Clinical Oncology Week articles from July 2004

Clinical Oncology Week archives from July 2004

Widely reported cognitive side effect of chemotherapy may be overestimated.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- A new study says the incidence of "chemobrain," a widely reported side effect in women undergoing treatment for breast cancer, may be overestimated. Researchers found significant deficits in...

Report: Taxotere offers significant benefits for head and neck cancer patients.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- The European Organization for Research and Treatment of Cancer (EORTC) announced results from its phase III trial that the addition of Taxotere (docetaxel) Injection Concentrate to a standard therapy...

Study: Oral Xeloda is equivalent IV chemo in adjuvant colon cancer.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Xeloda, an oral tablet, could replace the most widely-used intravenous (IV) chemotherapy for colon cancer, according to new results from a large international phase III study presented at the 40th...

Voice quality after radiotherapy or laser cordectomy for glottic cancer compared.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Voice quality after radiotherapy or laser cordectomy for glottic carcinoma has been compared. "The purpose of this study was to assess the anatomic and functional outcomes and compare the voice...

Autologous transplantation is an effective salvage treatment for recurrent HL.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Autologous transplantation is an effective salvage treatment for recurrent HL. "Our purpose was to study the risk factors associated with disease progression after high-dose chemotherapy followed by...

Surgical interdisciplinarity is needed for abdominal surgery.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Interdisciplinary cooperation between surgical specialties is necessary for optimal treatment outcome, researchers say. According to a study from Germany, "Cooperation between different surgical...

Positive ACAPODENE data presented at ASCO meeting.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- GTx, Inc., (GTXI), a biopharmaceutical company dedicated to the discovery, development, and commercialization of therapeutics primarily related to the treatment of serious men's health conditions,...

Bone metastasis is an infrequent first sign solid tumor spread.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Excluding prostate tumors, bone metastases is not a common indicator of the first sign of metastatic spread in solid tumor patients. In a retrospective study, published in the journal International...

Quality of life in long-term survivors of pediatric brain stem tumors can suffer.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Researchers find that long-term survivors of brain stem tumors during childhood may have neurological impairments. "The quality of life in long-term survivors of pediatric brain stem tumors treated...

Blood test detects genetic changes in progressive disease.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Researchers at the University of Texas Southwestern Medical Center at Dallas have developed a blood test that can detect amplification of a certain gene found in circulating cells associated with breast...

Breast surgery and radiotherapy affect arm, shoulder mobility and strength.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Study finds that patients treated with modified radical mastectomy and radiotherapy as well as patients not irradiated have deficits in some arm and shoulder motions and strength. According to a...

Counseling improves women's functioning.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Counseling helps women cope with their risk of breast cancer. According to a study from the United States, "Helping people cope with health risks is an important area for research and practice....

Multiple mRNA markers detect metastases in sentinel lymph nodes.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Multiple mRNA markers detect metastases in the sentinel lymph nodes of breast cancer patients. "Disseminated breast tumor cells in sentinel lymph nodes (SNs) were evaluated by quantitative real-time...

New prognostic markers for survival of breast cancer identified.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- New prognostic markers for survival of breast cancer have been identified. According to a study from England, "The normal duct-lobular system of the breast is lined by two epithelial cell types,...

New tumor subtypes with poor clinical outcomes characterized.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- A University of North Carolina (UNC) molecular biologist has identified the pattern of genes that characterize a biologically distinct subtype of estrogen receptor negative breast tumor. Because...

Oncogenic marker is a powerful prognostic tool.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- The P70 S6 kinase protein (PS6K) predicts poor locoregional control and may have clinical value in choosing a strategy in breast care patients, according to a study from The Netherlands. "The...

Study investigates resistance to tamoxifen and possible way to reverse it.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- A new study has found a possible mechanism for tamoxifen resistance in breast cancer and provides evidence that another cancer drug - gefitinib (AstraZeneca brand name: Iressa) - may be able to restore...

Study offers new target to stop cancer growth.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Two proteins that normally help cells move from place to place and are made in large quantities in breast cancer cells work together to promote the survival and spread of breast cancer, according to a...

Three novel hormone-responsive cell lines expand research armory.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Researchers in Argentina are pursuing study of three novel cell lines that look promising as tools for examining breast cancer in vitro. "Human breast cancer primary cultures are useful tools for...

Near-infrared imaging detects HER-2 overexpression by tumor cells.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Near-infrared flourescence imaging can be used to detect HER-2 overexpression by tumor cells. Radiologists in Germany conducted a study "to evaluate in vitro and in vivo imaging of...

Cancer research effort nets $350,000 from lemonade stands.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Alex's Lemonade Stand, the charity started by a young cancer patient to benefit cancer research, tallied $350,000 in donations as of June 14, 2004, from lemonade fund-raisers held nationwide over the...

A model for analyzing risks of groundwater contamination is developed.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Researchers develop a method for analyzing cancer risk associated with waste landfill sites. "An integrated simulation-assessment modeling approach for analyzing environmental risks of groundwater...

Arsenic in drinking water in Bangladesh increases risk of some cancer.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Drinking water in Bangladesh has high levels of contaminated with arsenic, which can double the lifetime mortality risk for some cancers. According to recent research from the United States, "We...

Company initiates phase II corporate clinical program for KRX-0401 (Perifosine).
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Keryx Biopharmaceuticals, Inc., (KERX) announced the initiation of a corporate-sponsored clinical program for KRX-0401 (Perifosine), a novel, oral, AKT inhibitor for the treatment of cancer. In...

Company summarizes survival benefits in key patient subsets from BR.21 study.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- OSI Pharmaceuticals, Inc., (OSIP) announced that a summary of data presented at the 40th annual meeting of the American Society of Clinical Oncology (ASCO) summarizing the treatment benefit observed in...

Data: Onco TCS has potential in first-line lymphoma.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Inex Pharmaceuticals Corp. (IEX) and Enzon Pharmaceuticals, Inc., (ENZN) released follow-up results from a phase II clinical trial that indicate Onco TCS (vincristine sulfate liposomes injection) has...

Key Herceptin data presented at ASCO meeting.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Genentech, Inc., (DNA) announced updated results from a phase III study evaluating Herceptin (Trastuzumab) in combination with paclitaxel and carboplatin, as well as a retrospective analysis of the...

Lapatinib shows antitumor activity in herceptin-resistant breast cancer patients.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- GlaxoSmithKline (GSK) announced interim results of a once-daily oral dose of lapatinib (GW572016) from a phase II clinical study presented at the 40th annual meeting of the American Society of Clinical...

Manipulating master molecule disrupts vascular environment for tumors.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Targeting a master molecule that helps cancer cells survive when blood oxygen levels are low may offer a potentially powerful strategy for blocking tumor growth, say researchers at the University of...

NSABP protocol C-06: Oral chemotherapy equally effective and tolerated.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Five-year results of NSABP (National Surgical Adjuvant Breast and Bowel Project) Protocol C-06 that compared oral chemotherapy (UFT/leucovorin) with intravenous chemotherapy (5-FU/leucovorin)...

Polypropylenimine dendrimers enable delivery of ODN to cancer cells.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Polypropylenimine dendrimers provide a delivery route for therapeutic oligonucleotides to cancer cells. Researchers in the U.S. "used polypropylenimine dendrimers for delivering a 31 nt...

Trial results reported in HGS-ETR1 in patients with advanced cancers.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Human Genome Sciences, Inc., (HGSI) announced that the results of ongoing phase I clinical trials demonstrate the safety and tolerability of HGS-ETR1 (agonistic human monoclonal antibody to TRAIL...

Updated phase II lung cancer clinical trial results presented at ASCO.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Genaera Corp. (GENR) announced updated interim safety and efficacy results for its antiangiogenic drug, squalamine, in its phase IIb non-small cell lung cancer (NSCLC) clinical trial. The...

University of Connecticut planning to make cancer center one of nation's elite.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- The director of the University of Connecticut Health Center has unveiled an ambitious $20 million, 5-year plan to make the college's cancer center one of the nation's best. The cancer center's...

Immunological therapies in lymphoproliferative disorders reviewed.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- A scientist reviews the accomplishments and perspectives of immunological interventions in lymphoproliferative disorders in a recent issue of the Journal of Experimental and Clinical Cancer Research....

MabCampath continues to improve survival for patients with CLL.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Data from two related studies confirm the ability of MabCampath (alemtuzumab) to clear leukemic cells from the bone marrow of chronic lymphocytic leukemia (CLL) patients, a result known as eradication...

Results announced in phase III trial of Genasense for advanced melanoma.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Genta, Inc., (GNTA) announced the presentation of updated results from its phase III randomized trial of Genasense (oblimersen sodium) Injection plus dacarbazine in patients with advanced melanoma. ...

Data: Panitumumab has single-agent antitumor activity in colorectal cancer.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Amgen, Inc., (AMGN), and Abgenix (ABGX), an antibody-development company, announced interim data from an ongoing phase II study demonstrating that panitumumab (formerly ABX-EGF), a fully human...

Patients with acromegaly have a high prevalence of hyperplastic colonic polyps.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Colonic polyps occur more frequently in patients with acromegaly than in patients with irritable bowel syndrome (IBS), researchers say. "We evaluated the prevalence and features of colonic polyps in...

CTL precursor-oriented peptide vaccine promising for colorectal cancer.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Results from a phase I trial indicate some benefit from cytotoxic T-lymphocyte (CTL) precursor-oriented peptide vaccines for colorectal carcinoma patients. According to recent research from Japan,...

A type of human papillomavirus may be linked to carcinoma of the conjunctiva.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Researchers find human papillomavirus (HPV) is present on the conjunctiva of a majority of a group with squamous cell carcinoma (SCC) of the conjunctiva. "A total of 21 SCC conjunctiva and 22...

Ultrasound could be used to get drugs to tumors.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Ultrasound scans might be most familiar for getting a peek at a developing fetus, but the technology could also be used to treat cancer. A partnership between the University of California (UC)...

Cancer mortality rates in Europe are variable.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Cancer mortality rates in Europe are variable. "Mortality data, abstracted from the World Health Organization database, are presented in tabular form for 26 cancer sites or groups of sites, plus...

Metastatic gastric cancer does not respond to 9-aminocamptothecin (9-AC).
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- A phase II trial shows that continuously infused 9-aminocamptothecin (9-AC) does not lead to response among patients with advanced gastric cancer. "9-AC is a water-insoluble camptothecin derivative...

BRCA1 germline carriers are at risk for more than ovarian cancer.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Women who carry the BRCA1 germline are at risk for not only ovarian cancer, but also fallopian-tube carcinoma and peritoneal papillary serous carcinoma. "A retrospective study was performed to...

HIV-related germ cell tumor not more aggressive than GCT in general population.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- HIV-related germ cell tumor is not more aggressive than GCT in the general population. "Testicular germ cell tumor (GCT) is not an AIDS-defining illness despite an increased incidence in men with...

Anal Pap smears inaccurate predictor of high-grade anal dysplasia.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Anal Pap smears are inaccurate predictors of high-grade anal dysplasia. "We compared the pathological diagnoses obtained by anal Papanicolaou (Pap) smear with those obtained by anal biopsy or by...

A fast-track referral system for head and neck cancer is ineffective.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Researchers find that a rapid referral system for head and neck cancer patients is in need of improved utilization methods. "The NHS Cancer Plan sets out targets for the diagnosis and treatment of...

Final data from INGN 241 phase I study demonstrates clinical, biologic activity.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Introgen Therapeutics, Inc., (INGN) announced that final data from a phase I trial of INGN 241 in patients with solid tumors were presented at the 7th annual meeting of the American Society of Gene...

Investigators present updates for Targretin, AVINZA, and ONTAK at ASCO meeting.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Ligand Pharmaceuticals, Inc., (LGND) announced that several clinical trials and in vitro studies on Targretin (bexarotene), ONTAK (denileukin diftitox), and AVINZA (morphine sulfate extended-release...

Positive results reported for telomerase cancer vaccine clinical trial.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Geron Corp. (GERN) announced the presentation of new positive results from a phase I/II clinical trial of its telomerase therapeutic vaccine in metastatic prostate cancer. The presentation was...

Scientists discover key protein in activating cell death.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Researchers at La Jolla Institute for Allergy & Immunology (LIAI) have identified a key protein (NDUSF1), which is an integral component of the pathway leading to programmed cell death, a natural...

Incidence of neoplastic disorders is higher in patients with celiac disease.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Celiac disease is associated with malignant complications, researchers say. According to recent research published in the Journal of Clinical Gastroenterology, "Prior studies have suggested that the...

Some cases of laryngeal cancer are radioresistant.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Researchers discuss the potential of markers to predict radioresistant, early-stage laryngeal cancer. "Early stage squamous cell carcinoma of the larynx can be effectively cured by radiotherapy,"...

Abnormal chromosomes forecast leukemia relapse.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Patients with acute myeloid leukemia (AML) who enter remission with abnormal chromosomes in bone marrow cells are twice as vulnerable to recurrence of their disease as are AML patients with normal bone...

Priming with rhG-CSF enhances gemtuzumab-ozogamicin efficacy in AML.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Recombinant human granulocyte colony-stimulating factor (rhG-CSF) can enhance the efficacy of gemtuzumab-ozogamicin treatment in AML patients. In a recent study from Italy, "[e]ight elderly patients...

Mesohepatectomy is an alternate option to extended hepatectomy for liver tumors.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Mesohepatectomy is a difficult surgical procedure but has less risk of resulting in liver failure than does extended hepatectomy. According to published research from Germany, "We describe the...

Lung cancer screening recommendations are revised.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- A U.S. task force has updated the 1996 recommendations for lung cancer screening. According to a study from the United States, "This statement summarizes the current U.S. Preventive Services Task...

Dacarbazine induces phototoxic dermatitis in malignant melanoma patients.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Temozolomide does not cause phototoxic dermatitis in patients with malignant melanoma. "Ten patients with malignant melanoma and phototoxic reactions under dacarbazine or 5-(3,3-dimethyl-1-triazeno)...

Algorithm can discriminate invasive melanomas from Clark nevi.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Researchers develop an algorithm that can distinguish invasive melanoma from Clark nevi but is not able to discriminate in situ melanomas from Clark nevi. "As a first step to develop a screening...

Human melanoma cells are highly sensitive to hederacolchiside A1.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Hederacolchiside A1 (Hcol A1) can bind melanin, possibly adding to the higher toxicity of Hcol A1 in pigmented melanoma cells, researchers say. "We previously reported that Hcol A1, a new oleanene...

Imiquimod induces apoptosis in metastatic melanoma cells.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Imiquimod induces apoptosis in metastatic melanoma cells. "Bypassing molecular mechanisms of apoptosis deficiency may be of great utility for the successful treatment of malignant tumors,"...

MDX-010 receives orphan drug designation.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Medarex, Inc., (MEDX) announced that under the U.S. Orphan Drug Act, the U.S Food and Drug Administration (FDA) has granted orphan drug designation to Medarex's fully human anti-CTLA-4 antibody,...

Patients with mycosis fungoides have a high rate of malignant melanoma.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Researchers find an unexplained link between cutaneous T-cell lymphoma and melanoma. Researchers in England, "retrospectively analyzed the first 461 cases entered into our cutaneous lymphoma...

Wide local excision is preferred for resection of most anorectal melanomas.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Researchers in that abdominoperineal resection(APR) and wide local excision (WLE) are statistically equal in terms of patient survival. According to recent research from England, "Anorectal melanoma...

Carboplatin and weekly paclitaxel safely manage advanced lung cancer.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Carboplatin and weekly paclitaxel safely manage advanced lung cancer. "The combination of carboplatin and paclitaxel given every 3 weeks is a tolerated and reasonably active regimen in advanced...

Radiotherapy during pregnancy requires careful choice of linear accelerator.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- It is preferable to withhold radiotherapy on pregnant women with cancer, but should it be unavoidable, researchers have revealed data on fetal dose estimates and risk assessment. "Cancer in...

ThinPrep's ability to distinguish among ovarian cysts found inaccurate.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Thin Prep (Cytyc Corp.) cytological evaluation does not accurately distinguish benign from non-benign ovarian cysts, a recent report demonstrated. According to a study from the United States, "The...

Data from broad Avastin clinical trial program presented at ASCO meeting.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Genentech, Inc., (DNA) announced results from a phase II study evaluating the combination of Avastin (bevacizumab) and gemcitabine chemotherapy in the treatment of metastatic pancreatic cancer and...

Negative prostate biopsy doesn't always mean cancer-free.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Biopsies detect prostate cancer in about one-fourth of men with abnormal screening tests. However, a negative biopsy does not ensure the absence of disease. Repeat prostate biopsies are positive for...

New nonaspirin pain drug proves effective against recurrent cancer.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Early results from a University of North Carolina (UNC) at Chapel Hill School of Medicine study may determine if drugs called Cox-2 inhibitors, a newer type of nonaspirin pain medicine now widely...

Vaccine benefits some prostate cancer patients in biochemical relapse.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Vaccination with autologous dendritic cells pulsed with recombinant human PSA benefits some prostatectomized prostate cancer patients in biochemical relapse. "This study was conducted in prostate...

Reconstructing the extremities after cancer surgery needs interdisciplinary approach.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Researchers stress the importance of an interdisciplinary approach to reconstructing extremities after cancer surgery or trauma. According to recent research published in the journal Chirurg, "In...

New method described for preserving fertility in young women with cancer.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Physicians at the McGill University Health Centre (MUHC) have described a new way to preserve the fertility of women who must undergo chemotherapy. This method, which can be done quickly, does not...

Researchers describe the surgical management of retrorectal tumors.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- While the goal of treating retrorectal tumors is complete resection with free margins, resection of the rectum is rarely necessary, researchers say. "Retrorectal tumors (RRT) constitute an...

Allogeneic transplantation therapeutic option for myeloproliferative diseases.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Allogeneic transplantation is a therapeutic option for myeloproliferative diseases. "The role of allogeneic transplantation for myeloproliferative diseases other than chronic myeloid leukemia is not...

Anthracycline dose most potent predictor of cardiac complications after HSCT.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Anthracycline dose is the most potent predictor of cardiac complications after hematopoietic stem cell transplant. According to a study from Japan, "The value of pre-transplant factors for...

Blood dendritic cells decreased in acute graft-versus-host disease.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Blood dendritic cells are decreased in acute graft-versus-host disease. According to recent research published in the journal Bone Marrow Transplantation, "The recipients of allogeneic hematopoietic...

Chronic GVHD positive role in high-risk hematologic disease with ASCT.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Chronic GVHD has a positive role in patients with high-risk hematologic diseases who have had allogeneic stem cell transplantation. "Although the use of peripheral blood stem cells instead of bone...

Early absolute lymphocyte count useful prognostic marker for infection after SCT.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- An early absolute lymphocyte count is a useful prognostic marker for risk of opportunistic infection following allogeneic stem cell transplant. According to published research from South Korea, "The...

Early hemorrhagic cystitis treatment in THSC patients resolves symptoms.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Early hemorrhagic cystitis treatment in patients receiving hemopoietic stem cell transplantation resolves the symptoms. According to published research from Russia, "Hemorrhagic cystitis (HC) which...

Early response predicts thalidomide efficacy in advanced multiple myeloma.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- An early response predicts thalidomide efficacy in patients with advanced multiple myeloma. According to recent research from Norway, "Sixty-five patients who were primary or secondary refractory...

Growth impairment after Bu/Cy/HSCT may be result of insufficient GH secretion.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Growth impairment after busulphan/cyclophoshamide-based conditioning for hematopoietic stem cell transplant may be the result of insufficient growth hormone secretion. "It is generally assumed that...

HSCT plus fludarabine induces long-term remission in heavily pretreated patients.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Hematopoietic stem cell transplant plus fludarabine induces long-term remission in heavily pretreated patients "Thirty patients with hematological malignancies received peripheral blood stem cells...