 print issue has found that homologous immunoglobulin (lg) alleles pair up in the nucleus at stages that coincide with V(D)J recombination of the heavy and light chain (Igh...

Zebrafish provide a model for cancerous melanoma in humans.
June 8, 2009... In a new study published in Disease Models & Mechanisms, scientists use the zebrafish to gain insight into the influence of known cancer genes on the development and progression of melanoma, an aggressive form of human skin cancer with limited...

Mayo Clinic finds new pathology tests double sensitivity to detect bile duct and pancreatic cancers.
June 15, 2009... Pancreatic cancer and bile duct cancer are difficult to diagnose and often fatal because they are discovered in the advanced stages of the disease. Researchers have developed new tests that double the ability to detect bile duct and pancreatic...

New study shows people with mental health problems receive inadequate medical care.(Report)
June 15, 2009... New research led by the University of Leicester and published this week in the British Journal of Psychiatry reveals that people with mental health problems are receiving inferior care for their medical needs (see also University of Leicester)....

Penn researchers discover genetic risk factor for testicular cancer.
June 15, 2009... Researchers at the University of Pennsylvania School of Medicine have uncovered variation around two genes that are associated with an increased risk of testicular cancer. Testicular cancer is the most common cancer among young men, and its...

New gene therapy research from Aarhus University discussed.
June 15, 2009... According to recent research published in the journal Human Gene Therapy, "Retroviral vector-mediated gene transfer has been used successfully in clinical gene therapy. Cells of the hematopoietic lineages, however, remain difficult to...

Access Pharmaceuticals Announces Publication of Thiarabine Combination Data.
June 15, 2009... ACCESS PHARMACEUTICALS, INC. (OTC Bulletin Board: ACCP), announced that new Thiarabine preclinical efficacy data will shortly be published demonstrating that thiarabine combined with clofarabine provides much greater antitumor activity than...

2 studies find patients have lower health-related quality of life after cancer diagnosis.
June 22, 2009... Cancer patients who are older than 65 years have poorer physical health and, in some cases, mental health when compared with people of the same age group without cancer, according to a study in the June 9 online issue of the Journal of the...

Variability in pancreatic cancer care found with newly developed quality indicators.(Report)
June 22, 2009... A set of expert consensus-based, quality-of-care indicators identified considerable variability in the quality of pancreatic cancer care among hospitals and may be used to evaluate and identify areas for improvement, according to a new study in...

Cancer screening fear is fueled by lack of information says review covering nearly 6,000 women.
June 22, 2009... Fear plays a major role in whether women decide to go for cancer screening or not, but healthcare providers underestimate how much women need to know and wrongly assume that they will ask for information if they want it (see also...

Scientists at University of Texas, M.D. Anderson Cancer Center discuss research in cancer gene therapy.(Report)
June 22, 2009... New research, 'Artemis is a negative regulator of p53 in response to oxidative stress,' is the subject of a report. According to recent research published in the journal Oncogene, "Artemis is a multifunctional phospho-protein with roles in...

Studies from Mount Sinai School of Medicine, Department of Oncological Sciences in the area of cancer gene therapy published.
June 22, 2009... New investigation results, 'Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma,' are detailed in a study published in Oncogene. "Lung cancer is the most common cause of...

Less invasive CT-scan based colorectal cancer screening method shows good accuracy.
June 29, 2009... This release is available in Chinese (see also JAMA and Archives Journals). Computed tomographic (CT) colonography may offer patients at increased risk of colorectal cancer an alternative to colonoscopy that is less-invasive, is...

Promising biomarker and candidate tumor suppressor gene identified for colorectal cancer.
June 29, 2009... Researchers have identified a new candidate tumor suppressor gene in colorectal cancer and examined its use as a potential biomarker in stool samples, according to a new study published online June 17 in the Journal of the National Cancer...

'Cannabis alters human DNA' -- new study.
June 29, 2009... A new study published by University of Leicester researchers has found "convincing evidence" that cannabis smoke damages DNA in ways that could potentially increase the risk of cancer development in humans (see also University of Leicester)....

Study finds segregation decreases access to surgical care for minorities.(Report)
June 29, 2009... New research published in the June issue of the Journal of the American College of Surgeons reveals that in counties with the highest levels of segregation, an increase in the African-American or Hispanic population was associated with a...

Diet may reduce risk of prostate cancer.
June 29, 2009... A new review published in the Journal of Human Nutrition and Dietetics assessed whether certain modifications in diet have a beneficial effect on the prevention of prostate cancer. Results suggest that a diet low in fat and red meat and high in...